Featured Research

from universities, journals, and other organizations

Saltier intravenous fluids reduce complications from surgery, study shows

Date:
July 15, 2014
Source:
Thomas Jefferson University
Summary:
Infusing a saltier saline solution during and after surgery decreases overall complication rate for a complex procedure, research shows. “This relatively minor change in intravenous fluids has had a tremendous effect on the overall complication rate for our patients,” says the first author. “Based on these findings we have already changed our practice in the operating room to use hypertonic saline.”

Adequate hydration via a saline drip is essential during surgery, but recent reports suggest that getting the balance of salt and water just right could have an important impact on patient recovery. In the largest study of its kind researchers at Thomas Jefferson University found that a slightly saltier intravenous drip (hypertonic saline), and lower total volume of fluid received, reduced the overall rate of complications by 25 percent after the complex Whipple surgery for pancreatic cancer.

Related Articles


"This relatively minor change in intravenous fluids has had a tremendous effect on the overall complication rate for our patients," says first author Harish Lavu, M.D., Associate Professor of Surgery at Thomas Jefferson University. "Based on these findings we have already changed our practice in the operating room to use hypertonic saline," he added.

Saline delivered intravenously during and after surgery helps to maintain a patient's fluid balance and blood pressure within the appropriate range. The increased salt concentration in the hypertonic saline is designed to keep the body in equilibrium by helping to reduce fluid buildup in the lungs, interstitial spaces and swelling in the extremities.

The hypertonic saline draws out the excess fluid that builds up in these tissues. "Too much swelling can compromise the delivery of blood and oxygen to the organs. That reduction can slow the healing process," says Dr. Lavu.

The current study is the largest of its kind and shows a benefit when hypertonic saline is used for the Whipple operation, which can take from to 5-9 hours to perform. Patients undergoing this operation for pancreatic cancer can have complications such as blood clots, pneumonia, wound infection, urinary tract infections, and others.

A total of 264 patients were enrolled in the study, with 128 receiving standard fluid and 131 receiving a hypertonic saline solution. By examining all of the complications together, the researchers found a 25 percent reduction in overall complications in the group that received hypertonic saline. In absolute numbers, 93 patients in the hypertonic group had complications, compared with 123 patients in the standard fluid group.

"We are confident that this change in our surgical process will help our patients recover faster with fewer complications," says senior author Charles J. Yeo, M.D., The Samuel D. Gross Professor and Chair of the Department of Surgery at Thomas Jefferson University.


Story Source:

The above story is based on materials provided by Thomas Jefferson University. Note: Materials may be edited for content and length.


Cite This Page:

Thomas Jefferson University. "Saltier intravenous fluids reduce complications from surgery, study shows." ScienceDaily. ScienceDaily, 15 July 2014. <www.sciencedaily.com/releases/2014/07/140715141357.htm>.
Thomas Jefferson University. (2014, July 15). Saltier intravenous fluids reduce complications from surgery, study shows. ScienceDaily. Retrieved October 24, 2014 from www.sciencedaily.com/releases/2014/07/140715141357.htm
Thomas Jefferson University. "Saltier intravenous fluids reduce complications from surgery, study shows." ScienceDaily. www.sciencedaily.com/releases/2014/07/140715141357.htm (accessed October 24, 2014).

Share This



More Health & Medicine News

Friday, October 24, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

IKEA Desk Converts From Standing to Sitting With One Button

IKEA Desk Converts From Standing to Sitting With One Button

Buzz60 (Oct. 24, 2014) IKEA is out with a new convertible desk that can convert from a sitting desk to a standing one with just the push of a button. Jen Markham explains. Video provided by Buzz60
Powered by NewsLook.com
Ebola Protective Suits Being Made in China

Ebola Protective Suits Being Made in China

AFP (Oct. 24, 2014) A factory in China is busy making Ebola protective suits for healthcare workers and others fighting the spread of the virus. Duration: 00:38 Video provided by AFP
Powered by NewsLook.com
WHO: Millions of Ebola Vaccine Doses by 2015

WHO: Millions of Ebola Vaccine Doses by 2015

AP (Oct. 24, 2014) The World Health Organization said on Friday that millions of doses of two experimental Ebola vaccines could be ready for use in 2015 and five more experimental vaccines would start being tested in March. (Oct. 24) Video provided by AP
Powered by NewsLook.com
Doctor in NYC Quarantined With Ebola

Doctor in NYC Quarantined With Ebola

AP (Oct. 24, 2014) An emergency room doctor who recently returned to the city after treating Ebola patients in West Africa has tested positive for the virus. He's quarantined in a hospital. (Oct. 24) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins