Featured Research

from universities, journals, and other organizations

Relapsed Smokers Can Be Successfully Re-Treated

Date:
March 29, 2001
Source:
Oregon Health Sciences University
Summary:
In one of the first "recycling" studies to examine people who attempt to quit smoking after first failing medical treatment, researchers at Oregon Health Sciences University and their colleagues found abstinence rates five times greater for participants taking bupropion compared to participants taking a placebo.

PORTLAND, Ore. – In one of the first "recycling" studies to examine people who attempt to quit smoking after first failing medical treatment, researchers at Oregon Health Sciences University and their colleagues found abstinence rates five times greater for participants taking bupropion compared to participants taking a placebo. Study results are being presented at 12 p.m. on Saturday, March 24, at the Society for Research on Nicotine and Tobacco Annual Meeting in Seattle.

"Patients often feel discouraged following treatment with medications such as bupropion or nicotine patches if they are unable to successfully quit smoking," said David Gonzales, Ph.D., director of the OHSU Smoking Cessation Center and lead author of the study results. "However, evidence-based options for patients in this situation have been few. This is the first study to show that smokers can be retreated with bupropion successfully."

Bupropion, marketed in sustained release form as Zyban, is a nicotine-free prescription medication designed to reduce nicotine cravings and other symptoms normally associated with nicotine withdrawal. The multicenter study involved 450 adult cigarette smokers who averaged 15 cigarettes per day prior to the study, and who had been unable to quit or had relapsed after a previous course of bupropion. Study participants were randomly selected to receive bupropion SR or a placebo.

Typically, people who attempt to quit smoking on their own experience 5 percent to 7 percent success rates, while smokers who try bupropion a first time generally enjoy a better-than-30 percent long-term success rate. In this study, smokers re-treated with the drug had a 27 percent abstinence rate after seven weeks, compared to 5 percent abstinence for the placebo group. At 12 weeks, 20 percent of smokers being re-treated were still smoke free compared to three percent of the subjects in the placebo group.

Zyban is marketed by GlaxoSmithKline Pharmaceuticals.


Story Source:

The above story is based on materials provided by Oregon Health Sciences University. Note: Materials may be edited for content and length.


Cite This Page:

Oregon Health Sciences University. "Relapsed Smokers Can Be Successfully Re-Treated." ScienceDaily. ScienceDaily, 29 March 2001. <www.sciencedaily.com/releases/2001/03/010327080439.htm>.
Oregon Health Sciences University. (2001, March 29). Relapsed Smokers Can Be Successfully Re-Treated. ScienceDaily. Retrieved October 21, 2014 from www.sciencedaily.com/releases/2001/03/010327080439.htm
Oregon Health Sciences University. "Relapsed Smokers Can Be Successfully Re-Treated." ScienceDaily. www.sciencedaily.com/releases/2001/03/010327080439.htm (accessed October 21, 2014).

Share This



More Mind & Brain News

Tuesday, October 21, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

First-Of-Its-Kind Treatment Gives Man Ability To Walk Again

First-Of-Its-Kind Treatment Gives Man Ability To Walk Again

Newsy (Oct. 21, 2014) A medical team has for the first time given a man the ability to walk again after transplanting cells from his brain onto his severed spinal cord. Video provided by Newsy
Powered by NewsLook.com
Portable Breathalyzer Gets You Home Safely

Portable Breathalyzer Gets You Home Safely

Buzz60 (Oct. 21, 2014) Breeze, a portable breathalyzer, gets you home safely by instantly showing your blood alcohol content, and with one tap, lets you call an Uber, a cab or a friend from your contact list to pick you up. Sean Dowling (@SeanDowlingTV) has the details. Video provided by Buzz60
Powered by NewsLook.com
Your Birth Season Might Determine Your Temperament

Your Birth Season Might Determine Your Temperament

Newsy (Oct. 20, 2014) A new study says the season you're born in can determine your temperament — and one season has a surprising outcome. Video provided by Newsy
Powered by NewsLook.com
Movies Might Desensitize Violence For Parents, Not Just Kids

Movies Might Desensitize Violence For Parents, Not Just Kids

Newsy (Oct. 20, 2014) A study suggests that parents become desensitized to violent movies as well as children, which leads them to allow their kids to view violent films. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins