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Autism spectrum disorder: Guide for physicians to help families

Date:
January 13, 2014
Source:
Canadian Medical Association Journal
Summary:
Increased awareness of autism spectrum disorder (ASD) is placing huge demands on health care systems and health care professionals to help children and their families cope with the disorder. A comprehensive evidence-based review aims to help physicians provide appropriate medical support to families of children with ASD, from detection to treatment.

Increased awareness of autism spectrum disorder (ASD) is placing huge demands on health care systems and health care professionals to help children and their families cope with the disorder. A comprehensive evidence-based review published in CMAJ (Canadian Medical Association Journal) aims to help physicians provide appropriate medical support to families of children with ASD, from detection to treatment.

"We have come to understand ASD as a remarkably heterogeneous constellation of conditions that covary with other disabilities and disorders (e.g., intellectual disability, epilepsy, ADHD, anxiety disorders) and various medical problems," writes Dr. Stephen Scherer, senior scientist and director of The Centre for Applied Genomics at The Hospital for Sick Children (SickKids) and director of the McLaughlin Centre at the University of Toronto, with coauthors. "Recent discoveries of underlying genomic factors have shown great complexity and implicate various networks of causal factors."

ASD, which includes a variety of traits that range from mild to severe, is estimated to affect about 1% of the population, although it is under-recognized in the developing world.

The review, by specialists in pediatrics, psychiatry, epidemiology, neurology and genetics from across Canada, outlines the current understanding of ASD and best practices for pediatricians, family doctors and specialist clinics, and identifies resources for clinicians.

Topics include:

  • What causes autism?
  • How is ASD diagnosed?
  • How can ASD be detected early?
  • What other illnesses or conditions are associated with ASD?
  • What treatments and interventions are available and effective?

"Community physicians play an essential role in identifying early signs of ASD and ensuring timely diagnosis," write the authors. "The greatest impact on outcome will come from careful attention to parents' concerns, observing early social and communication skills (e.g., interaction with parents and response to simple social games), immediate referral to available intervention services (e.g., infant development and/or speech-language services, and timely referrals for specialized assessments and interventions."

The authors describe "red flags" for autism as well as best practices for treatments, which include behavioural interventions such as applied behaviour analysis. This technique uses a variety of approaches to teach children skills to reduce problem behaviour.

They also touch upon future directions for understanding the disease.

"New experimental therapeutics hold promise for the treatment of core symptoms and have the potential to alter developmental trajectories. Treatments in animal models carrying single gene mutations for disorders associated with ASD are particularly promising. Future research should focus on how we can better match interventions to child and family characteristics through personalized medicine over the lifetime of the patient," the authors conclude.


Story Source:

The above story is based on materials provided by Canadian Medical Association Journal. Note: Materials may be edited for content and length.


Journal Reference:

  1. Evdokia Anagnostou MD, Lonnie Zwaigenbaum MD, Peter Szatmari MD, Eric Fombonne MD, Bridget A. Fernandez MD, Marc Woodbury-Smith MD PhD, Jessica Brian PhD, Susan Bryson PhD, Isabel M. Smith PhD, Irene Drmic PhD, Janet A. Buchanan PhD, Wendy Roberts MD, Stephen W. Scherer PhD. Autism spectrum disorder: advances in evidence-based practice. CMAJ, January 2014

Cite This Page:

Canadian Medical Association Journal. "Autism spectrum disorder: Guide for physicians to help families." ScienceDaily. ScienceDaily, 13 January 2014. <www.sciencedaily.com/releases/2014/01/140113125142.htm>.
Canadian Medical Association Journal. (2014, January 13). Autism spectrum disorder: Guide for physicians to help families. ScienceDaily. Retrieved July 31, 2014 from www.sciencedaily.com/releases/2014/01/140113125142.htm
Canadian Medical Association Journal. "Autism spectrum disorder: Guide for physicians to help families." ScienceDaily. www.sciencedaily.com/releases/2014/01/140113125142.htm (accessed July 31, 2014).

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