Featured Research

from universities, journals, and other organizations

Genetics the dominant risk factor in common cancers

Date:
June 27, 2014
Source:
Lund University
Summary:
A study of individuals who have been adopted has identified genetics as the dominant risk factor in ‘familial’ breast, prostate and colorectal cancers. Researchers have presented the new research findings based on studies of population registers.“The results of our study do not mean that an individual’s lifestyle is not important for the individual’s risk of developing cancer, but it suggests that the risk for the three most common types of cancer is dependent to a greater extent on genetics”, said the lead of the study.

A study of individuals who have been adopted has identified genetics as the dominant risk factor in 'familial' breast, prostate and colorectal cancers.

Researchers at the Centre for Primary Health Care Research at Lund University and Region Skĺne in Sweden have presented the new research findings based on studies of population registers.

"The results of our study do not mean that an individual's lifestyle is not important for the individual's risk of developing cancer, but it suggests that the risk for the three most common types of cancer is dependent to a greater extent on genetics," said Bengt Zöller, a reader at Lund University who led the study.

The researchers studied adoptees born in Sweden in relation to both their biological parents and their adoptive parents. The Swedish multi-generation register and the cancer register were used to monitor 70 965 adopted men and women. They were all born between 1932 and 1969 and developed breast cancer, prostate cancer or colorectal cancer between the years 1958 and 2010. Using register studies, the researchers also looked at their adoptive and biological parents over the same period.

The risk of cancer in adoptees with at least one biological parent who had had the same cancer was 80-100 per cent higher for breast cancer, prostate cancer and colorectal cancer than for a control group without a biological parent with the same cancer. There was, however, no higher risk for individuals with adoptive parents affected by breast cancer, prostate cancer or colorectal cancer than for a control group. Individuals with a biological parent with cancer also developed the disease at a younger age than those without a biological parent with the same cancer. The age at which an individual developed cancer was not, however, affected by whether an adoptive parent had had the same cancer.

The results are an important indicator of the significance of hereditary factors for breast, prostate and colorectal cancer, according to Bengt Zöller.

"The occurrence of breast cancer, prostate cancer and colorectal cancer in biological parents is an important risk factor that should be included in patients' medical history and examinations. It is therefore important that doctors ask about family history so that they can decide whether further tests are needed," said Bengt Zöller.


Story Source:

The above story is based on materials provided by Lund University. Note: Materials may be edited for content and length.


Journal Reference:

  1. Bengt Zöller, Xinjun Li, Jan Sundquist, Kristina Sundquist. Familial transmission of prostate, breast and colorectal cancer in adoptees is related to cancer in biological but not in adoptive parents: A nationwide family study. European Journal of Cancer, 2014; DOI: 10.1016/j.ejca.2014.05.018

Cite This Page:

Lund University. "Genetics the dominant risk factor in common cancers." ScienceDaily. ScienceDaily, 27 June 2014. <www.sciencedaily.com/releases/2014/06/140627094410.htm>.
Lund University. (2014, June 27). Genetics the dominant risk factor in common cancers. ScienceDaily. Retrieved September 30, 2014 from www.sciencedaily.com/releases/2014/06/140627094410.htm
Lund University. "Genetics the dominant risk factor in common cancers." ScienceDaily. www.sciencedaily.com/releases/2014/06/140627094410.htm (accessed September 30, 2014).

Share This



More Health & Medicine News

Tuesday, September 30, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

How 'Yes Means Yes' Defines Sexual Assault

How 'Yes Means Yes' Defines Sexual Assault

Newsy (Sep. 29, 2014) — Aimed at reducing sexual assaults on college campuses, California has adopted a new law changing the standard of consent for sexual activity. Video provided by Newsy
Powered by NewsLook.com
Scientists May Have Found An Early Sign Of Pancreatic Cancer

Scientists May Have Found An Early Sign Of Pancreatic Cancer

Newsy (Sep. 29, 2014) — Researchers looked at 1,500 blood samples and determined people who developed pancreatic cancer had more branched chain amino acids. Video provided by Newsy
Powered by NewsLook.com
Colo. Doctors See Cluster of Enterovirus Cases

Colo. Doctors See Cluster of Enterovirus Cases

AP (Sep. 29, 2014) — Doctors at the Children's Hospital of Colorado say they have treated over 4,000 children with serious respiratory illnesses since August. Nine of the patients have shown distinct neurological symptoms, including limb weakness. (Sept. 29) Video provided by AP
Powered by NewsLook.com
Dr.'s Unsure of Cause of Fast-Spreading Virus

Dr.'s Unsure of Cause of Fast-Spreading Virus

AP (Sep. 29, 2014) — Doctors at the Children's Hospital of Colorado say they have treated over 4,000 children with serious respiratory illnesses since August. Nine of the patients have shown distinct neurological symptoms, including limb weakness. (Sept. 29) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins