Featured Research

from universities, journals, and other organizations

Salt Is Not The Only Factor -- Races Respond Differently To High Blood Pressure Treatment

Date:
June 2, 1997
Source:
University of Maryland at Baltimore
Summary:
Significant racial differences in response to high blood pressure medications persist even when the variable of salt sensitivity is controlled, says a University of Maryland School of Medicine researcher.

Significant racial differences in response to high blood pressure medications persist even when the variable of salt sensitivity is controlled, says a University of Maryland School of Medicine researcher. Up to now, the difference in salt sensitivity among races was believed to be the only factor influencing the effectiveness of different medications in lowering blood pressure in African Americans, Hispanic Americans and Caucasians.

At the American Society of Hypertension scientific meeting in San Francisco May 27-31, 1997, Dr. Matthew R. Weir presented findings from a clinical trial involving two of the most common kinds of blood pressure medication. A professor of medicine and head of the Division of Nephrology at the University of Maryland School of Medicine in Baltimore, Weir authored the multi-center study, which compared the blood pressure-lowering effects of enalapril, an angiotensin converting enzyme (ACE) inhibitor, and the calcium channel antagonist isradipine during high and low salt intake.

Nearly 400 African Americans, Hispanic Americans and Caucasians with high blood pressure who also were known to be salt-sensitive were studied. Weir and colleagues found that isradipine lowered blood pressure more effectively in African Americans on a high salt diet, while both drugs worked equally well for African Americans on a low salt diet. In Caucasians, both medications produced similar blood pressure reduction on a high salt diet, but enalapril was more effective for Caucasians who restricted their salt intake. In Hispanic-Americans, both drugs lowered blood pressure to similar levels on both high and low salt diets.

"Our results show that there are issues other than salt sensitivity in the racial differences we see in response to antihypertensive medications," Weir said. "We controlled for salt sensitivity, and racial differences - although lessened - persisted. This reinforces the importance of dietary salt restriction for people of all races who have high blood pressure."

In another presentation at the hypertension meeting, Weir discussed the relationship of high blood pressure to kidney disease. "We are now observing that more aggressive treatment of hypertension can be both safe and effective in preventing kidney damage," he said.

END


Story Source:

The above story is based on materials provided by University of Maryland at Baltimore. Note: Materials may be edited for content and length.


Cite This Page:

University of Maryland at Baltimore. "Salt Is Not The Only Factor -- Races Respond Differently To High Blood Pressure Treatment." ScienceDaily. ScienceDaily, 2 June 1997. <www.sciencedaily.com/releases/1997/06/970602184617.htm>.
University of Maryland at Baltimore. (1997, June 2). Salt Is Not The Only Factor -- Races Respond Differently To High Blood Pressure Treatment. ScienceDaily. Retrieved April 16, 2014 from www.sciencedaily.com/releases/1997/06/970602184617.htm
University of Maryland at Baltimore. "Salt Is Not The Only Factor -- Races Respond Differently To High Blood Pressure Treatment." ScienceDaily. www.sciencedaily.com/releases/1997/06/970602184617.htm (accessed April 16, 2014).

Share This



More Health & Medicine News

Wednesday, April 16, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Ebola Outbreak Now Linked To 121 Deaths

Ebola Outbreak Now Linked To 121 Deaths

Newsy (Apr. 15, 2014) The ebola virus outbreak in West Africa is now linked to 121 deaths. Health officials fear the virus will continue to spread in urban areas. Video provided by Newsy
Powered by NewsLook.com
Cognitive Function: Is It All Downhill From Age 24?

Cognitive Function: Is It All Downhill From Age 24?

Newsy (Apr. 15, 2014) A new study out of Canada says cognitive motor performance begins deteriorating around age 24. Video provided by Newsy
Powered by NewsLook.com
How Mt. Everest Helped Scientists Research Diabetes

How Mt. Everest Helped Scientists Research Diabetes

Newsy (Apr. 15, 2014) British researchers were able to use Mount Everest's low altitudes to study insulin resistance. They hope to find ways to treat diabetes. Video provided by Newsy
Powered by NewsLook.com
Carpenter's Injury Leads To Hundreds Of 3-D-Printed Hands

Carpenter's Injury Leads To Hundreds Of 3-D-Printed Hands

Newsy (Apr. 14, 2014) Richard van As lost all fingers on his right hand in a woodworking accident. Now, he's used the incident to create a prosthetic to help hundreds. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins