Featured Research

from universities, journals, and other organizations

Study debunks common myth that urine is sterile: Bacterial differences found in urine of healthy women and women with overactive bladder

Date:
May 18, 2014
Source:
Loyola University Health System
Summary:
Bacteria live in the bladders of healthy women, discrediting the common belief that normal urine is sterile. This study also revealed that bladder bacteria in healthy women differ from the bladder bacteria in women affected by overactive bladder, which causes a sudden need to urinate.

Bacteria live in the bladders of healthy women, discrediting the common belief that normal urine is sterile. This finding was presented today by researchers from Loyola University Chicago at the 114th General Meeting of the American Society for Microbiology in Boston.

Related Articles


"Doctors have been trained to believe that urine is germ-free," said Linda Brubaker, MD, MS, co-investigator and dean, Loyola University Chicago Stritch School of Medicine (SSOM). "These findings challenge this notion, so this research opens the door to exciting new possibilities for patient treatment."

This study also revealed that bladder bacteria in healthy women differ from the bladder bacteria in women affected by overactive bladder (OAB), which causes a sudden need to urinate.

"The presence of certain bacteria in women with overactive bladder may contribute to OAB symptoms," said Evann Hilt, lead investigator and second-year master's student, Loyola University Chicago. "Further research is needed to determine if these bacterial differences are clinically relevant for the millions of women with OAB and the doctors who treat them."

Approximately 15 percent of women suffer from OAB and yet an estimated 40 -- 50 percent do not respond to conventional treatments. One possible explanation for the lack of response to medication may be the bacteria present in these women.

"If we can determine that certain bacteria cause OAB symptoms, we may be able to better identify those at risk for this condition and more effectively treat them," said Alan Wolfe, PhD, co-investigator and professor of Microbiology and Immunology, SSOM.

This study evaluated urine specimens of 90 women with and without OAB symptoms. Urine samples were collected through a catheter and analyzed using an expanded quantitative urine culture (EQUC) technique. This EQUC technique was able to find bacteria that are not identified by the standard urine culture techniques typically used to diagnose urinary tract syndromes.

"While traditional urine cultures have been the gold standard to identify urine disorders in the past, they do not detect most bacteria and have limited utility as a result," said Paul Schreckenberger, PhD, director, clinical microbiology laboratory, Loyola University Health System. "They are not as comprehensive as the EQUC protocol used in this study."

Loyola researchers now plan to determine which bacteria in the bladder are helpful and which are harmful. They also will look at how these bacteria interact with each other and with their host, and how we can use this information to help patients. This research is in line with a larger international effort that is underway to identify the core bacterial composition of a healthy human body. The goal is to correlate changes in the composition of bacterial communities in and on the body with certain diseases.


Story Source:

The above story is based on materials provided by Loyola University Health System. Note: Materials may be edited for content and length.


Cite This Page:

Loyola University Health System. "Study debunks common myth that urine is sterile: Bacterial differences found in urine of healthy women and women with overactive bladder." ScienceDaily. ScienceDaily, 18 May 2014. <www.sciencedaily.com/releases/2014/05/140518164335.htm>.
Loyola University Health System. (2014, May 18). Study debunks common myth that urine is sterile: Bacterial differences found in urine of healthy women and women with overactive bladder. ScienceDaily. Retrieved October 25, 2014 from www.sciencedaily.com/releases/2014/05/140518164335.htm
Loyola University Health System. "Study debunks common myth that urine is sterile: Bacterial differences found in urine of healthy women and women with overactive bladder." ScienceDaily. www.sciencedaily.com/releases/2014/05/140518164335.htm (accessed October 25, 2014).

Share This



More Plants & Animals News

Saturday, October 25, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Deep Sea 'mushroom' Could Be Early Branch on Tree of Life

Deep Sea 'mushroom' Could Be Early Branch on Tree of Life

Reuters - Innovations Video Online (Oct. 24, 2014) Miniature deep sea animals discovered off the Australian coast almost three decades ago are puzzling scientists, who say the organisms have proved impossible to categorise. Academics at the Natural History of Denmark have appealed to the world scientific community for help, saying that further information on Dendrogramma enigmatica and Dendrogramma discoides could answer key evolutionary questions. Jim Drury has more. Video provided by Reuters
Powered by NewsLook.com
Black Bear Cub Goes Sunday Shopping

Black Bear Cub Goes Sunday Shopping

Reuters - Light News Video Online (Oct. 23, 2014) Price check on honey? Bear cub startles Oregon drugstore shoppers. Rough Cut (no reporter narration). Video provided by Reuters
Powered by NewsLook.com
Dances With Wolves in China's Wild West

Dances With Wolves in China's Wild West

AFP (Oct. 23, 2014) One man is on a mission to boost the population of wolves in China's violence-wracked far west. The animal - symbol of the Uighur minority there - is under threat with a massive human resettlement program in the region. Duration: 00:41 Video provided by AFP
Powered by NewsLook.com
Breakfast Debate: To Eat Or Not To Eat?

Breakfast Debate: To Eat Or Not To Eat?

Newsy (Oct. 23, 2014) Conflicting studies published in the same week re-ignited the debate over whether we should be eating breakfast. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Plants & Animals

Earth & Climate

Fossils & Ruins

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins