Featured Research

from universities, journals, and other organizations

No evidence that soy food protects against endometrial cancer, study finds

Date:
June 18, 2014
Source:
Wiley
Summary:
No evidence of a protective association between soy food and endometrial cancer risk has been found, concludes a new study. Soy foods are an almost exclusive dietary source of isoflavones, a plant-derived estrogen. Some studies have highlighted their potential cancer protective properties, however, research looking at the link to endometrial cancer has been inconsistent.

Researchers have found no evidence of a protective association between soy food and endometrial cancer risk, says a new study published (18 June) in BJOG: An International Journal of Obstetrics and Gynaecology.

Soy foods are an almost exclusive dietary source of isoflavones, a plant-derived estrogen. Some studies have highlighted their potential cancer protective properties, however, research looking at the link to endometrial cancer has been inconsistent.

The study defined short IPI as time from the immediate preceding birth to subsequent birth of the index pregnancy of <6 months, 6 to <12 months, and 12 to <18 months. Researchers categorized the women with short IPIs into two groups, IPI less than 12 months and IPI 12-18 months, comparing them to women who were considered to have an optimal IPI of 18 months or more.

The food questionnaire specifically asked about the consumption of 8 soy food items such as miso soup, tofu and soymilk. Researchers then looked at the total dietary intake of genistein and daidzein, different types of isoflavones.

The women were divided into three groups according to the intake of soy foods and isoflavones. In the follow up, 112 women were diagnosed with endometrial cancer.

Women consuming more isoflavones were older, less likely to be current smokers, alcohol and regular coffee drinkers, and more likely to have a history of diabetes. They also had a higher dietary intake of fruit and vegetables.

Looking specifically at tofu, miso soup and soy food, the researchers found no association with endometrial cancer. Neither higher consumption of total soy foods nor isoflavones were associated with the risk of endometrial cancer after adjustment for factors such as age, alcohol consumption, smoking, BMI, menopausal status, coffee intake and number of deliveries.

Dr Motoki Iwasaki, Epidemiology Division, Epidemiology and Prevention Group, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan and co-author said:

"Our study found that intake of soy and isoflavones were not associated with the risk of endometrial cancer.

"Although the incidence of endometrial cancer is much lower in Asian countries, the incidence rate has been increasing. We also know that the consumption of soy foods among Japanese people is very high.

"We need further studies with a greater number of cases to verify these findings and add to the research base."

John Thorp, BJOG Deputy-Editor-in-Chief, said:

"This large population-based study found no evidence of a protective association of soy food or isoflavone intake and previous studies have been inconsistent.

"Confirmation of these results needs further investigation and larger more diverse studies."


Story Source:

The above story is based on materials provided by Wiley. Note: Materials may be edited for content and length.


Journal Reference:

  1. S Budhathoki, M Iwasaki, N Sawada, T Yamaji, T Shimazu, S Sasazuki, M Inoue, S Tsugane. Soy food and isoflavone intake and endometrial cancer risk: the Japan Public Health Center-based prospective study. BJOG: An International Journal of Obstetrics & Gynaecology, 2014; DOI: 10.1111/1471-0528.12853

Cite This Page:

Wiley. "No evidence that soy food protects against endometrial cancer, study finds." ScienceDaily. ScienceDaily, 18 June 2014. <www.sciencedaily.com/releases/2014/06/140618072039.htm>.
Wiley. (2014, June 18). No evidence that soy food protects against endometrial cancer, study finds. ScienceDaily. Retrieved October 21, 2014 from www.sciencedaily.com/releases/2014/06/140618072039.htm
Wiley. "No evidence that soy food protects against endometrial cancer, study finds." ScienceDaily. www.sciencedaily.com/releases/2014/06/140618072039.htm (accessed October 21, 2014).

Share This



More Health & Medicine News

Tuesday, October 21, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

How Nigeria Beat Its Ebola Outbreak

How Nigeria Beat Its Ebola Outbreak

Newsy (Oct. 20, 2014) The World Health Organization has declared Nigeria free of Ebola. Health experts credit a bit of luck and the government's initial response. Video provided by Newsy
Powered by NewsLook.com
Another Study Suggests Viagra Is Good For The Heart

Another Study Suggests Viagra Is Good For The Heart

Newsy (Oct. 20, 2014) An ingredient in erectile-dysfunction medications such as Viagra could improve heart function. Perhaps not surprising, given Viagra's history. Video provided by Newsy
Powered by NewsLook.com
Ebola Worries End for Dozens on U.S. Watch Lists

Ebola Worries End for Dozens on U.S. Watch Lists

Reuters - US Online Video (Oct. 20, 2014) Forty-three people who had contact with Thomas Eric Duncan, the first person diagnosed with Ebola in the U.S., were cleared overnight of twice-daily monitoring after 21 days of showing no symptoms. Rough Cut (no reporter narration). Video provided by Reuters
Powered by NewsLook.com
CDC Calls for New Ebola Safety Guidelines

CDC Calls for New Ebola Safety Guidelines

AP (Oct. 20, 2014) Centers for Disease Control and Prevention Director Dr. Tom Frieden laid out new guidelines for health care workers when dealing with the deadly Ebola virus including new precautions when taking off personal protective equipment. (Oct. 20) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins