Featured Research

from universities, journals, and other organizations

Major lung resection safer than ever, especially at the busiest hospitals

Date:
April 29, 2014
Source:
American Association for Thoracic Surgery (AATS)
Summary:
Major lung surgery has become progressively safer over the last few decades, although higher death rates at low-volume hospitals and an unexpected increase in mortality at 90 days compared to 30 days were observed. The study further suggests that choosing a center that performs major lung surgery regularly can have a strong impact on survival.

A major new study using data from the National Cancer Data Base details the impact of annual hospital volume on 30- and 90-day mortality rates. Investigators found that major lung surgery has become progressively safer over the last few decades, although higher death rates at low-volume hospitals and an unexpected increase in mortality at 90 days compared to 30 days were observed. The study further suggests that choosing a center that performs major lung surgery regularly can have a strong impact on survival.

Related Articles


Lung cancer is the leading cause of death from cancer in both men and women in the U.S. The best chance to cure lung cancer after it develops involves a combination of early detection at an “operable” stage, followed by surgery to remove the portion of the lung where the cancer developed. The number of operations for lung cancer is likely to increase with lung cancer screening.

The study used the National Cancer Data Base (NCDB) cancer treatment and outcomes database, which is a joint project co-sponsored by the American Cancer Society and the American College of Surgeons. The NCDB captures more than 80% of all new lung cancer cases treated in the U.S. each year, and evaluated data for 121,099 patients who underwent major pulmonary resection for lung cancer at more than 1,200 Commission on Cancer-accredited hospitals across the U.S. between 2007 and 2011. Survival at 30 days and 90 days after surgery and numerous risk factors for dying after the surgery were evaluated.

Analysis revealed that at all 1,200+ hospitals combined, 2.8% of patients who underwent major lung surgery (93% of which were lobectomies or bi-lobectomies) died within 30 days after their surgery during this five-year time period. This rate was lower than reported from the busiest hospitals with the highest volume of surgeries just a decade ago. Further analysis showed that annual hospital volume of major lung operations for cancer had a significant impact on both 30-day and 90-day mortality rates. The chance of death was twice as high at hospitals where less than 10 major lung cancer resections per year were performed (3.7%), compared to mortality at the busiest hospitals performing more than 90 such operations per year (1.7%). More than 10,000 of these operations took place at these lowest volume hospitals.

The researchers were surprised that the number of deaths by 90 days after surgery climbed to 5.4% overall, nearly double the rate at 30 days. “This increase in the number of deaths between 30 days and 90 days after surgery was not expected and has not been extensively reported in the past, as mortality rates after surgery are traditionally examined at 30 days. The reasons for this ongoing mortality beyond 30 days are not yet clear, but deserve further investigation,” says lead author Christopher M. Pezzi, MD, Department of Surgery, Abington Health, Abington PA. The ongoing deaths between 30 and 90 days occurred at both low volume and high volume hospitals, although remained less likely at the busiest hospitals.

Other factors associated with mortality after lung surgery were anticipated, and included older age, male gender, socioeconomic factors, more advanced tumors, and a number of serious medical conditions present before the surgery. Having private insurance coverage was also associated with low (1.8%) 30-day mortality rates.

“The Impact of Annual Hospital Volume on 30-Day and Conditional 90-Day Mortality Rates for 121,099 Patients Undergoing Major Pulmonary Resection for Lung Cancer,” by Christopher M. Pezzi, MD, Katherine Mallin, PhD, Andres Samayoa Mendez, MD, E. Greer Gay, PhD, Joe B. Putnam, Jr., MD was presented at the 94th AATS Annual Meeting. April 26-30, 2014. Toronto, ON, Canada.


Story Source:

The above story is based on materials provided by American Association for Thoracic Surgery (AATS). Note: Materials may be edited for content and length.


Cite This Page:

American Association for Thoracic Surgery (AATS). "Major lung resection safer than ever, especially at the busiest hospitals." ScienceDaily. ScienceDaily, 29 April 2014. <www.sciencedaily.com/releases/2014/04/140429104950.htm>.
American Association for Thoracic Surgery (AATS). (2014, April 29). Major lung resection safer than ever, especially at the busiest hospitals. ScienceDaily. Retrieved April 22, 2015 from www.sciencedaily.com/releases/2014/04/140429104950.htm
American Association for Thoracic Surgery (AATS). "Major lung resection safer than ever, especially at the busiest hospitals." ScienceDaily. www.sciencedaily.com/releases/2014/04/140429104950.htm (accessed April 22, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Wednesday, April 22, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Teva Offers $40 Billion for Mylan

Teva Offers $40 Billion for Mylan

Reuters - Business Video Online (Apr. 21, 2015) Generic drugmaker Teva Pharmaceutical is offering $82 a share, or $40 billion, for its smaller rival Mylan, in an alternative to Mylan&apos;s deal to buy Perrigo. Bobbi Rebell reports. Video provided by Reuters
Powered by NewsLook.com
Blue Bell Recalls All Products

Blue Bell Recalls All Products

AP (Apr. 21, 2015) Blue Bell Creameries voluntary recalled for all of its products after two samples of chocolate chip cookie dough ice cream tested positive for listeria, a potentially deadly bacteria. Blue Bell&apos;s President and CEO issued a video statement. (April 21) Video provided by AP
Powered by NewsLook.com
Yemen Doctors at Breaking Point

Yemen Doctors at Breaking Point

Reuters - News Video Online (Apr. 21, 2015) A Sanaa hospital struggles to cope with the high number of casualties with severe injuries, after an air strike left at least 25 dead and hundreds wounded. Deborah Lutterbeck reports. Video provided by Reuters
Powered by NewsLook.com
'Tutu Tuesdays' Brighten Faces at Kids' Hospital

'Tutu Tuesdays' Brighten Faces at Kids' Hospital

AP (Apr. 21, 2015) Doctors and nurses have started wearing ballet tutus every Tuesday to cheer up young hospital patients at a Florida hospital. It started with a request made by a nervous patient -- now, almost the entire staff is wearing the tutus. (April 21) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins