Featured Research

from universities, journals, and other organizations

Three doses of HPV vaccine recommended against genital warts

Date:
February 11, 2014
Source:
Karolinska Institutet
Summary:
Two doses of vaccine against human papillomavirus (HPV) provide good protection against genital warts, but three doses is better according to an extensive register study.

Two doses of vaccine against human papillomavirus (HPV) provide good protection against genital warts, but three doses is better according to an extensive register study by researchers at Karolinska Institutet in Sweden. The results are published in the scientific periodical JAMA.

Since 2012, girls in Sweden between the ages of 10 and 18 are offered free vaccination against HPV. The vaccine provides protection against various types of HPV, including some that cause cervical cancer and those that cause genital warts. Current recommendation is three doses of the vaccine however there is an ongoing discussion about reducing to a two-dose regime. Currently there is not enough evidence whether two doses are as effective as three in terms of duration of protection.

The researchers behind the current study have taken advantage of the Swedish health care registers to study all girls and young women (between 10 and 24 years of age) in Sweden between 2006 and 2010, in more than a million individuals. The girls were divided into groups, depending on whether they were unvaccinated or had received 1, 2 or 3 doses of the Gardasil vaccine. Almost 8 out 10 of those who were vaccinated during the period received all three doses. The researchers studied the occurrence of genital warts because it is the earliest measurable prevented disease outcome for the HPV vaccine. The vaccine is primarily administered to prevent the occurrence of cervical cancer, which takes significantly longer time to develop and therefore cannot yet be studied. 

In the studied population, more than 20,000 cases of genital warts were noted during the follow-up period, on average 3.8 years. There was an association between the occurrence of genital warts and the number of vaccination doses received.

"When it comes to the vaccine's ability to protect against genital warts in girls between 10 and 16 years of age we can see that two doses provide good protection, up to 71 per cent, but that three doses is better, up to 82 per cent, " says Lisen Arnheim Dahlström at the Department of Medical Epidemiology and Biostatistics at Karolinska Institutet. “Our results suggest that we should continue with the recommended three doses, but open up for a future two-dose schedule after more studies have been conducted regarding the protection against genital warts and initial stages of cervical cancer.”

Between 2007 and 2011, Swedish girls between 13 and 17 years of age were offered subsidized HPV vaccinations. From 2012 HPV vaccination is for free for girls between 10 and 18 years of age.


Story Source:

The above story is based on materials provided by Karolinska Institutet. Note: Materials may be edited for content and length.


Journal Reference:

  1. Eva Herweijer, Amy Leval, Alexander Ploner, Sandra Eloranta, Julia Fridman Simard, Joakim Dillner, Eva Netterlid, Pär Sparén, Lisen Arnheim-Dahlström. Association of Varying Number of Doses of Quadrivalent Human Papillomavirus Vaccine With Incidence of Condyloma. JAMA, 2014; 311 (6): 597 DOI: 10.1001/jama.2014.95

Cite This Page:

Karolinska Institutet. "Three doses of HPV vaccine recommended against genital warts." ScienceDaily. ScienceDaily, 11 February 2014. <www.sciencedaily.com/releases/2014/02/140211162531.htm>.
Karolinska Institutet. (2014, February 11). Three doses of HPV vaccine recommended against genital warts. ScienceDaily. Retrieved August 20, 2014 from www.sciencedaily.com/releases/2014/02/140211162531.htm
Karolinska Institutet. "Three doses of HPV vaccine recommended against genital warts." ScienceDaily. www.sciencedaily.com/releases/2014/02/140211162531.htm (accessed August 20, 2014).

Share This




More Health & Medicine News

Wednesday, August 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Ebola-Hit Sierra Leone's Freetown a City on Edge

Ebola-Hit Sierra Leone's Freetown a City on Edge

AFP (Aug. 19, 2014) — Residents of Sierra Leone's capital voice their fears as the Ebola virus sweeps through west Africa. Duration: 00:56 Video provided by AFP
Powered by NewsLook.com
101-Year-Old Working Man Has All The Advice You Need

101-Year-Old Working Man Has All The Advice You Need

Newsy (Aug. 19, 2014) — Herman Goldman has worked at the same lighting store for almost 75 years. Find out his secrets to a happy, productive life. Video provided by Newsy
Powered by NewsLook.com
Researcher Testing on-Field Concussion Scanners

Researcher Testing on-Field Concussion Scanners

AP (Aug. 19, 2014) — Four Texas high school football programs are trying out an experimental system designed to diagnose concussions on the field. The technology is in response to growing concern over head trauma in America's most watched sport. (Aug. 19) Video provided by AP
Powered by NewsLook.com
American Ebola Patient Apparently Improving, Outbreak Is Not

American Ebola Patient Apparently Improving, Outbreak Is Not

Newsy (Aug. 19, 2014) — Nancy Writebol, an American missionary who contracted Ebola, is apparently getting better, according to her husband. The outbreak, however, is not. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins