Vioxx News
February 9, 2016

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updated 7:52pm EST

More Vioxx News
February 9, 2016

Separating a Cancer Prevention Drug from Heart Disease Risk

Sep. 13, 2011 — Celecoxib reduces the risk of developing precancerous colon polyps, at the cost of increased heart disease risk. By looking closely at how celecoxib acts in the cell, it may be possible to get the ... read more

Why Drugs Increase Risk of Heart Attacks and Strokes: Analysis Highlights Cardiovascular Risk of Fluid Retention

Feb. 22, 2011 — New research shows that medications which have raised safety concerns over heart attack and stroke risks may not have gotten approval from the US Food and Drug Administration if the cardiovascular ... read more

Celecoxib (Celebrex) May Be Effective in Preventing Non-Melanoma Skin Cancers

Nov. 29, 2010 — Celecoxib (also known by its brand name Celebrex) may help prevent non-melanoma skin cancers in patients with extensive actinic keratosis, which is often a precursor to these cancers, according to a ... read more

Link Between Arthritis Pain Reliever and Cardiovascular Events Discovered

Sep. 13, 2010 — Researchers have discovered a novel mechanism as to why the long-term, high-dosage use of the well-known arthritis pain medication, Vioxx, led to heart attacks and strokes. Their groundbreaking ... read more

Can Celebrex Prevent Cancer-Causing Colon Polyps?

May 13, 2010 — Researchers are testing whether celecoxib, known by its brand name Celebrex, can help prevent the growth of precancerous polyps that form in the colon, rectum and small intestine of children with an ... read more

Painkiller Undermines Aspirin's Anti-Clotting Action

Dec. 14, 2009 — Millions of Americans take Celebrex for arthritis or other pain. Many, if they are middle-aged or older, also take a low-dose aspirin tablet daily to reduce the risk of heart attack and stroke. Yet ... read more

Vioxx Trial Data Shows Early Cardiovascular Risk

Nov. 23, 2009 — Evidence of cardiovascular risks associated with taking Vioxx, the popular, nonsteroidal anti-inflammatory drug (rofecoxib), could have been identified nearly four years before its manufacturer, ... read more

Discovery In Colon Cancer Prevention

May 18, 2009 — A new study finds that individuals who have low expression of the "Celebrex gene," 15-PGDH, are actually resistant to Celebrex treatment when used to prevent colon ... read more

Potential Lung Disease Biomarkers Yield Clues To COX-2 Inhibitor Side Effects

Apr. 29, 2009 — In searching for a simple way to identify individuals with smoking-related lung injury, scientists at have stumbled upon a potential explanation for why the class of pain-relievers known as COX-2 ... read more

Prostaglandin Receptor Key To Atherosclerosis Development

Dec. 15, 2008 — Atherosclerosis -- a disease that includes the buildup of fatty, cholesterol-laden lumps of cells inside the artery wall -- is the underlying cause of heart attacks and strokes. Researchers have now ... read more

Prostate Cancer Can Be Halted With Anti-Inflammatory And Statin Used In Tandem, Study Suggests

Apr. 14, 2008 — Researchers have shown that administering a combination of the widely used drugs Celebrex (celecoxib, a nonsteroidal anti-inflammatory drug) and Lipitor (atorvastatin, a cholesterol lowering drug) ... read more

Potential New Drug Targets Against Hormone-Dependent Breast Cancer Identified

Feb. 28, 2008 — The identification of two cellular receptors that likely contribute to the genesis of hormone-dependent breast cancer points the way to new, highly targeted therapies against the disease. The finding ... read more

Popular Arthritis Drug May Disrupt Heart Rhythm, New Research Finds

Jan. 24, 2008 — Celebrex, a popular arthritis drug that blocks pain by inhibiting an enzyme known as COX-2, has been shown in laboratory studies to induce arrhythmia, or irregular beating of the heart, via a novel ... read more

Jan. 14, 2008 — COX-2 inhibitors like Celecoxib have come under scrutiny lately due to adverse cardiovascular side-effects stemming from COX-2 reduction. In both fruit fly and rat models, researchers reveal another ... read more

Vioxx Side-Effects: Possible Explanation

Aug. 27, 2007 — Vioxx and related pain medications were taken off the market in 2004 because they caused dangerous heart problems in some people. Scientists may now have figured out how these drugs trigger these ... read more

Celecoxib Helps Prevent Restenosis And Appears Safe

Aug. 18, 2007 — Adjunctive use of the COX-2 inhibitor celcoxib after stent implantation in patients with coronary artery disease appears safe and can reduce the need for revascularisation of the target lesion, ... read more

Researcher Lays Out Benefits Of Aspirin To Prevent Colon Cancer

May 23, 2007 — A colon cancer researcher has laid out in a recent article how he thinks medical science should employ aspirin and new aspirin-like drugs for use in preventing colon cancer in certain high-risk ... read more

Combining NSAIDs With Chemotherapy, Radiation May Improve Cancer Treatment

May 17, 2007 — Certain nonsteroidal anti-inflammatory drugs may be better suited to treating cancer, in combination with standard therapies, rather than preventing it, according to new ... read more

FDA Causes Unnecessary Scare About Common Painkillers, Says Doctor

Apr. 24, 2007 — The US Food and Drug Administration has caused an unnecessary scare about some pain relievers by adding a warning to drugs that are safe, says Curt Furberg, M.D., Ph.D., from Wake Forest University ... read more

Green Tea And COX-2 Inhibitors Combine To Slow Growth Of Prostate Cancer

Mar. 1, 2007 — Drinking a nice warm cup of green tea has long been touted for its healthful benefits, both real and anecdotal. But now researchers have found that a component of green tea, combined with low doses ... read more

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