Featured Research

from universities, journals, and other organizations

Walking may help protect kidney patients against heart disease, infections

Date:
April 3, 2014
Source:
American Society of Nephrology (ASN)
Summary:
In kidney disease patients, 30 minutes of walking improved the responsiveness of certain immune cells to a bacterial challenge and induced a systemic anti-inflammatory environment in the body. Six months of regular walking reduced immune cell activation and markers of systemic inflammation.

Heart disease and infection are major complications and the leading causes of death in patients with chronic kidney disease. It is now well established that immune system dysfunction is involved in both of these pathological processes. Specifically, impaired immune function predisposes to infection, while persistent immune activation leads to a state of chronic inflammation that can damage the insides of blood vessels and increase heart disease risk. Physical exercise may confer benefits by exerting anti-inflammatory effects and enhancing immunity, but such effects have been largely unexplored in kidney disease.

João Viana, PhD, Nicolette Bishop, PhD (Loughborough University, in the UK), and Alice Smith, PhD (University of Leicester) and their colleagues designed a study to explore the impact of exercise on a range of immune and inflammatory parameters in patients with chronic kidney disease.

In an acute exercise study conducted in 15 patients, 30 minutes of walking improved the responsiveness of immune cells called neutrophils to a bacterial challenge in the post-exercise period. It also induced a systemic anti-inflammatory environment in the body.

In a regular exercise study, six months of regular walking (30 minutes/day, five times/week) reduced immune cell activation and markers of systemic inflammation in 20 patients compared with another 20 patients who did not increase their usual activity levels over the same period of time.

“Thus, exercise exerts anti-inflammatory effects in patients with kidney disease and may in this way reduce their high risk for heart disease,” said Dr. Viana. “Our study also found no evidence that this level of exercise might be harmful to the immune system in people with kidney disease.”


Story Source:

The above story is based on materials provided by American Society of Nephrology (ASN). Note: Materials may be edited for content and length.


Journal Reference:

  1. J. L. Viana, G. C. Kosmadakis, E. L. Watson, A. Bevington, J. Feehally, N. C. Bishop, A. C. Smith. Evidence for Anti-Inflammatory Effects of Exercise in CKD. Journal of the American Society of Nephrology, 2014; DOI: 10.1681/ASN.2013070702

Cite This Page:

American Society of Nephrology (ASN). "Walking may help protect kidney patients against heart disease, infections." ScienceDaily. ScienceDaily, 3 April 2014. <www.sciencedaily.com/releases/2014/04/140403212356.htm>.
American Society of Nephrology (ASN). (2014, April 3). Walking may help protect kidney patients against heart disease, infections. ScienceDaily. Retrieved September 21, 2014 from www.sciencedaily.com/releases/2014/04/140403212356.htm
American Society of Nephrology (ASN). "Walking may help protect kidney patients against heart disease, infections." ScienceDaily. www.sciencedaily.com/releases/2014/04/140403212356.htm (accessed September 21, 2014).

Share This



More Health & Medicine News

Sunday, September 21, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Sierra Leone's Nationwide Ebola Curfew Underway

Sierra Leone's Nationwide Ebola Curfew Underway

Newsy (Sep. 20, 2014) — Sierra Leone is locked down as aid workers and volunteers look for new cases of Ebola. Video provided by Newsy
Powered by NewsLook.com
Changes Found In Brain After One Dose Of Antidepressants

Changes Found In Brain After One Dose Of Antidepressants

Newsy (Sep. 19, 2014) — A study suggest antidepressants can kick in much sooner than previously thought. Video provided by Newsy
Powered by NewsLook.com
Could Grief Affect The Immune Systems Of Senior Citizens?

Could Grief Affect The Immune Systems Of Senior Citizens?

Newsy (Sep. 19, 2014) — The study found elderly people are much more likely to become susceptible to infection than younger adults going though a similar situation. Video provided by Newsy
Powered by NewsLook.com
Jury Delivers Verdict in Salmonella Trial

Jury Delivers Verdict in Salmonella Trial

AP (Sep. 19, 2014) — A federal jury has convicted three people in connection with an outbreak of salmonella poisoning five years ago that sickened hundreds of people and was linked to a number of deaths. (Sept. 19) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins