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Revisions needed for current IV feeding safeguards against bloodstream infections

Date:
June 26, 2014
Source:
American Society for Parenteral and Enteral Nutrition (A.S.P.E.N.)
Summary:
Current guidelines to help prevent bloodstream infections during intravenous feeding may need revisions to strengthen protections for patients, a new study finds. The study found that additional factors, including glucose concentration, proportion of glucose to lipid, and osmolarity (concentration of a solution that can pass through the wall of a living cell through osmosis), can affect microbial growth apart from the presence of lipids.

Current guidelines to help prevent bloodstream infections during intravenous feeding may need revisions to strengthen protections for patients, a new study finds.

Researchers at the United Kingdom's University of Southampton found that current guidelines do not account for other independent factors that can affect the growth of potentially deadly microorganisms. Their study was published today in the OnlineFirst version of the Journal of Parenteral and Enteral Nutrition (JPEN), the research journal of the American Society for Parenteral and Enteral Nutrition (A.S.P.E.N.).

Existing guidelines restrict how long a single bag of parenteral nutrition (PN) containing lipids can be used due to the ability of lipids to encourage the growth of microorganisms. This study looked at the growth of Escherichia coli (E coli) and Enterococcus durans (E durans) in PN to see if other factors can affect microbial growth.

The study found that additional factors, including glucose concentration, proportion of glucose to lipid, and osmolarity (concentration of a solution that can pass through the wall of a living cell through osmosis), can affect microbial growth apart from the presence of lipids.

The study's researchers recommend that these additional factors should be considered when making clinical and policy decisions to limit the potential growth of microorganisms in PN.


Story Source:

The above story is based on materials provided by American Society for Parenteral and Enteral Nutrition (A.S.P.E.N.). Note: Materials may be edited for content and length.


Journal Reference:

  1. P. D. Austin, K. S. Hand, M. Elia. Factors Influencing Escherichia coli and Enterococcus durans Growth in Parenteral Nutrition With and Without Lipid Emulsion to Inform Maximum Duration of Infusion Policy Decisions. Journal of Parenteral and Enteral Nutrition, 2014; DOI: 10.1177/0148607114538456

Cite This Page:

American Society for Parenteral and Enteral Nutrition (A.S.P.E.N.). "Revisions needed for current IV feeding safeguards against bloodstream infections." ScienceDaily. ScienceDaily, 26 June 2014. <www.sciencedaily.com/releases/2014/06/140626101704.htm>.
American Society for Parenteral and Enteral Nutrition (A.S.P.E.N.). (2014, June 26). Revisions needed for current IV feeding safeguards against bloodstream infections. ScienceDaily. Retrieved July 28, 2014 from www.sciencedaily.com/releases/2014/06/140626101704.htm
American Society for Parenteral and Enteral Nutrition (A.S.P.E.N.). "Revisions needed for current IV feeding safeguards against bloodstream infections." ScienceDaily. www.sciencedaily.com/releases/2014/06/140626101704.htm (accessed July 28, 2014).

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