Featured Research

from universities, journals, and other organizations

Salt Is Not The Only Factor -- Races Respond Differently To High Blood Pressure Treatment

Date:
June 2, 1997
Source:
University of Maryland at Baltimore
Summary:
Significant racial differences in response to high blood pressure medications persist even when the variable of salt sensitivity is controlled, says a University of Maryland School of Medicine researcher.

Significant racial differences in response to high blood pressuremedications persist even when the variable of salt sensitivity iscontrolled, says a University of Maryland School of Medicineresearcher. Up to now, the difference in salt sensitivity among raceswas believed to be the only factor influencing the effectiveness ofdifferent medications in lowering blood pressure in African Americans,Hispanic Americans and Caucasians.

At the American Society of Hypertension scientific meeting in SanFrancisco May 27-31, 1997, Dr. Matthew R. Weir presented findingsfrom a clinical trial involving two of the most common kinds of bloodpressure medication. A professor of medicine and head of the Divisionof Nephrology at the University of Maryland School of Medicine inBaltimore, Weir authored the multi-center study, which compared theblood pressure-lowering effects of enalapril, an angiotensinconverting enzyme (ACE) inhibitor, and the calcium channel antagonistisradipine during high and low salt intake.

Nearly 400 African Americans, Hispanic Americans and Caucasians withhigh blood pressure who also were known to be salt-sensitive werestudied. Weir and colleagues found that isradipine lowered bloodpressure more effectively in African Americans on a high salt diet,while both drugs worked equally well for African Americans on a lowsalt diet. In Caucasians, both medications produced similar bloodpressure reduction on a high salt diet, but enalapril was moreeffective for Caucasians who restricted their salt intake. InHispanic-Americans, both drugs lowered blood pressure to similarlevels on both high and low salt diets.

"Our results show that there are issues other than salt sensitivity inthe racial differences we see in response to antihypertensivemedications," Weir said. "We controlled for salt sensitivity, andracial differences - although lessened - persisted. This reinforcesthe importance of dietary salt restriction for people of all races whohave high blood pressure."

In another presentation at the hypertension meeting, Weir discussed the relationship of high blood pressure to kidney disease. "We arenow observing that more aggressive treatment of hypertension can beboth safe and effective in preventing kidney damage," he said.

END


Story Source:

The above story is based on materials provided by University of Maryland at Baltimore. Note: Materials may be edited for content and length.


Cite This Page:

University of Maryland at Baltimore. "Salt Is Not The Only Factor -- Races Respond Differently To High Blood Pressure Treatment." ScienceDaily. ScienceDaily, 2 June 1997. <www.sciencedaily.com/releases/1997/06/970602184617.htm>.
University of Maryland at Baltimore. (1997, June 2). Salt Is Not The Only Factor -- Races Respond Differently To High Blood Pressure Treatment. ScienceDaily. Retrieved August 21, 2014 from www.sciencedaily.com/releases/1997/06/970602184617.htm
University of Maryland at Baltimore. "Salt Is Not The Only Factor -- Races Respond Differently To High Blood Pressure Treatment." ScienceDaily. www.sciencedaily.com/releases/1997/06/970602184617.htm (accessed August 21, 2014).

Share This




More Health & Medicine News

Thursday, August 21, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Cadavers, a Teen, and a Medical School Dream

Cadavers, a Teen, and a Medical School Dream

AP (Aug. 21, 2014) — Contains graphic content. He's only 17. But Johntrell Bowles has wanted to be a doctor from a young age, despite the odds against him. He was recently the youngest participant in a cadaver program at the Indiana University NW medical school. (Aug. 21) Video provided by AP
Powered by NewsLook.com
Possible Ebola Patient in Isolation at California Hospital

Possible Ebola Patient in Isolation at California Hospital

Reuters - US Online Video (Aug. 20, 2014) — A patient who may have been exposed to the Ebola virus is in isolation at the Kaiser Permanente South Sacramento Medical Center. Linda So reports. Video provided by Reuters
Powered by NewsLook.com
Reasons Why Teen Birth Rates Are At An All-Time Low

Reasons Why Teen Birth Rates Are At An All-Time Low

Newsy (Aug. 20, 2014) — A CDC report says birth rates among teenagers have been declining for decades, reaching a new low in 2013. We look at several popular explanations. Video provided by Newsy
Powered by NewsLook.com
Common Antibiotic Could Lead To Heart-Related Death

Common Antibiotic Could Lead To Heart-Related Death

Newsy (Aug. 20, 2014) — Danish researchers discovered patients taking clarithromycin have an increased risk of dying from a heart-related issue. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins