Featured Research

from universities, journals, and other organizations

Low birth weight linked to higher incidence of type 2 diabetes in African American women

Date:
August 22, 2014
Source:
Boston University Medical Center
Summary:
African American women born at a low or very low birth weight may be at a higher risk for developing type 2 diabetes. The findings may explain in part the higher occurrence of type 2 diabetes in African American populations, which has a high prevalence of low birth weight.

African American women born at a low or very low birth weight may be at a higher risk for developing type 2 diabetes. The findings, which appear in Diabetes Care, may explain in part the higher occurrence of type 2 diabetes in African American populations, which has a high prevalence of low birth weight.

Related Articles


Researchers from Boston University's Slone Epidemiology Center followed more than 21,000 women enrolled in the Black Women's Health Study over the course of 16 years, analyzing characteristics such as birth weight, current age, family history of diabetes, body mass index, physical activity and socioeconomic status.

The study results indicate that women with low birth weight had a 13 percent higher chance of developing type 2 diabetes than those with normal birth weight, and those with very low birth weight had a 40 percent higher chance of developing the disease. Low birth weight was defined as less than 2.5 kg, and very low birth weight as less than 1.5 kg. It appeared that body size did not play a role in this relationship as there was a clear association between birth weight and diabetes even for women who were not obese.

Although previous studies have shown that birth characteristics such as birth weight can have a major impact on adult health, this is the first large-scale study to demonstrate this effect in an African American population.

"African American women are at increased risk of developing type 2 diabetes, and also have higher rates of low birth weight than white women," said Edward Ruiz-Narvαez, ScD, assistant professor of epidemiology at Boston University School of Public Health. "Our study shows a clear relationship between birth weight and diabetes that highlights the importance of further research for this at-risk group."

According to the researchers, there are two leading hypotheses for the phenomenon. The first, known as the "thrifty phenotype hypothesis," states that once the newborn body perceives that it lacks nutrition, it reprograms itself to absorb more nutrition, causing an imbalance in metabolism that eventually leads to type 2 diabetes. The second, known as the "fetal insulin hypothesis," states that genes that are responsible for impaired insulin secretion also have a negative effect on birth weight. Some of these genes have been discovered in recent studies, supporting the latter hypothesis.


Story Source:

The above story is based on materials provided by Boston University Medical Center. Note: Materials may be edited for content and length.


Journal Reference:

  1. E. A. Ruiz-Narvaez, J. R. Palmer, H. Gerlovin, L. A. Wise, V. G. Vimalananda, J. L. Rosenzweig, L. Rosenberg. Birth Weight and Risk of Type 2 Diabetes in the Black Women's Health Study: Does Adult BMI Play a Mediating Role? Diabetes Care, 2014; 37 (9): 2572 DOI: 10.2337/dc14-0731

Cite This Page:

Boston University Medical Center. "Low birth weight linked to higher incidence of type 2 diabetes in African American women." ScienceDaily. ScienceDaily, 22 August 2014. <www.sciencedaily.com/releases/2014/08/140822084051.htm>.
Boston University Medical Center. (2014, August 22). Low birth weight linked to higher incidence of type 2 diabetes in African American women. ScienceDaily. Retrieved December 21, 2014 from www.sciencedaily.com/releases/2014/08/140822084051.htm
Boston University Medical Center. "Low birth weight linked to higher incidence of type 2 diabetes in African American women." ScienceDaily. www.sciencedaily.com/releases/2014/08/140822084051.htm (accessed December 21, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Sunday, December 21, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Touch-Free Smart Phone Empowers Mobility-Impaired

Touch-Free Smart Phone Empowers Mobility-Impaired

Reuters - Innovations Video Online (Dec. 21, 2014) — A touch-free phone developed in Israel enables the mobility-impaired to operate smart phones with just a movement of the head. Suzannah Butcher reports. Video provided by Reuters
Powered by NewsLook.com
Earthworms Provide Cancer-Fighting Bacteria

Earthworms Provide Cancer-Fighting Bacteria

Reuters - Innovations Video Online (Dec. 21, 2014) — Polish scientists isolate bacteria from earthworm intestines which they say may be used in antibiotics and cancer treatments. Suzannah Butcher reports. Video provided by Reuters
Powered by NewsLook.com
Existing Chemical Compounds Could Revive Failing Antibiotics, Says Danish Scientist

Existing Chemical Compounds Could Revive Failing Antibiotics, Says Danish Scientist

Reuters - Innovations Video Online (Dec. 21, 2014) — A team of scientists led by Danish chemist Jorn Christensen says they have isolated two chemical compounds within an existing antipsychotic medication that could be used to help a range of failing antibiotics work against killer bacterial infections, such as Tuberculosis. Jim Drury went to meet him. Video provided by Reuters
Powered by NewsLook.com
Hugging It Out Could Help You Ward Off A Cold

Hugging It Out Could Help You Ward Off A Cold

Newsy (Dec. 21, 2014) — Carnegie Mellon researchers found frequent hugs can help people avoid stress-related illnesses. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins