Blood test results from hayfever victims testing an experimental anti-allergy drug have led investigators at the Johns Hopkins Asthma and Allergy Center to discovery of an essential immune system feedback loop that appears to be a basic mechanism driving all allergies. The biochemical loop, the scientists say, links the amount of immunoglobulin E (IgE) antibody, overabundant in people with allergies, to the number of immune cell IgE receptors, which, upon exposure to allergens, trigger a cascade of biological events that cause wheezing, sneezing, itching and swelling so common this time of year.
The above story is based on materials provided by Johns Hopkins Medical Institutions. Note: Materials may be edited for content and length.
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