Featured Research

from universities, journals, and other organizations

Long-term survival possible for pediatric heart transplant patients

Date:
January 28, 2014
Source:
Society of Thoracic Surgeons
Summary:
Infants and children who undergo heart transplantation are experiencing good outcomes after surgery and may expect to live beyond 15 years post-surgery with reasonable cardiac function and quality of life.

Infants and children who undergo heart transplantation are experiencing good outcomes after surgery and may expect to live beyond 15 years post-surgery with reasonable cardiac function and quality of life, according to a study released today at the 50th Annual Meeting of The Society of Thoracic Surgeons.

Hannah Copeland, MD and colleagues from Loma Linda University in Loma Linda, CA, reviewed medical charts of 337 pediatric heart transplant patients who underwent transplantation at their institution since 1985.

"The average adult survival rate following heart transplantation currently is 10 years," said Dr. Copeland. "We studied survival rates beyond 15 years for pediatric heart transplant patients to learn more about quality of life and factors that led to improved survival."

More than half (54.3% or 183/337) of the pediatric transplant patients in the study group survived at least 15 years past surgery.

The researchers found that of those 15-year survivors, 82.5% (151) were currently alive and showed good heart function at most recent follow-up. Their average ejection fraction was 62%, meaning that 62% of the blood in the left ventricle was pushed out with each heartbeat. A normal ejection fraction is between 55% and 70%.

"Our study demonstrates that pediatric heart transplant patients who live more than 15 years post-surgery can expect to have reasonable cardiac function and quality of life," said Dr. Copeland.

The researchers also found that the main factors limiting long-term survival among pediatric heart transplant patients were graft vasculopathy and renal (kidney) complications. Graft vasculopathy is an accelerated form of coronary artery disease in which artery walls progressively thicken due to plaque buildup. Repeat heart transplantation can be performed to treat graft vasculopathy, while kidney transplantation can be performed on patients who develop renal complications.

"While major challenges still exist for long-term survival in kids, close surveillance lifelong monitoring, and with advances in immunosuppression medications, the lifespan of the patient can be prolonged," said Dr. Copeland. "Pediatric heart transplant is not a cure, but a chance at life."


Story Source:

The above story is based on materials provided by Society of Thoracic Surgeons. Note: Materials may be edited for content and length.


Cite This Page:

Society of Thoracic Surgeons. "Long-term survival possible for pediatric heart transplant patients." ScienceDaily. ScienceDaily, 28 January 2014. <www.sciencedaily.com/releases/2014/01/140128094147.htm>.
Society of Thoracic Surgeons. (2014, January 28). Long-term survival possible for pediatric heart transplant patients. ScienceDaily. Retrieved April 18, 2014 from www.sciencedaily.com/releases/2014/01/140128094147.htm
Society of Thoracic Surgeons. "Long-term survival possible for pediatric heart transplant patients." ScienceDaily. www.sciencedaily.com/releases/2014/01/140128094147.htm (accessed April 18, 2014).

Share This



More Health & Medicine News

Friday, April 18, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Obama: 8 Million Healthcare Signups

Obama: 8 Million Healthcare Signups

AP (Apr. 17, 2014) President Barack Obama gave a briefing Thursday announcing 8 million people have signed up under the Affordable Care Act. He blasted continued Republican efforts to repeal the law. (April 17) Video provided by AP
Powered by NewsLook.com
Is Apathy A Sign Of A Shrinking Brain?

Is Apathy A Sign Of A Shrinking Brain?

Newsy (Apr. 17, 2014) A recent study links apathetic feelings to a smaller brain. Researchers say the results indicate a need for apathy screening for at-risk seniors. Video provided by Newsy
Powered by NewsLook.com
Could Even Casual Marijuana Use Alter Your Brain?

Could Even Casual Marijuana Use Alter Your Brain?

Newsy (Apr. 16, 2014) A new study conducted by researchers at Northwestern and Harvard suggests even casual marijuana use can alter your brain. Video provided by Newsy
Powered by NewsLook.com
Thousands Of Vials Of SARS Virus Go Missing

Thousands Of Vials Of SARS Virus Go Missing

Newsy (Apr. 16, 2014) A research institute in Paris somehow misplaced more than 2,000 vials of the deadly SARS virus. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins