Featured Research

from universities, journals, and other organizations

Vibration may help heal chronic wounds

Date:
March 31, 2014
Source:
University of Illinois at Chicago
Summary:
Wounds may heal more quickly if exposed to low-intensity vibration, report researchers. The finding, in mice, may hold promise for the 18 million Americans who have type 2 diabetes, and especially the quarter of them who will eventually suffer from foot ulcers. Their wounds tend to heal slowly and can become chronic or worsen rapidly.

Eileen Weinheimer-Haus, first author, and Timothy Koh, principal investigator.
Credit: Roberta Dupuis-Devlin/UIC Photo Services

Wounds may heal more quickly if exposed to low-intensity vibration, report researchers at the University of Illinois at Chicago.

Related Articles


The finding, in mice, may hold promise for the 18 million Americans who have type 2 diabetes, and especially the quarter of them who will eventually suffer from foot ulcers. Their wounds tend to heal slowly and can become chronic or worsen rapidly.

Timothy Koh, UIC professor of kinesiology and nutrition in the UIC College of Applied Health Sciences, was intrigued by studies at Stony Brook University in New York that used very low-intensity signals to accelerate bone regeneration.

"This technique is already in clinical trials to see if vibration can improve bone health and prevent osteoporosis," Koh said.

Koh and his coworkers at UIC collaborated with Stefan Judex of Stony Brook to investigate whether the same technique might improve wound healing in diabetes. The new study, using an experimental mouse model of diabetes, is published online in the journal PLOS One.

The low-amplitude vibrations are barely perceptible to touch.

"It's more like a buzz than an earthquake," said Eileen Weinheimer-Haus, UIC postdoctoral fellow in kinesiology and nutrition, the first author of the study.

The researchers found that wounds exposed to vibration five times a week for 30 minutes healed more quickly than wounds in mice of a control group.

Wounds exposed to vibration formed more granulation tissue, a type of tissue important early in the wound-healing process. Vibration helped tissue to form new blood vessels -- a process called angiogenesis -- and also led to increased expression of pro-healing growth factors and signaling molecules called chemokines, Weinheimer-Haus said.

"We know that chronic wounds in people with diabetes fail to form granulation tissue and have poor angiogenesis, and we believe these factors contribute to their wounds' failure to heal," said Koh. He and his colleagues want to determine whether the changes they see in cell populations and gene expression at wound sites underlie the observed improvement in healing.

"The exciting thing about this intervention is how easily it could be translated to people," Koh said. "It's a procedure that's non-invasive, doesn't require any drugs, and is already being tested in human trials to see if it's protective of bone loss." A clinical study, in collaboration with Dr. William Ennis, director of the Wound Healing Clinic at UIC, is planned, Koh said.


Story Source:

The above story is based on materials provided by University of Illinois at Chicago. The original article was written by Jeanne Galatzer-Levy. Note: Materials may be edited for content and length.


Journal Reference:

  1. Eileen M. Weinheimer-Haus, Stefan Judex, William J. Ennis, Timothy J. Koh. Low-Intensity Vibration Improves Angiogenesis and Wound Healing in Diabetic Mice. PLoS ONE, 2014; 9 (3): e91355 DOI: 10.1371/journal.pone.0091355

Cite This Page:

University of Illinois at Chicago. "Vibration may help heal chronic wounds." ScienceDaily. ScienceDaily, 31 March 2014. <www.sciencedaily.com/releases/2014/03/140331153647.htm>.
University of Illinois at Chicago. (2014, March 31). Vibration may help heal chronic wounds. ScienceDaily. Retrieved April 18, 2015 from www.sciencedaily.com/releases/2014/03/140331153647.htm
University of Illinois at Chicago. "Vibration may help heal chronic wounds." ScienceDaily. www.sciencedaily.com/releases/2014/03/140331153647.htm (accessed April 18, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Saturday, April 18, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Our Love Of Puppy Dog Eyes Explained By Science

Our Love Of Puppy Dog Eyes Explained By Science

Newsy (Apr. 17, 2015) Researchers found a spike in oxytocin occurs in both humans and dogs when they gaze into each other&apos;s eyes. Video provided by Newsy
Powered by NewsLook.com
Scientists Find Link Between Gestational Diabetes And Autism

Scientists Find Link Between Gestational Diabetes And Autism

Newsy (Apr. 17, 2015) Researchers who analyzed data from over 300,000 kids and their mothers say they&apos;ve found a link between gestational diabetes and autism. Video provided by Newsy
Powered by NewsLook.com
Video Messages Help Reassure Dementia Patients

Video Messages Help Reassure Dementia Patients

AP (Apr. 17, 2015) Family members are prerecording messages as part of a unique pilot program at the Hebrew Home in New York. The videos are trying to help victims of Alzheimer&apos;s disease and other forms of dementia break through the morning fog of forgetfulness. (April 17) Video provided by AP
Powered by NewsLook.com
Boy or Girl? Intersex Awareness Is on the Rise

Boy or Girl? Intersex Awareness Is on the Rise

AP (Apr. 17, 2015) At least 1 in 5,000 U.S. babies are born each year with intersex conditions _ ambiguous genitals because of genetic glitches or hormone problems. Secrecy and surgery are common. But some doctors and activists are trying to change things. (April 17) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins