Featured Research

from universities, journals, and other organizations

HPV testing: Benefit in primary screening

Date:
June 11, 2014
Source:
Institute for Quality and Efficiency in Health Care
Summary:
Current study results confirm the final report from 2012: Precursors of cancer can be detected earlier with HPV testing. Experts give no recommendation for a specific screening strategy, however.

The Institute for Quality and Efficiency in Health Care (IQWiG) assessed current study results on the benefit of a test for human papillomavirus (HPV) and examined whether its first assessment from January 2012 is still valid. The rapid report published by the Institute on 11 June 2014 answers this question with "yes." IQWiG still sees indications that precursors of cervical cancer can be detected and treated earlier and consequently tumours occur less often in women who underwent this testing.

Related Articles


HPV testing is not reimbursed by SHI funds

In screening for cervical cancer, the German statutory health insurance (SHI) funds currently offer an annual cytologic examination of mucosal cells from a smear taken from the neck of the womb (cervix). This test is called a Pap smear. Since it became known that infection with HPV is the main risk factor for developing cervical cancer, experts have been discussing whether HPV testing is also a suitable screening method or is even superior to a cytologic test. The SHI funds currently only reimburse HPV testing in exceptional cases, for example, in cases where the result of a Pap smear is unclear.

New analysis of large study

IQWiG conducted a new search for studies comparing primary screening strategies for cervical cancer based on different screening tests: a strategy including HPV testing alone or in combination with cytology-based testing and a strategy including cytology-based testing alone.

In this update search, they identified no studies that had not already been included in the first assessment. However, they were now able to include the final analysis of one of the largest studies (POBASCAM), for which only an interim analysis had been available in 2011.

Fewer cancer diagnoses in the second screening round

Also under inclusion of the new data, the number of diagnoses for invasive cervical cancer in the second screening round was lower in the HPV group than in the group of women who had only been examined with a cytology-based screening strategy (e.g. Pap smear) in the first screening round. This also applies to the so-called "composite outcome," which not only comprised tumours, but also advanced precursors of cancer. IQWiG therefore determined an indication of a benefit in each case.

There are still no data or no evaluable data available on mortality, quality of life and potential harm.

As the screening strategies applied in the studies varied greatly and could therefore not be compared with each other, the results still do not allow a recommendation for a specific screening strategy in the German health care system.


Story Source:

The above story is based on materials provided by Institute for Quality and Efficiency in Health Care. Note: Materials may be edited for content and length.


Cite This Page:

Institute for Quality and Efficiency in Health Care. "HPV testing: Benefit in primary screening." ScienceDaily. ScienceDaily, 11 June 2014. <www.sciencedaily.com/releases/2014/06/140611102207.htm>.
Institute for Quality and Efficiency in Health Care. (2014, June 11). HPV testing: Benefit in primary screening. ScienceDaily. Retrieved December 25, 2014 from www.sciencedaily.com/releases/2014/06/140611102207.htm
Institute for Quality and Efficiency in Health Care. "HPV testing: Benefit in primary screening." ScienceDaily. www.sciencedaily.com/releases/2014/06/140611102207.htm (accessed December 25, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Thursday, December 25, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

FDA Issues New Warning About Pure Caffeine Powder Usage

FDA Issues New Warning About Pure Caffeine Powder Usage

Newsy (Dec. 24, 2014) The FDA cites two deaths this year linked to pure caffeine powder as warnings of the potentially fatal substance. Video provided by Newsy
Powered by NewsLook.com
Alarming CDC Lab Report Reveals Ebola Sample Mix-Up

Alarming CDC Lab Report Reveals Ebola Sample Mix-Up

Newsy (Dec. 24, 2014) The Centers for Disease Control and Prevention released a report claiming a lab tech in Atlanta might have been exposed to the Ebola virus. Video provided by Newsy
Powered by NewsLook.com
French General Physicians Begin Strike, ER Doctors Back to Work

French General Physicians Begin Strike, ER Doctors Back to Work

AFP (Dec. 23, 2014) French doctors went on strike Tuesday in protest at an upcoming health bill. Emergency room doctors on the other end are returning to work after reaching an historic agreement. Duration: 01:17 Video provided by AFP
Powered by NewsLook.com
Malpractice Suit Changes Rule for Cruise Ships

Malpractice Suit Changes Rule for Cruise Ships

AP (Dec. 23, 2014) A recent court ruling may have opened the courthouse door for cruise ship passengers who claim poor treatment by ship medical personnel. (Dec. 23) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins