Featured Research

from universities, journals, and other organizations

Drug-Resistant Infection Once Found Only In Hospitals Now Present In Community

Date:
February 27, 1998
Source:
University Of Chicago Medical Center
Summary:
Drug-resistant Staphylococcus aureus, a predominantly hospital-acquired infection, has been identified in children outside of the hospital setting with no identified risk factors, according to a study by researchers at the University of Chicago Children's Hospital.

Drug-resistant Staphylococcus aureus, a predominantly hospital-acquired infection, has been identified in children outside of the hospital setting with no identified risk factors, according to a study by researchers at the University of Chicago Children's Hospital, published in the February 25 issue of the Journal of the American Medical Association.

Related Articles


"This is the first published study to indicate that methicillin-resistant Staphylococcus aureus (MRSA) infections that are already resistant to many types of antibiotics are now found in non-chronically ill children outside of the hospital environment," said Robert S. Daum, M.D., professor of pediatrics at the University of Chicago and a co-author of the study. "This suggests a significant change in the way the organism is spread among the population. We need additional research focused on the mechanisms of community-acquired infections."

The retrospective study looked at the medical records of children hospitalized for MRSA at the University of Chicago Children's Hospital. It compared the cases of children with MRSA from August 1988 to July 1990 with those seen from August 1993 to July 1995.

After examining the records of children with community-acquired MRSA during the two time periods, the researchers focused on children with no known risk factors for infection. Among eight children with "community-acquired" MRSA, only one case in the first two-year period lacked an identified risk factor, whereas 25 out of 35 cases in the second two-year period lacked an identified risk factor.

Risk factors for infection were described as previous hospitalization or frequent antibiotic use, history of intubation, an underlying chronic disorder, presence of a catheter, history of any surgical procedure, or household contact with a person who has identified risk factors.

The researchers also found interesting differences between hospital-acquired and community-acquired MRSA infections. Although hospital-acquired MRSA infections appeared to be drug resistant to many antibiotics, community-acquired MRSA infections were susceptible to drugs other than methicillin. However, the researchers predict this may change over time.

"This study should make physicians aware that community-acquired MRSA infections exist, but it should not change their current practice for treating the infection," said Betsy C. Herold, M.D., assistant professor of pediatrics at the University of Chicago and lead author of the study. "First-line antibiotics are still the best therapy for these infections."

The University of Chicago researchers conclude that the results of this study underscore the need for further investigation. They have already begun a study to evaluate the transmission of these organisms by identifying children colonized with Staphylococcus aureus that do not have symptoms of illness.

Dr. Herold's co-authors include Lilly C. Immergluck, M.D., Melinda C. Maranan, M.D., Diane S. Lauderdale, Ph.D., Ryan E. Gaskin, Susan Boyle-Vavra, Ph.D., Cindy D. Leitch, and senior author Robert S. Daum, M.D.

The University of Chicago Children's Hospital (UCCH) is a 156-bed acute care hospital at the University of Chicago Hospitals. As a major tertiary referral center, UCCH sees children with the most complex medical problems and annually admits more than 4,000 patients from the Chicago area, the Midwest and around the world.


Story Source:

The above story is based on materials provided by University Of Chicago Medical Center. Note: Materials may be edited for content and length.


Cite This Page:

University Of Chicago Medical Center. "Drug-Resistant Infection Once Found Only In Hospitals Now Present In Community." ScienceDaily. ScienceDaily, 27 February 1998. <www.sciencedaily.com/releases/1998/02/980227054708.htm>.
University Of Chicago Medical Center. (1998, February 27). Drug-Resistant Infection Once Found Only In Hospitals Now Present In Community. ScienceDaily. Retrieved November 1, 2014 from www.sciencedaily.com/releases/1998/02/980227054708.htm
University Of Chicago Medical Center. "Drug-Resistant Infection Once Found Only In Hospitals Now Present In Community." ScienceDaily. www.sciencedaily.com/releases/1998/02/980227054708.htm (accessed November 1, 2014).

Share This



More Health & Medicine News

Saturday, November 1, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Melafind: Spotting Melanoma Without a Biopsy

Melafind: Spotting Melanoma Without a Biopsy

Ivanhoe (Oct. 31, 2014) The MelaFind device is a pain-free way to check suspicious moles for melanoma, without the need for a biopsy. Video provided by Ivanhoe
Powered by NewsLook.com
Battling Multiple Myeloma

Battling Multiple Myeloma

Ivanhoe (Oct. 31, 2014) The answer isn’t always found in new drugs – repurposing an ‘old’ drug that could mean better multiple myeloma treatment, and hope. Video provided by Ivanhoe
Powered by NewsLook.com
Chronic Inflammation and Prostate Cancer

Chronic Inflammation and Prostate Cancer

Ivanhoe (Oct. 31, 2014) New information that is linking chronic inflammation in the prostate and prostate cancer, which may help doctors and patients prevent cancer in the future. Video provided by Ivanhoe
Powered by NewsLook.com
Sickle Cell: Stopping Kids’ Silent Strokes

Sickle Cell: Stopping Kids’ Silent Strokes

Ivanhoe (Oct. 31, 2014) Blood transfusions are proving crucial to young sickle cell patients by helping prevent strokes, even when there is no outward sign of brain injury. Video provided by Ivanhoe
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins