Featured Research

from universities, journals, and other organizations

Bacteria From Gum Infections Associated With Diabetes, Chronic Lung Disease, UB Studies Find

Date:
March 15, 1999
Source:
University At Buffalo
Summary:
Diabetes and chronic lung disease can be added to the growing list of systemic diseases and conditions associated with bacteria from infected gums, new studies from the University at Buffalo School of Dental Medicine have shown.

VANCOUVER, British Columbia -- Diabetes and chronic lung disease can be added to the growing list of systemic diseases and conditions associated with bacteria from infected gums, new studies from the University at Buffalo School of Dental Medicine have shown.

Related Articles


The findings from both studies were presented here today (March 13) at the combined meeting of the American Association of Dental Research and International Association of Dental Research.

To investigate the association of periodontal disease with diabetes, a research team headed by Sara G. Grossi, D.D.S., UB senior research scientist, concentrated on insulin resistance, a known precursor of active diabetes, in which cells do not absorb insulin from the blood stream.

As their study group, the researchers used 11,198 subjects from the Third National Health and Nutrition Examination Survey (NHANES III) conducted from 1988-94, including all non-diabetic NHANES participants between the ages of 20 and 90 who had at least six natural teeth.

They assessed information on periodontal status, defined as degree of gum detachment from bone, along with fasting-insulin and fasting-glucose levels, which were combined to establish an index of insulin resistance. Persons with known diabetes or with a blood glucose level that reached diabetic levels were excluded from the analysis.

Analysis showed that the index of insulin resistance increased as severity of periodontal disease increased. The relationship was not affected by age, gender, body-mass index (a measure of obesity) or smoking. To clarify the relationship further, the researchers separated the study group into overweight versus non-overweight, using a body mass index of 27 as the dividing line. Weight is an independent risk factor for insulin resistance and diabetes.

Results showed that those with severe periodontal disease (gum detachment), regardless of weight, have a higher index of insulin resistance than those with little or no disease.

"Gram-negative periodontal infections are significantly associated with insulin resistance in non-diabetics," Grossi said. "We know that when diabetics have an acute infection, their diabetes goes out of control. Gram-negative bacteria produce a very potent toxin called LPS, which probably interferes with the action of insulin and is responsible for maintaining a chronic state of insulin resistance in people with gum infections," she said.

The study on the relationship between periodontal infection and chronic lung disease was designed to follow up earlier reports of a link between poor oral hygiene, gum disease and chronic lung disease, also using data from NHANES III.

Frank Scannapieco, D.M.D, Ph.D., assistant professor of oral biology, analyzed data from 13,792 adults concerning the incidence of pneumonia, asthma, bronchitis and/or emphysema and the condition of their oral health, using degree of gum detachment from bone as an indicator.

Results showed that persons with chronic lung conditions had more gum detachment than those with no lung disease, after correction for age, gender, race, ethnicity, education, income, frequency of dental visits, smoking and alcohol consumption.

There also was a direct correlation between the amount of detachment and lung-disease risk. Subjects with gum detachment that exceeded 2 mm had a 40 percent greater risk of developing lung disease than those with attachment loss of less than 2 mm, results showed.


Story Source:

The above story is based on materials provided by University At Buffalo. Note: Materials may be edited for content and length.


Cite This Page:

University At Buffalo. "Bacteria From Gum Infections Associated With Diabetes, Chronic Lung Disease, UB Studies Find." ScienceDaily. ScienceDaily, 15 March 1999. <www.sciencedaily.com/releases/1999/03/990315081825.htm>.
University At Buffalo. (1999, March 15). Bacteria From Gum Infections Associated With Diabetes, Chronic Lung Disease, UB Studies Find. ScienceDaily. Retrieved October 30, 2014 from www.sciencedaily.com/releases/1999/03/990315081825.htm
University At Buffalo. "Bacteria From Gum Infections Associated With Diabetes, Chronic Lung Disease, UB Studies Find." ScienceDaily. www.sciencedaily.com/releases/1999/03/990315081825.htm (accessed October 30, 2014).

Share This



More Health & Medicine News

Thursday, October 30, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Mind-Controlled Prosthetic Arm Restores Amputee Dexterity

Mind-Controlled Prosthetic Arm Restores Amputee Dexterity

Reuters - Innovations Video Online (Oct. 29, 2014) A Swedish amputee who became the first person to ever receive a brain controlled prosthetic arm is able to manipulate and handle delicate objects with an unprecedented level of dexterity. The device is connected directly to his bone, nerves and muscles, giving him the ability to control it with his thoughts. Matthew Stock reports. Video provided by Reuters
Powered by NewsLook.com
Google To Use Nanoparticles, Wearables To Detect Disease

Google To Use Nanoparticles, Wearables To Detect Disease

Newsy (Oct. 29, 2014) Google X wants to improve modern medicine with nanoparticles and a wearable device. It's all an attempt to tackle disease detection and prevention. Video provided by Newsy
Powered by NewsLook.com
Can Drinking Milk Lead To Early Death?

Can Drinking Milk Lead To Early Death?

Newsy (Oct. 29, 2014) Researchers in Sweden released a study showing heavy milk drinkers face an increased mortality risk from a variety of causes. Video provided by Newsy
Powered by NewsLook.com
Obama: The US Will Not 'run and Hide' From Ebola

Obama: The US Will Not 'run and Hide' From Ebola

AP (Oct. 29, 2014) Surrounded by health care workers in the White House East Room, President Barack Obama said the U.S. will likely see additional Ebola cases in the weeks ahead. But he said the nation can't seal itself off in the fight against the disease. (Oct. 29) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

    Environment News

    Technology News



    Save/Print:
    Share:

    Free Subscriptions


    Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

    Get Social & Mobile


    Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

    Have Feedback?


    Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
    Mobile: iPhone Android Web
    Follow: Facebook Twitter Google+
    Subscribe: RSS Feeds Email Newsletters
    Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins