Featured Research

from universities, journals, and other organizations

Reasons for pain after 'successful' spinal surgery

Date:
April 9, 2014
Source:
American Association of Neurological Surgeons (AANS)
Summary:
A new study sheds light on the basis of neuropathic pain that persists after apparently successful surgery. The topic is a question that has long puzzled physicians. In a study that melds the interrelated domains of spinal surgery and pain medicine, researchers have discovered that in the transition from acute inflammatory pain to chronic neuropathic pain, neurons undergo molecular changes.

Understanding why pain persists despite structurally successful spinal surgery is a question that has long puzzled physicians. In a study that melds the interrelated domains of spinal surgery and pain medicine, researchers have discovered that in the transition from acute inflammatory pain to chronic neuropathic pain, neurons undergo molecular changes.

Related Articles


Team leader Mohammed Farid Shamji, MD, PhD, FAANS, presented the study's findings today during the 82nd Annual Scientific Meeting of the American Association of Neurological Surgeons (AANS). Titled "Peripheral Hypersensitivity to Subthreshold Stimuli Persists after Resolution of Acute Experimental Disc-Herniation Neuropathy and Is Mediated by Heightened TRPV1 Receptor Expression and Activity," the study promises to shed light on the basis of neuropathic pain that persists after apparently successful surgery.

Dr. Shamji noted, "It is extremely novel to learn that an autoimmune neuroinflammatory radiculopathy that we clinically manage in most patients as being self-limited has the potential to cause permanent structural changes to neurons and functional sensitivity in the pain experience."

Understanding the molecular changes that occur, said Dr. Shamji, could help researchers develop appropriate treatments. "If we can minimize the disability caused by this pain syndrome, we may be able to prevent it from occurring upon onset of the acute inflammatory pain, potentially even reversing it once established."


Story Source:

The above story is based on materials provided by American Association of Neurological Surgeons (AANS). Note: Materials may be edited for content and length.


Cite This Page:

American Association of Neurological Surgeons (AANS). "Reasons for pain after 'successful' spinal surgery." ScienceDaily. ScienceDaily, 9 April 2014. <www.sciencedaily.com/releases/2014/04/140409204239.htm>.
American Association of Neurological Surgeons (AANS). (2014, April 9). Reasons for pain after 'successful' spinal surgery. ScienceDaily. Retrieved March 2, 2015 from www.sciencedaily.com/releases/2014/04/140409204239.htm
American Association of Neurological Surgeons (AANS). "Reasons for pain after 'successful' spinal surgery." ScienceDaily. www.sciencedaily.com/releases/2014/04/140409204239.htm (accessed March 2, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Monday, March 2, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Treadmill Test Can Predict Chance Of Death Within A Decade

Treadmill Test Can Predict Chance Of Death Within A Decade

Newsy (Mar. 2, 2015) Johns Hopkins researchers analyzed 58,000 heart stress tests to come up with a formula that predicts a person&apos;s chances of dying in the next decade. Video provided by Newsy
Powered by NewsLook.com
Going Gluten-Free Could Get You A Tax Break

Going Gluten-Free Could Get You A Tax Break

Newsy (Mar. 2, 2015) If a doctor advises you to remove gluten from your diet, you could get a tax deduction on the amount you spend on gluten-free foods. Video provided by Newsy
Powered by NewsLook.com
GlaxoSmithKline and Novartis Try Swapping Success

GlaxoSmithKline and Novartis Try Swapping Success

Reuters - Business Video Online (Mar. 2, 2015) GlaxoSmithKline and Novartis have completed a series of asset swaps worth more than $20 billion. As Grace Pascoe reports they say the deal will reshape both drugmakers. Video provided by Reuters
Powered by NewsLook.com
How Can West Africa Rebuild After Ebola?

How Can West Africa Rebuild After Ebola?

Reuters - Business Video Online (Mar. 2, 2015) How best to rebuild the three West African countries struggling with Ebola will be discussed in Brussels this week. As Hayley Platt reports Sierra Leone has the toughest job ahead - its once thriving economy has been ravaged by the disease. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins