Featured Research

from universities, journals, and other organizations

Risk factors for chronic kidney disease are present decades before diagnosis

Date:
June 26, 2014
Source:
American Society of Nephrology (ASN)
Summary:
Risk factors for chronic kidney disease (CKD) are present and identifiable 30 years before diagnosis, according to a new study. The findings suggest avenues for future research to determine whether certain early interventions can prevent future kidney disease.

Risk factors for chronic kidney disease (CKD) are present and identifiable 30 years before diagnosis, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN). The findings suggest avenues for future research to determine whether certain early interventions can prevent future kidney disease.

Related Articles


Approximately 60 million people globally have CKD. Caroline S. Fox, MD MPH, Gearoid McMahon, MB, BCh (National Heart Lung and Blood Institute's Framingham Heart Study and the Center for Population Studies), and their colleagues investigated whether CKD risk factors might be present decades before the diagnosis of CKD. "One of the benefits of the Framingham Heart Study is that we have a very long duration of follow-up. As a result, we are able to look far back in time prior to when individuals develop a disease to examine their risk factors," said Dr. Fox.

The researchers identified 441 new cases of CKD among participants of the Framingham Heart Study, and they matched them with 882 controls who did not develop CKD. Those who ultimately developed CKD were 76% more likely to have had hypertension, 71% more likely to have been obese, and 43% more likely to have had higher triglycerides 30 years before CKD diagnosis. They were also 38% more likely to have had hypertension, 35% more likely to have had higher triglyceride levels, and nearly 3-times more likely to have had diabetes 20 years before CKD diagnosis. The more risk factors an individual had in the past, the more likely they were to develop CKD.

"This research shows that these risk factors are present long before the disease is diagnosed. This is important because it suggests that we should be addressing these risk factors earlier in life to potentially prevent future disease," said Dr. McMahon.


Story Source:

The above story is based on materials provided by American Society of Nephrology (ASN). Note: Materials may be edited for content and length.


Journal Reference:

  1. G. M. McMahon, S. R. Preis, S.-J. Hwang, C. S. Fox. Mid-Adulthood Risk Factor Profiles for CKD. Journal of the American Society of Nephrology, 2014; DOI: 10.1681/ASN.2013070750

Cite This Page:

American Society of Nephrology (ASN). "Risk factors for chronic kidney disease are present decades before diagnosis." ScienceDaily. ScienceDaily, 26 June 2014. <www.sciencedaily.com/releases/2014/06/140626172707.htm>.
American Society of Nephrology (ASN). (2014, June 26). Risk factors for chronic kidney disease are present decades before diagnosis. ScienceDaily. Retrieved April 18, 2015 from www.sciencedaily.com/releases/2014/06/140626172707.htm
American Society of Nephrology (ASN). "Risk factors for chronic kidney disease are present decades before diagnosis." ScienceDaily. www.sciencedaily.com/releases/2014/06/140626172707.htm (accessed April 18, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Saturday, April 18, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Our Love Of Puppy Dog Eyes Explained By Science

Our Love Of Puppy Dog Eyes Explained By Science

Newsy (Apr. 17, 2015) Researchers found a spike in oxytocin occurs in both humans and dogs when they gaze into each other&apos;s eyes. Video provided by Newsy
Powered by NewsLook.com
Scientists Find Link Between Gestational Diabetes And Autism

Scientists Find Link Between Gestational Diabetes And Autism

Newsy (Apr. 17, 2015) Researchers who analyzed data from over 300,000 kids and their mothers say they&apos;ve found a link between gestational diabetes and autism. Video provided by Newsy
Powered by NewsLook.com
Video Messages Help Reassure Dementia Patients

Video Messages Help Reassure Dementia Patients

AP (Apr. 17, 2015) Family members are prerecording messages as part of a unique pilot program at the Hebrew Home in New York. The videos are trying to help victims of Alzheimer&apos;s disease and other forms of dementia break through the morning fog of forgetfulness. (April 17) Video provided by AP
Powered by NewsLook.com
Boy or Girl? Intersex Awareness Is on the Rise

Boy or Girl? Intersex Awareness Is on the Rise

AP (Apr. 17, 2015) At least 1 in 5,000 U.S. babies are born each year with intersex conditions _ ambiguous genitals because of genetic glitches or hormone problems. Secrecy and surgery are common. But some doctors and activists are trying to change things. (April 17) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins