Featured Research

from universities, journals, and other organizations

High-intensity exercise found safe and effective in long-term heart transplant, study concludes

Date:
August 18, 2014
Source:
Wiley
Summary:
High-intensity exercise can help stable heart transplant patients reach higher levels of exercise capacity, and gain better control of their blood pressure than moderate intensity exercise, investigators report. Their research shows that high-intensity interval exercise -— training for a few minutes at close to the maximum heart rate -— is safe and more efficient than moderate exercise for improving exercise capacity in different groups of patients with heart disease.

High-intensity exercise can help stable heart transplant patients reach higher levels of exercise capacity, and gain better control of their blood pressure than moderate intensity exercise, investigators report in a new study published in the American Journal of Transplantation.

Related Articles


Recent research shows that high-intensity interval exercise -- training for a few minutes at close to the maximum heart rate -- is safe and more efficient than moderate exercise for improving exercise capacity in different groups of patients with heart disease. Researchers led by Christian Dall, PhD fellow, MSc, of the Bispebjerg Hospital at the University of Copenhagen, Denmark, investigated whether people who have received a new heart gain similar benefits from high-intensity interval training, or whether they should exercise at moderate intensity as currently recommended.

The team compared the effects of 12 weeks of high-intensity interval training versus continued moderate training in 16 stable heart transplant recipients who had been living with their new heart for more than one year.

The trial revealed that high-intensity interval training is safe in heart transplant patients, and the effect on exercise capacity and blood pressure control is superior to moderate intensity training. VO2 max, or maximal oxygen uptake, increased by 17 percent in patients performing high-intensity interval training compared with 10 percent in patients performing continued moderate training. Systolic blood pressure decreased significantly in patients in the high-intensity group, while it remained unchanged in patients in the moderate intensity group. Peak heart rate also increased in the high-intensity group but not in the moderate intensity group. Heart rate recovery improved in both groups.

"Today, people who have been given a new heart experience increased physical function, quality of life, and overall life span; however, most patients continue to have limitations in their physical function and reduced quality of life compared to the general population due to side-effects from anti-rejection medications and because heart rate regulation is impaired after heart transplantation," said Dall. "The impaired heart rate response has been considered a hindrance for more demanding high-intensity training, but this new study documents that stable heart transplant recipients benefit from this type of training more than from the moderate training that has been recommended so far. Importantly, the training is also safe and well received by patients."

The findings may be especially encouraging for athletes who compete in the Transplant Games of America, whose most recent event was held earlier this month in Houston, and those training for upcoming summer and winter World Transplant Games.

In an accompanying report, investigators provide a summary of a two-day meeting held in April 2013 in Toronto, Canada, in which a group of clinicians, researchers, administrators, and patient representatives discussed key issues related to exercise in organ transplant recipients. The attendees developed a list of top research priorities and a research agenda for exercise in solid organ transplant, which includes the need to conduct large multicenter intervention studies, standardize measures of physical function in clinical trials, examine the benefits of novel types of exercise, and assess the effects of exercise on measures such as immunity, infection, and cognition.


Story Source:

The above story is based on materials provided by Wiley. Note: Materials may be edited for content and length.


Journal Reference:

  1. Christian H. Dall, Martin Snoer, Stefan Christensen, Tea Monk-Hansen, Marianne Frederiksen, Finn Gustafsson, Henning Langberg, and Eva Prescott. Effect of High-Intensity Training Versus Moderate Training on Peak Oxygen Uptake and Chronotropic Response in Heart Transplant Recipients: A Randomized Crossover Trial. American Journal of Transplantation, August 2014 DOI: 10.1111/ajt.12873

Cite This Page:

Wiley. "High-intensity exercise found safe and effective in long-term heart transplant, study concludes." ScienceDaily. ScienceDaily, 18 August 2014. <www.sciencedaily.com/releases/2014/08/140818012246.htm>.
Wiley. (2014, August 18). High-intensity exercise found safe and effective in long-term heart transplant, study concludes. ScienceDaily. Retrieved December 18, 2014 from www.sciencedaily.com/releases/2014/08/140818012246.htm
Wiley. "High-intensity exercise found safe and effective in long-term heart transplant, study concludes." ScienceDaily. www.sciencedaily.com/releases/2014/08/140818012246.htm (accessed December 18, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Thursday, December 18, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

UN: Up to One Million Facing Hunger in Ebola-Hit Countries

UN: Up to One Million Facing Hunger in Ebola-Hit Countries

AFP (Dec. 17, 2014) Border closures, quarantines and crop losses in West African nations battling the Ebola virus could lead to as many as one million people going hungry, UN food agencies said on Wednesday. Duration: 00:52 Video provided by AFP
Powered by NewsLook.com
When You Lose Weight, This Is Where The Fat Goes

When You Lose Weight, This Is Where The Fat Goes

Newsy (Dec. 17, 2014) Can fat disappear into thin air? New research finds that during weight loss, over 80 percent of a person's fat molecules escape through the lungs. Video provided by Newsy
Powered by NewsLook.com
Why Your Boss Should Let You Sleep In

Why Your Boss Should Let You Sleep In

Newsy (Dec. 17, 2014) According to research out of the University of Pennsylvania, waking up for work is the biggest factor that causes Americans to lose sleep. Video provided by Newsy
Powered by NewsLook.com
Flu Outbreak Closing Schools in Ohio

Flu Outbreak Closing Schools in Ohio

AP (Dec. 17, 2014) A wave of flu illnesses has forced some Ohio schools to shut down over the past week. State officials confirmed one pediatric flu-related death, a 15-year-old girl in southern Ohio. (Dec. 17) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins