Featured Research

from universities, journals, and other organizations

Women 35 and older are at decreased risk to have anatomically abnormal child, study suggests

Date:
February 3, 2014
Source:
Society for Maternal-Fetal Medicine
Summary:
In a new study, researchers report that women ages 35 and older are at a decreased risk of having a child with a major congenital malformation, after excluding chromosomal abnormalities.

In a study to be presented on Feb. 6 at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting™, in New Orleans, researchers will report that women ages 35 and older are at a decreased risk of having a child with a major congenital malformation, after excluding chromosomal abnormalities.

Advanced maternal age, traditionally defined as 35 and older, is a well-established risk factor for having a child with a chromosomal abnormality, such as Down syndrome. However, little information is available regarding the association between advanced maternal age and the risk for having a child with a major congenital malformation -- a physical defect present at birth that can involve different parts of the body, including but not limited to the heart, brain, kidney, bones or intestinal track.

In order to address this question, this retrospective study used obstetric and ultrasound information collected from over 76,000 women at the time they presented for their routine second trimester ultrasound at Washington University in St. Louis (Mo.). Researchers compared the incidence of having one or more major congenital malformations diagnosed at the time of ultrasound in women who were younger than 35 versus those women 35 years and older.

Also examined was the incidence of major malformations of women categorized by organ system including heart, brain and kidney. Overall, we found that advanced maternal age was associated with a 40 percent decreased risk of having a child with one or more major congenital malformations, after controlling for other risk factors. Specifically, the incidence of brain, kidney, and abdominal wall defects were decreased in this group of women, while the incidence of heart defects was unchanged.

"As more women are choosing to delay childbearing, they are faced with many increased pregnancy risks," said Katherine R. Goetzinger M.D., M.S.C.I., one of the study's researchers. "Findings from this study may provide some reassurance for these women regarding the likelihood of having an anatomically normal child."

Goetzinger, an assistant professor of maternal-fetal medicine at Washington University in St. Louis School of Medicine, also noted that it is possible that advanced maternal age conveys a "survival of the fittest" effect, in which anatomically normal fetuses are more likely to survive.


Story Source:

The above story is based on materials provided by Society for Maternal-Fetal Medicine. Note: Materials may be edited for content and length.


Cite This Page:

Society for Maternal-Fetal Medicine. "Women 35 and older are at decreased risk to have anatomically abnormal child, study suggests." ScienceDaily. ScienceDaily, 3 February 2014. <www.sciencedaily.com/releases/2014/02/140203084521.htm>.
Society for Maternal-Fetal Medicine. (2014, February 3). Women 35 and older are at decreased risk to have anatomically abnormal child, study suggests. ScienceDaily. Retrieved September 15, 2014 from www.sciencedaily.com/releases/2014/02/140203084521.htm
Society for Maternal-Fetal Medicine. "Women 35 and older are at decreased risk to have anatomically abnormal child, study suggests." ScienceDaily. www.sciencedaily.com/releases/2014/02/140203084521.htm (accessed September 15, 2014).

Share This



More Health & Medicine News

Monday, September 15, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Respiratory Virus Spreads To Northeast, Now In 21 States

Respiratory Virus Spreads To Northeast, Now In 21 States

Newsy (Sep. 14, 2014) The respiratory virus Enterovirus D68, which targets children, has spread from the Midwest to 21 states. Video provided by Newsy
Powered by NewsLook.com
Shocker: Journalists Are Utterly Addicted To Coffee

Shocker: Journalists Are Utterly Addicted To Coffee

Newsy (Sep. 13, 2014) A U.K. survey found that journalists consumed the most amount of coffee, but that's only the tip of the coffee-related statistics iceberg. Video provided by Newsy
Powered by NewsLook.com
Contagious Respiratory Illness Continues to Spread Across U.S.

Contagious Respiratory Illness Continues to Spread Across U.S.

Reuters - US Online Video (Sep. 12, 2014) Hundreds of children in several states have been stricken by a serious respiratory illness that is spreading across the U.S. Linda So reports. Video provided by Reuters
Powered by NewsLook.com
Ebola Batters Sierra Leone Economy Too

Ebola Batters Sierra Leone Economy Too

Reuters - Business Video Online (Sep. 12, 2014) The World Health Organisation warns that local health workers in West Africa can't keep up with Ebola - and among those countries hardest hit by the outbreak, the economic damage is coming into focus, too. As David Pollard reports, Sierra Leone admits that growth in one of the poorest economies in the region is taking a beating. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

    Technology News



    Save/Print:
    Share:

    Free Subscriptions


    Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

    Get Social & Mobile


    Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

    Have Feedback?


    Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
    Mobile: iPhone Android Web
    Follow: Facebook Twitter Google+
    Subscribe: RSS Feeds Email Newsletters
    Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins