Featured Research

from universities, journals, and other organizations

Oral Biologists Demonstrate Gene Transfer Between Unrelated Oral Bacteria; Findings Indicate Possible Pathway For Development Of Antibiotic Resistance

Date:
March 21, 2001
Source:
University At Buffalo
Summary:
Oral bacteria can exchange genes, raising the possibility that organisms in the oral cavity can be transformed from harmless to destructive, and from antibiotic-susceptible to antibiotic-resistant, oral biologists at the University at Buffalo School of Dental Medicine have found.

CHICAGO -- Oral bacteria can exchange genes, raising the possibility that organisms in the oral cavity can be transformed from harmless to destructive, and from antibiotic-susceptible to antibiotic-resistant, oral biologists at the University at Buffalo School of Dental Medicine have found.

Related Articles


In findings presented here today (March 9, 2001) at the annual meeting of the American Association for Dental Research, UB dental researchers showed direct experimental evidence that horizontal gene transfer can occur between two different families of bacteria commonly found in the mouth.

"We carried out these experiments to examine the possibility that bacteria in dental plaque may exchange genetic information between each other," said Howard K. Kuramitsu, Ph.D., UB professor of oral biology and microbiology and senior author on the study.

"Our studies demonstrated genetic exchange between two markedly distinct oral bacteria -- an oral spirochete and a streptococcus. Therefore, exchange between two closely related bacteria, such as the one responsible for dental caries -- Streptococcus mutans -- and the harmless Streptococcus gordonii is highly probable."

Kuramitsu and Bingyan Wang, M.D., a post-doctoral researcher, used an erythromycin-resistant plasmid as a marker of gene transfer. A plasmid is an extra-chromosomal self-replicating structure found in bacteria cells that carries genes for a variety of functions not essential for cell growth, such as antibiotic resistance.

The researchers cultivated Streptococcus gordonii in the presence of the plasmid alone and separately with the bacteria Treponema denticola harboring the plasmid marker. After a period of cultivation, they detected genes from the marker plasmid within S. gordonii under both growth scenarios. Isolation of plasmids from the later strain could be followed by transformation into Escherichia coli.

"These findings could be important in the transfer of antibiotic resistance between plaque organisms, as well as with more harmful bacteria that temporarily colonize the oral cavity," Kuramitsu said. "In addition, this process could be important in understanding the evolution of plaque bacteria and could explain why some organisms exhibit certain virulent properties, such as the ability to colonize teeth."

The research was supported by grants from the National Institutes of Health.


Story Source:

The above story is based on materials provided by University At Buffalo. Note: Materials may be edited for content and length.


Cite This Page:

University At Buffalo. "Oral Biologists Demonstrate Gene Transfer Between Unrelated Oral Bacteria; Findings Indicate Possible Pathway For Development Of Antibiotic Resistance." ScienceDaily. ScienceDaily, 21 March 2001. <www.sciencedaily.com/releases/2001/03/010312072551.htm>.
University At Buffalo. (2001, March 21). Oral Biologists Demonstrate Gene Transfer Between Unrelated Oral Bacteria; Findings Indicate Possible Pathway For Development Of Antibiotic Resistance. ScienceDaily. Retrieved October 25, 2014 from www.sciencedaily.com/releases/2001/03/010312072551.htm
University At Buffalo. "Oral Biologists Demonstrate Gene Transfer Between Unrelated Oral Bacteria; Findings Indicate Possible Pathway For Development Of Antibiotic Resistance." ScienceDaily. www.sciencedaily.com/releases/2001/03/010312072551.htm (accessed October 25, 2014).

Share This



More Health & Medicine News

Saturday, October 25, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Texas Nurse Nina Pham Cured of Ebola

Texas Nurse Nina Pham Cured of Ebola

AFP (Oct. 25, 2014) — An American nurse who contracted Ebola while caring for a Liberian patient in Texas has been declared free of the virus and will leave the hospital. Duration: 01:01 Video provided by AFP
Powered by NewsLook.com
IKEA Desk Converts From Standing to Sitting With One Button

IKEA Desk Converts From Standing to Sitting With One Button

Buzz60 (Oct. 24, 2014) — IKEA is out with a new convertible desk that can convert from a sitting desk to a standing one with just the push of a button. Jen Markham explains. Video provided by Buzz60
Powered by NewsLook.com
Ebola Protective Suits Being Made in China

Ebola Protective Suits Being Made in China

AFP (Oct. 24, 2014) — A factory in China is busy making Ebola protective suits for healthcare workers and others fighting the spread of the virus. Duration: 00:38 Video provided by AFP
Powered by NewsLook.com
WHO: Millions of Ebola Vaccine Doses by 2015

WHO: Millions of Ebola Vaccine Doses by 2015

AP (Oct. 24, 2014) — The World Health Organization said on Friday that millions of doses of two experimental Ebola vaccines could be ready for use in 2015 and five more experimental vaccines would start being tested in March. (Oct. 24) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins