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Essential "Allergy Feedback Loop" Discovered By Hopkins Scientists

Date:
May 6, 1999
Source:
Johns Hopkins Medical Institutions
Summary:
Blood test results from hayfever victims testing an experimental anti-allergy drug have led investigators at the Johns Hopkins Asthma and Allergy Center to discovery of an essential immune system feedback loop that appears to be a basic mechanism driving all allergies.

Blood test results from hayfever victims testing an experimental anti-allergy drug have led investigators at the Johns Hopkins Asthma and Allergy Center to discovery of an essential immune system feedback loop that appears to be a basic mechanism driving all allergies. The biochemical loop, the scientists say, links the amount of immunoglobulin E (IgE) antibody, overabundant in people with allergies, to the number of immune cell IgE receptors, which, upon exposure to allergens, trigger a cascade of biological events that cause wheezing, sneezing, itching and swelling so common this time of year.


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The above story is based on materials provided by Johns Hopkins Medical Institutions. Note: Materials may be edited for content and length.


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Johns Hopkins Medical Institutions. "Essential "Allergy Feedback Loop" Discovered By Hopkins Scientists." ScienceDaily. ScienceDaily, 6 May 1999. <www.sciencedaily.com/releases/1999/05/990505165340.htm>.
Johns Hopkins Medical Institutions. (1999, May 6). Essential "Allergy Feedback Loop" Discovered By Hopkins Scientists. ScienceDaily. Retrieved April 17, 2014 from www.sciencedaily.com/releases/1999/05/990505165340.htm
Johns Hopkins Medical Institutions. "Essential "Allergy Feedback Loop" Discovered By Hopkins Scientists." ScienceDaily. www.sciencedaily.com/releases/1999/05/990505165340.htm (accessed April 17, 2014).

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