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Inhibiting Cell-Death Gene May Slow ALS Progression

Date:
July 2, 1997
Source:
Massachusetts General Hospital
Summary:
Researchers from the Massachusetts General Hospital have found that a cell-death gene may play a role in amyotrophic lateral sclerosis (ALS or Lou Gehrig's disease). In the July 3Nature, they report that inhibiting the ICE cell-death gene slowed the progression of an ALS-like illness in mice.

A team of researchers from the Massachusetts General Hospital (MGH) has found evidence that a key programmed cell death gene may play a role in amyotrophic lateral sclerosis (ALS or Lou Gehrig's disease). In the July 3 issue of Nature, the team reports that inhibiting the activity of the gene coding for a protein called ICE -- the first identified mammalian cell-death gene -- slowed the progression of symptoms in mice with a gene mutation causing an ALS-like illness.


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The above story is based on materials provided by Massachusetts General Hospital. Note: Materials may be edited for content and length.


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Massachusetts General Hospital. "Inhibiting Cell-Death Gene May Slow ALS Progression." ScienceDaily. ScienceDaily, 2 July 1997. <www.sciencedaily.com/releases/1997/07/970702155045.htm>.
Massachusetts General Hospital. (1997, July 2). Inhibiting Cell-Death Gene May Slow ALS Progression. ScienceDaily. Retrieved April 25, 2014 from www.sciencedaily.com/releases/1997/07/970702155045.htm
Massachusetts General Hospital. "Inhibiting Cell-Death Gene May Slow ALS Progression." ScienceDaily. www.sciencedaily.com/releases/1997/07/970702155045.htm (accessed April 25, 2014).

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