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Research Uncovers A Key To Aging And Lifespan Determination

Date:
June 2, 1998
Source:
University Of Toronto
Summary:
A research team has identified a critical weakness in the defence against aging after increasing the life expectancy of fruit flies by 40 per cent by injecting them with a human gene known to be a key factor affecting aging and lifespan.

TORONTO -- A research team led by Dr. Gabrielle Boulianne of The Hospital for Sick Children (HSC) and the University of Toronto (U of T) and Drs. John Phillips and Arthur Hilliker of the University of Guelph has identified a critical weakness in the defence against aging. Using the fruit fly as a model biological system, the researchers discovered that a specific cell type -- the motor neuron -- is the major target for oxidative damage, known for several years to be a key factor affecting aging and lifespan. The researchers were able to boost the flies' defences by inserting a human gene which is known to protect against oxidative damage. As a result, the average lifespan of the flies (usually about 80 days) was increased by 40 percent. Their research is reported in the June issue of the scientific journal Nature Genetics.


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University Of Toronto. "Research Uncovers A Key To Aging And Lifespan Determination." ScienceDaily. ScienceDaily, 2 June 1998. <www.sciencedaily.com/releases/1998/06/980602075755.htm>.
University Of Toronto. (1998, June 2). Research Uncovers A Key To Aging And Lifespan Determination. ScienceDaily. Retrieved April 20, 2014 from www.sciencedaily.com/releases/1998/06/980602075755.htm
University Of Toronto. "Research Uncovers A Key To Aging And Lifespan Determination." ScienceDaily. www.sciencedaily.com/releases/1998/06/980602075755.htm (accessed April 20, 2014).

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