Featured Research

from universities, journals, and other organizations

Would a diabetes drug also protect against breast cancer?

Date:
May 27, 2014
Source:
Investigación y Desarrollo
Summary:
One of the most commonly used medications to control diabetes may also have positive effects against cancer cell proliferation, as show in new research. The study examines the protective effects of metformin in the role of growth and migration of cancer cells in the body (metastasis), especially those related to breast cancer.

One of the most commonly used medications to control diabetes may also have positive effects against cancer cell proliferation, as show in research done at the Center for Research and Advanced Studies (CINVESTAV) in Mexico.

The study led by José Eduardo Pérez Salazar examines the protective effects of metformin in the role of growth and migration of cancer cells in the body (metastasis), especially those related to breast cancer.

Research in the Department of Cell Biology also analyzes the effects of oleic and linoleic acids (found in edible oils) as a kind of catalyst for the cancer cells to spread in the body.

According to Perez Salazar, it was found that cancer cells get "addicted to insulin," so in the case of overweight women with diabetes who have no control over the disease, the risk of developing breast cancer and metastasis increases.

"High insulin levels in the body are related indirectly to the formation of malignant breast tumors, but only in the case of women, in the case of men this cancer develops primarily by heredity "said the expert from the National System of Researchers.

He also explained that in Mexico there is a higher prevalence of the disease characterized by insulin resistance than for the lack of production of this hormone by the organism, meaning that the prevalence of breast cancer in women living with diabetes is higher.

However, it has been seen that women who take metformin to control insulin levels have a protective factor against breast cancer. "The drug prevents insulin resistance in the body, so that it is properly metabolized and cannot be acquired by cancer cells, which then spread across the body" said Perez Salazar.

"In people with insulin resistance, their body produces more of this hormone, which is not used and brings consequences due to the high levels of it. Metformin is what makes the receivers work better, avoiding the high levels of the hormone and this is what protecting against cancer," said the researcher.

The work done so far is based on laboratory tests using cellular tissue, but the research group at Cinvestav joined with the Juarez Hospital of Mexico City, plans to conduct tests with human tissue obtained by biopsies, therefore having greater certainty about the results. (Agencia ID)


Story Source:

The above story is based on materials provided by Investigación y Desarrollo. Note: Materials may be edited for content and length.


Cite This Page:

Investigación y Desarrollo. "Would a diabetes drug also protect against breast cancer?." ScienceDaily. ScienceDaily, 27 May 2014. <www.sciencedaily.com/releases/2014/05/140527154717.htm>.
Investigación y Desarrollo. (2014, May 27). Would a diabetes drug also protect against breast cancer?. ScienceDaily. Retrieved October 1, 2014 from www.sciencedaily.com/releases/2014/05/140527154717.htm
Investigación y Desarrollo. "Would a diabetes drug also protect against breast cancer?." ScienceDaily. www.sciencedaily.com/releases/2014/05/140527154717.htm (accessed October 1, 2014).

Share This



More Health & Medicine News

Wednesday, October 1, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Some Positive Ebola News: Outbreak 'Contained' In Nigeria

Some Positive Ebola News: Outbreak 'Contained' In Nigeria

Newsy (Sep. 30, 2014) — The CDC says a new case of Ebola has not been reported in Nigeria for more than 21 days, leading to hopes the outbreak might be nearing its end. Video provided by Newsy
Powered by NewsLook.com
UN Ebola Mission Head: Immediate Action Is Crucial

UN Ebola Mission Head: Immediate Action Is Crucial

AFP (Sep. 30, 2014) — The newly appointed head of the United Nations Mission for Ebola Emergency Response (UNMEER), Anthony Banbury, outlines operations to tackle the virus. Duration: 00:39 Video provided by AFP
Powered by NewsLook.com
CDC Confirms First Case of Ebola in US

CDC Confirms First Case of Ebola in US

AP (Sep. 30, 2014) — The CDC has confirmed the first diagnosed case of Ebola in the United States. The patient is being treated at a Dallas hospital after traveling earlier this month from Liberia. (Sept. 30) Video provided by AP
Powered by NewsLook.com
New Breast Cancer Drug Extends Lives In Clinical Trial

New Breast Cancer Drug Extends Lives In Clinical Trial

Newsy (Sep. 30, 2014) — In a clinical trial, breast cancer patients lived an average of 15 months longer when they received new drug Perjeta along with Herceptin. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins