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Celecoxib Can Adversely Affect Heart Rhythm, Study Suggests
COX-2 inhibitors like
Celecoxib have come under
scrutiny lately due to
adverse cardiovascular
side-effects stemming from
COX-2 reduction. In both
... > full story
New understanding of COX-1 and COX-2 enzymes could revise classification of pain meds
COX-1 and COX-2 enzymes may
be blocked by pain
medications such as Advil
and Vioxx in a more complex
manner than was previously
... > full story
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Popular Arthritis Drug May Disrupt Heart Rhythm, New Research Finds
January 25, 2008 — Celebrex, a popular arthritis drug that blocks pain by inhibiting an enzyme known as COX-2, has been shown in laboratory studies to induce arrhythmia, or irregular beating of the heart, via a novel ... > full story -
Vioxx Side-effects: Possible Explanation
August 29, 2007 — Vioxx and related pain medications were taken off the market in 2004 because they caused dangerous heart problems in some people. Scientists may now have figured out how these drugs trigger these ... > full story -
FDA Causes Unnecessary Scare About Common Painkillers, Says Doctor
April 25, 2007 — The US Food and Drug Administration has caused an unnecessary scare about some pain relievers by adding a warning to drugs that are safe, says Curt Furberg, M.D., Ph.D., from Wake Forest University ... > full story -
Engineering The 'Super Enzyme' -- A Potential New Weapon Against Heart Disease
November 28, 2006 — Efforts to understand the link between the cyclooxygenase-2 (COX-2) inhibitor arthritis drugs and heart disease have had an unanticipated benefit in leading to development of an engineered protein ... > full story -
Celecoxib, Naproxen Safety Results Now Published
November 20, 2006 — A paper appearing this week in the Public Library of Science journal PLoS Clinical Trials presents findings from a large National Institutes of Health sponsored trial regarding the cardiovascular and ... > full story -
New Evidence On Risks Associated With Cox-2 Inhibitors And NSAIDs
September 18, 2006 — Two new review studies evaluating the safety of the pain-relieving medications selective cyclooxygenase 2 (COX-2) inhibitors and non-steroidal anti-inflammatory drugs (NSAIDs) find increased ... > full story -
New Type Of Pain Reliever May Benefit The Heart
September 13, 2006 — Researchers at the University of Pennsylvania School of Medicine have found that deleting an inflammation enzyme in a mouse model of heart disease slowed the development of atherosclerosis. What's ... > full story -
Pest Control Research Leads To Pain Control Discovery
September 1, 2006 — A newly discovered enzyme inhibitor, identified by researchers originally looking for biological pest controls, may lead to pain relief for sufferers of arthritis and other inflammatory diseases, say ... > full story -
Study Finds That Vioxx Reduces The Risk Of Colorectal Polyps
August 31, 2006 — A researcher from Dartmouth reports the results of a clinical trial that shows that the cyclooxygenase-2 inhibitor rofecoxib reduces the risk of colorectal adenomas, or ... > full story -
New Study Re-evaluates Cardiovascular Risks Of Anti-inflammatory Drugs
June 2, 2006 — High doses of some traditional non-steroidal anti-inflammatory drugs (NSAIDS) are associated with similar cardiovascular risks as the new generation of anti-inflammatory drugs known as COX 2 ... > full story
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