Featured Research

from universities, journals, and other organizations

Parkinson's disease: Quickly identifying patients at risk of dementia

Date:
March 10, 2014
Source:
Universite de Montreal
Summary:
It may now be possible to identify the first-stage Parkinson’s patients who will go on to develop dementia, according to a study. Although Parkinson's disease is generally associated with motor problems such as trembling or rigidity, people with this disease actually have a ¬six times greater risk of developing dementia compared to the rest of the population.

It may now be possible to identify the first-stage Parkinson's patients who will go on to develop dementia, according to a study conducted at the Institut universitaire de gériatrie de Montréal by Dr. Oury Monchi, PhD, and his postdoctoral student, Dr. Alexandru Hanganu, MD, PhD, both of whom are affiliated with Université de Montréal. These findings were published in the journal Brain.

Although Parkinson's disease is generally associated with motor problems such as trembling or rigidity, people with this disease actually have a ¬six times greater risk of developing dementia compared to the rest of the population. In this first longitudinal study in this field, 32 patients in the first stages of Parkinson's disease were followed for 20 months. Some of the patients had mild cognitive impairments while others did not. A control group of 18 healthy people were also followed.

"Using magnetic resonance imaging, we found thinning in certain cortical areas as well as subcortical atrophy in the grey matter of subjects with mild cognitive impairments. Thanks to our longitudinal approach, we were able to observe that this thinning speeds up in conjunction with the increase in cognitive problems," explained Dr. Monchi. This specific brain deterioration combined with the early presence of mild cognitive impairments could serve as markers for the development of dementia.

Dr. Monchi stressed the importance of these findings: "This study opens the door to further research, for example, on medication or on non-pharmacological approaches such as transcranial magnetic stimulation. It's important for these patients to be identified very quickly before they develop dementia so that a therapeutic approach can be adapted to their specific needs."


Story Source:

The above story is based on materials provided by Universite de Montreal. Note: Materials may be edited for content and length.


Journal Reference:

  1. A. Hanganu, C. Bedetti, C. Degroot, B. Mejia-Constain, A.-L. Lafontaine, V. Soland, S. Chouinard, M.-A. Bruneau, S. Mellah, S. Belleville, O. Monchi. Mild cognitive impairment is linked with faster rate of cortical thinning in patients with Parkinson's disease longitudinally. Brain, 2014; DOI: 10.1093/brain/awu036

Cite This Page:

Universite de Montreal. "Parkinson's disease: Quickly identifying patients at risk of dementia." ScienceDaily. ScienceDaily, 10 March 2014. <www.sciencedaily.com/releases/2014/03/140310143914.htm>.
Universite de Montreal. (2014, March 10). Parkinson's disease: Quickly identifying patients at risk of dementia. ScienceDaily. Retrieved August 30, 2014 from www.sciencedaily.com/releases/2014/03/140310143914.htm
Universite de Montreal. "Parkinson's disease: Quickly identifying patients at risk of dementia." ScienceDaily. www.sciencedaily.com/releases/2014/03/140310143914.htm (accessed August 30, 2014).

Share This




More Mind & Brain News

Saturday, August 30, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Young Entrepreneurs Get $100,000, If They Quit School

Young Entrepreneurs Get $100,000, If They Quit School

AFP (Aug. 29, 2014) — Twenty college-age students are getting 100,000 dollars from a Silicon Valley leader and a chance to live in San Francisco in order to work on the start-up project of their dreams, but they have to quit school first. Duration: 02:20 Video provided by AFP
Powered by NewsLook.com
Baby Babbling Might Lead To Faster Language Development

Baby Babbling Might Lead To Faster Language Development

Newsy (Aug. 29, 2014) — A new study suggests babies develop language skills more quickly if their parents imitate the babies' sounds and expressions and talk to them often. Video provided by Newsy
Powered by NewsLook.com
Electrical Stimulation Boosts Brain Function, Study Says

Electrical Stimulation Boosts Brain Function, Study Says

Newsy (Aug. 29, 2014) — Researchers found an improvement in memory and learning function in subjects who received electric pulses to their brains. Video provided by Newsy
Powered by NewsLook.com
Treadmill 'trips' May Reduce Falls for Elderly

Treadmill 'trips' May Reduce Falls for Elderly

AP (Aug. 28, 2014) — Scientists are tripping the elderly on purpose in a Chicago lab in an effort to better prevent seniors from falling and injuring themselves in real life. (Aug.28) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins