Featured Research

from universities, journals, and other organizations

Prenatal growth could play key role in South Asians' predisposition to non-communicable diseases

Date:
March 13, 2014
Source:
University of Loughborough
Summary:
A new study in mothers and children of Pakistani origin suggests non-communicable diseases such as cardiovascular disease and Type 2 Diabetes could be programmed prior to birth. Abdominal circumference is thought to represent critical organs such as the kidneys and liver which have key roles in the programming of disease. These latest findings may show that, in Pakistani fetuses, programming of non-communicable diseases begins prenatally.

A new study in mothers and children of Pakistani origin suggests non-communicable diseases such as cardiovascular disease and Type 2 Diabetes could be programmed prior to birth.

Related Articles


South Asians show some of the highest rates of cardiovascular disease in the world which, according to a Loughborough University study, may be traced back to a marked reduction in the prenatal growth of the abdominal circumference, specifically during the third trimester.

Abdominal circumference is thought to represent critical organs such as the kidneys and liver which have key roles in the programming of disease. These latest findings may show that, in Pakistani fetuses, programming of non-communicable diseases begins prenatally.

The study, published in the Annals of Human Biology this month, analyzed more than 5,000 fetuses from the Born in Bradford study -- one of the biggest and most important medical research studies undertaken in the UK. Researchers compared body measurements to identify differences between White British and Pakistani fetuses to help explain why South Asians appear to be more prone to cardiovascular disease.

Researchers found that although there was no difference in prenatal growth between the groups in terms of weight and head size, Pakistani fetuses displayed a marked reduction in growth of the abdominal circumference.

Lead researcher Tom Norris, part of Loughborough University's Centre for Global Health and Human Development, explained:

"It is widely believed that exposures in early life are critical to the development of many of the non-communicable diseases observed in adulthood, but much of the research so far has focused on the infant period and birth weight.

"We wanted to look at even earlier development to start to understand what happens prior to birth, and whether non-communicable diseases might be pre-programd before we are even born.

"The marked difference we discovered in prenatal abdominal circumference growth -- and the established links to the organs important in the programming of disease, may explain why South Asians are more at risk of cardiovascular disease."


Story Source:

The above story is based on materials provided by University of Loughborough. Note: Materials may be edited for content and length.


Journal Reference:

  1. Tom Norris, Derek Tuffnell, John Wright, Noël Cameron. Modelling foetal growth in a bi-ethnic sample: results from the Born in Bradford (BiB) birth cohort. Annals of Human Biology, 2014; 1 DOI: 10.3109/03014460.2014.882412

Cite This Page:

University of Loughborough. "Prenatal growth could play key role in South Asians' predisposition to non-communicable diseases." ScienceDaily. ScienceDaily, 13 March 2014. <www.sciencedaily.com/releases/2014/03/140313122726.htm>.
University of Loughborough. (2014, March 13). Prenatal growth could play key role in South Asians' predisposition to non-communicable diseases. ScienceDaily. Retrieved December 20, 2014 from www.sciencedaily.com/releases/2014/03/140313122726.htm
University of Loughborough. "Prenatal growth could play key role in South Asians' predisposition to non-communicable diseases." ScienceDaily. www.sciencedaily.com/releases/2014/03/140313122726.htm (accessed December 20, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Saturday, December 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

The Best Tips to Curb Holiday Carbs

The Best Tips to Curb Holiday Carbs

Buzz60 (Dec. 19, 2014) — It's hard to resist those delicious but fattening carbs we all crave during the winter months, but there are some ways to stay satisfied without consuming the extra calories. Vanessa Freeman (@VanessaFreeTV) has the details. Video provided by Buzz60
Powered by NewsLook.com
Sierra Leone Bikers Spread the Message to Fight Ebola

Sierra Leone Bikers Spread the Message to Fight Ebola

AFP (Dec. 19, 2014) — More than 100 motorcyclists hit the road to spread awareness messages about Ebola. Nearly 7,000 people have now died from the virus, almost all of them in west Africa, according to the World Health Organization. Video provided by AFP
Powered by NewsLook.com
Researchers Test Colombian Village With High Alzheimer's Rates

Researchers Test Colombian Village With High Alzheimer's Rates

AFP (Dec. 19, 2014) — In Yarumal, a village in N. Colombia, Alzheimer's has ravaged a disproportionately large number of families. A genetic "curse" that may pave the way for research on how to treat the disease that claims a new victim every four seconds. Duration: 02:42 Video provided by AFP
Powered by NewsLook.com
The Best Protein-Filled Foods to Energize You for the New Year

The Best Protein-Filled Foods to Energize You for the New Year

Buzz60 (Dec. 19, 2014) — The new year is coming and nothing will energize you more for 2015 than protein-filled foods. Fitness and nutrition expert John Basedow (@JohnBasedow) gives his favorite high protein foods that will help you build muscle, lose fat and have endless energy. Video provided by Buzz60
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins