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Rising incidence of acute pancreatitis in hospitalized children, study finds

Date:
May 7, 2014
Source:
University Hospitals Case Medical Center
Summary:
The largest investigation to date has found a significant increase in the number of acute pancreatitis cases in hospitalized children in the United States. The study looked at hospitalization records of patients 20 years old and younger using a federal children's inpatient database. From 2000 to 2009, they identified 55,012 cases of AP in hospitalized children ages 1-20.
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Thomas J. Sferra, MD, of UH Rainbow Babies & Children's Hospital, led the largest investigation to date that found a significant increase in the number of acute pancreatitis cases in hospitalized children in the United States.
Credit: UH Rainbow Babies & Children's Hospital

The largest investigation to date has found a significant increase in the number of acute pancreatitis (AP) cases in hospitalized children in the United States.

The new study, in the PLOS ONE journal found a 51 percent increase in the primary diagnosis of AP from 2000 to 2009. The number increased from 6,350 in 2000 to 9,561 in 2009.

The study looked at hospitalization records of patients 20 years old and younger using a federal children's inpatient database. From 2000 to 2009, they identified 55,012 cases of AP in hospitalized children ages 1 -- 20.

According to the study's principal investigator, Thomas J. Sferra, MD, Division Chief of Pediatric Gastroenterology, Hepatology and Nutrition at UH Rainbow Babies & Children's Hospital and Associate Professor of Pediatrics at Case Western Reserve University School of Medicine, hospitalized children with AP had longer hospital stays and higher charges. And AP was more likely to occur in children older than 5 years of age.

AP is the reversible inflammation of the pancreatic parenchyma. In children the most frequently identified causes of AP are biliary tract disease, medication adverse effect, systemic disease and trauma.

"The reason for this large increase in acute pancreatitis cases in hospitalized children is not clear," said Dr. Sferra. "Though the incidence of AP is increasing, there has been an improvement in the mortality and length of stay of these patients. These data provide a good foundation for future studies to increase our understanding of the disease."


Story Source:

The above story is based on materials provided by University Hospitals Case Medical Center. Note: Materials may be edited for content and length.


Journal Reference:

  1. Chaitanya Pant, Abhishek Deshpande, Mojtaba Olyaee, Michael P. Anderson, Anas Bitar, Marilyn I. Steele, Pat F. Bass, Thomas J. Sferra. Epidemiology of Acute Pancreatitis in Hospitalized Children in the United States from 2000–2009. PLoS ONE, 2014; 9 (5): e95552 DOI: 10.1371/journal.pone.0095552

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University Hospitals Case Medical Center. "Rising incidence of acute pancreatitis in hospitalized children, study finds." ScienceDaily. ScienceDaily, 7 May 2014. <www.sciencedaily.com/releases/2014/05/140507212253.htm>.
University Hospitals Case Medical Center. (2014, May 7). Rising incidence of acute pancreatitis in hospitalized children, study finds. ScienceDaily. Retrieved May 28, 2015 from www.sciencedaily.com/releases/2014/05/140507212253.htm
University Hospitals Case Medical Center. "Rising incidence of acute pancreatitis in hospitalized children, study finds." ScienceDaily. www.sciencedaily.com/releases/2014/05/140507212253.htm (accessed May 28, 2015).

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