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Simplified Therapy To Prevent TB Proven Effective In Developing Countries

Date:
March 19, 1998
Source:
Johns Hopkins School Of Public Health
Summary:
People with HIV in developing countries are far more likely to contract tuberculosis than those without HIV. Now researchers at the Johns Hopkins School of Public have found that a simplified regimen of twice-weekly doses of isoniazid preventive therapy administered for six months or rifampicin and pyrazinamide administered for only two months provided similar overall protection against tuberculosis in HIV-infected, PPD-positive adults.

People with HIV in developing countries are far more likely to contract tuberculosis than those without HIV. Although drugs to help prevent TB are available, the normal course of treatment is 12 months, making it difficult for people to comply with treatment especially in countries where access to care is a problem as is monitoring medication. In most developing countries preventive therapy for high risk individuals is not given because of limited resources. Researchers at the Johns Hopkins School of Public have found that a simplified regimen of twice-weekly doses of isoniazid preventive therapy administered for six months or rifampicin and pyrazinamide administered for only two months provided similar overall protection against tuberculosis in HIV-infected, PPD-positive adults.


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The above story is based on materials provided by Johns Hopkins School Of Public Health. Note: Materials may be edited for content and length.


Cite This Page:

Johns Hopkins School Of Public Health. "Simplified Therapy To Prevent TB Proven Effective In Developing Countries." ScienceDaily. ScienceDaily, 19 March 1998. <www.sciencedaily.com/releases/1998/03/980319072638.htm>.
Johns Hopkins School Of Public Health. (1998, March 19). Simplified Therapy To Prevent TB Proven Effective In Developing Countries. ScienceDaily. Retrieved April 23, 2014 from www.sciencedaily.com/releases/1998/03/980319072638.htm
Johns Hopkins School Of Public Health. "Simplified Therapy To Prevent TB Proven Effective In Developing Countries." ScienceDaily. www.sciencedaily.com/releases/1998/03/980319072638.htm (accessed April 23, 2014).

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