Featured Research

from universities, journals, and other organizations

Testosterone Improves Quality Of Life In Men With AIDS Wasting Syndrome

Date:
July 8, 1998
Source:
Massachusetts General Hospital
Summary:
A research team based at the Massachusetts General Hospital (MGH) has found that testosterone administration significantly increases lean body mass and improves the quality of life in men with AIDS wasting syndrome.

A research team based at the Massachusetts General Hospital (MGH) has found that testosterone administration significantly increases lean body mass and improves the quality of life in men with AIDS wasting syndrome. The AIDS wasting syndrome is a devastating complication of late-stage HIV infection, characterized by an extreme loss of lean muscle mass, leading to significant fatigue and frailty. The report appears in the July 1 issue of Annals of Internal Medicine.

Related Articles


"This is an important new therapy for patients with AIDS wasting syndrome. Physicians now will have a important tool to help build critically needed muscle mass and improve overall well being in men with AIDS wasting syndrome," said Steven Grinspoon, MD, of the MGH Neuroendocrine Unit, who led the study.

Fifty-one HIV-positive men aged 34 to 50 partipated in the study; they were selected because they had significant weight loss and low testosterone levels. Participants were randomly assigned to receive injections of either testosterone or a placebo every three weeks for six months. Injections were designed to produce normal testostone levels in those receiving the hormone.

Compared with the placebo group, those who received testosterone had signficant term benefit," he explains. "We believe all male patients with AIDS wasting syndrome should be screened for hormone deficiency and given testosterone if their levels are low, unless there is a medical reason not to do so."

The research was supported by grants from the National Institutes of Health. Grinspoon's co-authors include Anne Klibanski, MD, director of the MGH Neuroendocrine Unit and Colleen Corcoran, ANP, also of the MGH Neuro-endocrine Unit; David Schoenfeld, PhD; Douglas Hayden, MA; Ellen Anderson, MS, RD; Kristen Parlman, MSPT; and Nesli Basgoz, MD, also of the MGH; Hasan Askari, MBBS, of Washington University of St. Louis; Lisa Wolf, RN, of the Joslin Diabetes Center; Belton Burrows, MD, and Mark Walsh, MS, of the Boston VA Medical Center.


Story Source:

The above story is based on materials provided by Massachusetts General Hospital. Note: Materials may be edited for content and length.


Cite This Page:

Massachusetts General Hospital. "Testosterone Improves Quality Of Life In Men With AIDS Wasting Syndrome." ScienceDaily. ScienceDaily, 8 July 1998. <www.sciencedaily.com/releases/1998/07/980708085254.htm>.
Massachusetts General Hospital. (1998, July 8). Testosterone Improves Quality Of Life In Men With AIDS Wasting Syndrome. ScienceDaily. Retrieved December 18, 2014 from www.sciencedaily.com/releases/1998/07/980708085254.htm
Massachusetts General Hospital. "Testosterone Improves Quality Of Life In Men With AIDS Wasting Syndrome." ScienceDaily. www.sciencedaily.com/releases/1998/07/980708085254.htm (accessed December 18, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Thursday, December 18, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Kids Die While Under Protective Services

Kids Die While Under Protective Services

AP (Dec. 18, 2014) As part of a six-month investigation of child maltreatment deaths, the AP found that hundreds of deaths from horrific abuse and neglect could have been prevented. AP's Haven Daley reports. (Dec. 18) Video provided by AP
Powered by NewsLook.com
Dads-To-Be Also Experience Hormone Changes During Pregnancy

Dads-To-Be Also Experience Hormone Changes During Pregnancy

Newsy (Dec. 18, 2014) A study from University of Michigan researchers found that expectant fathers see a decrease in testosterone as the baby's birth draws near. Video provided by Newsy
Powered by NewsLook.com
Prenatal Exposure To Pollution Might Increase Autism Risk

Prenatal Exposure To Pollution Might Increase Autism Risk

Newsy (Dec. 18, 2014) Harvard researchers found children whose mothers were exposed to high pollution levels in the third trimester were twice as likely to develop autism. Video provided by Newsy
Powered by NewsLook.com
UN: Up to One Million Facing Hunger in Ebola-Hit Countries

UN: Up to One Million Facing Hunger in Ebola-Hit Countries

AFP (Dec. 17, 2014) Border closures, quarantines and crop losses in West African nations battling the Ebola virus could lead to as many as one million people going hungry, UN food agencies said on Wednesday. Duration: 00:52 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins