Featured Research

from universities, journals, and other organizations

Phytochemicals In Apples Are Found To Provide Anticancer And Anti-Oxidant Benefits, Cornell Researchers Show

Date:
June 27, 2000
Source:
Cornell University
Summary:
Time to adjust an old adage: It's the phytochemicals in the apple each day that keep the doctor away. A combination of plant chemicals, such as flavanoids and polyphenols -- collectively known as phytochemicals -- found both within the flesh of apple and particularly in the skin -- provide the fruit's anti-oxidant and anti-cancer benefits, say Cornell food scientists.

ITHACA, N.Y. -- Time to adjust an old adage: It's the phytochemicals in the apple each day that keep the doctor away.

A combination of plant chemicals, such as flavanoids and polyphenols -- collectively known as phytochemicals -- found both within the flesh of apple and particularly in the skin -- provide the fruit's anti-oxidant and anti-cancer benefits, say Cornell food scientists.

Their laboratory study, funded by the New York Apple Research Development Program and New York Apple Association, is published in the June 22 issue of the journal Nature.

Although it has long been known that apples provide anti-oxidant and health benefits, "this concept is different," says Rui Hai Liu, Cornell assistant professor of food science and lead author on the Nature article, "Anti-oxidant activity of fresh apples."

Says Liu: "Scientists are interested in isolating single compounds -- such as vitamin C, vitamin E and beta carotene -- to see if they exhibit anti-oxidant or anti-cancer benefits. It turns out that none of those works alone to reduce cancer. It's the combination of flavonoids and polyphenols doing the work."

An anti-oxidant is one of many chemicals that reduce or prevent oxidation, thus preventing cell and tissue damage from free radicals in the body.

"In this research, we have shown the importance of phytochemicals to human health," says Liu's collaborator, Chang Yong Lee, Cornell professor of food science at the university's New York State Agricultural Experiment Station in Geneva, N.Y. "Some of the phytochemicals are known to be anti-allergenic, some are anti-carcinogenic, anti-inflammatory, anti-viral, anti-proliferative. Now I have a reason to say an apple a day keeps the doctor away."

Marian V. Eberhardt, a graduate student in food chemistry who works in Liu's laboratory, also was part of the research team.

The researchers found that vitamin C in apples is only responsible for a small portion of the anti-oxidant activity. Instead, almost all of this activity in apples is from phytochemicals. Indeed, previous studies have shown that a 500 milligram vitamin C pill might act as a pro-oxidant. The Cornell researchers found that eating 100 grams of fresh apple with skins provided the total anti-oxidant activity equal to 1,500 milligrams of vitamin C.

"Eating fruits and vegetables is better than taking a vitamin pill," says Liu. "You can obtain enough anti-oxidants from food without worrying about toxicity. What this study shows is the combination of phytochemicals plays a very important role in anti-oxidant and anti-cancer activity, and the real health benefits may come from a phytochemical mixture."

The researchers used red delicious apples grown in New York state to provide the extracts to study the effects of phytochemicals. The researchers compared the anti-cancer and anti-oxidant activity in the apple flesh, and they also studied the fruit's skin.

Using colon cancer cells treated with apple extract, the scientists found that cell proliferation was inhibited. Colon cancer cells treated with 50 milligrams of apple extract (from the skins) were inhibited by 43 percent. The apple flesh extract inhibited the colon cancer cells by 29 percent.

The researchers also tested the apple extract against human liver cancer cells. At

50 milligrams, the extract derived from the apple with the skin on inhibited those cancer cells by 57 percent, and the apple extract derived from the fruit's fleshy part inhibited cancer cells by 40 percent.

"The consumption of whole fruits may provide the balanced anti-oxidants needed to quench reactive oxygen species," write the researchers in the Nature article. "Phytochemicals other than ascorbic acid (vitamin C) ... contribute significantly to the anti-oxidant activity of apples and to the capacity to inhibit tumor cell proliferation."

Lee began studying the enzymatic browning action of apples about 15 years ago, identifying a variety of phenolic compounds and learning how these chemicals work during the apple's browning action. Liu and Lee are working to study the antioxidant activity of various fruits and vegetables. The researchers learned that the amount of phenolic compounds in the apple flesh and in the skin varied from year to year, season to season and from growing region to growing region.


Story Source:

The above story is based on materials provided by Cornell University. Note: Materials may be edited for content and length.


Cite This Page:

Cornell University. "Phytochemicals In Apples Are Found To Provide Anticancer And Anti-Oxidant Benefits, Cornell Researchers Show." ScienceDaily. ScienceDaily, 27 June 2000. <www.sciencedaily.com/releases/2000/06/000625232319.htm>.
Cornell University. (2000, June 27). Phytochemicals In Apples Are Found To Provide Anticancer And Anti-Oxidant Benefits, Cornell Researchers Show. ScienceDaily. Retrieved September 16, 2014 from www.sciencedaily.com/releases/2000/06/000625232319.htm
Cornell University. "Phytochemicals In Apples Are Found To Provide Anticancer And Anti-Oxidant Benefits, Cornell Researchers Show." ScienceDaily. www.sciencedaily.com/releases/2000/06/000625232319.htm (accessed September 16, 2014).

Share This



More Health & Medicine News

Tuesday, September 16, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

President To Send 3,000 Military Personnel To Fight Ebola

President To Send 3,000 Military Personnel To Fight Ebola

Newsy (Sep. 16, 2014) President Obama is expected to send 3,000 troops to West Africa as part of the effort to contain Ebola's spread. Video provided by Newsy
Powered by NewsLook.com
Man Floats for 31 Hours in Gulf Waters

Man Floats for 31 Hours in Gulf Waters

AP (Sep. 16, 2014) A Texas man is lucky to be alive after he and three others floated for more than a day in the Gulf of Mexico when their boat sank during a fishing trip. (Sept. 16) Video provided by AP
Powered by NewsLook.com
Ivorians Abandon Monkey Pets in Fear Over Ebola Virus

Ivorians Abandon Monkey Pets in Fear Over Ebola Virus

AFP (Sep. 16, 2014) Since the arrival of Ebola in Ivory Coast, Ivorians have been abandoning their pets, particularly monkeys, in the fear that they may transmit the virus. Duration: 00:47 Video provided by AFP
Powered by NewsLook.com
Study Links Male-Pattern Baldness To Prostate Cancer

Study Links Male-Pattern Baldness To Prostate Cancer

Newsy (Sep. 16, 2014) New findings suggest men with a certain type of baldness at age 45 are 39 percent more likely to develop aggressive prostate cancer. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins