Featured Research

from universities, journals, and other organizations

Relapsed Smokers Can Be Successfully Re-Treated

Date:
March 29, 2001
Source:
Oregon Health Sciences University
Summary:
In one of the first "recycling" studies to examine people who attempt to quit smoking after first failing medical treatment, researchers at Oregon Health Sciences University and their colleagues found abstinence rates five times greater for participants taking bupropion compared to participants taking a placebo.

PORTLAND, Ore. – In one of the first "recycling" studies to examine people who attempt to quit smoking after first failing medical treatment, researchers at Oregon Health Sciences University and their colleagues found abstinence rates five times greater for participants taking bupropion compared to participants taking a placebo. Study results are being presented at 12 p.m. on Saturday, March 24, at the Society for Research on Nicotine and Tobacco Annual Meeting in Seattle.

Related Articles


"Patients often feel discouraged following treatment with medications such as bupropion or nicotine patches if they are unable to successfully quit smoking," said David Gonzales, Ph.D., director of the OHSU Smoking Cessation Center and lead author of the study results. "However, evidence-based options for patients in this situation have been few. This is the first study to show that smokers can be retreated with bupropion successfully."

Bupropion, marketed in sustained release form as Zyban, is a nicotine-free prescription medication designed to reduce nicotine cravings and other symptoms normally associated with nicotine withdrawal. The multicenter study involved 450 adult cigarette smokers who averaged 15 cigarettes per day prior to the study, and who had been unable to quit or had relapsed after a previous course of bupropion. Study participants were randomly selected to receive bupropion SR or a placebo.

Typically, people who attempt to quit smoking on their own experience 5 percent to 7 percent success rates, while smokers who try bupropion a first time generally enjoy a better-than-30 percent long-term success rate. In this study, smokers re-treated with the drug had a 27 percent abstinence rate after seven weeks, compared to 5 percent abstinence for the placebo group. At 12 weeks, 20 percent of smokers being re-treated were still smoke free compared to three percent of the subjects in the placebo group.

Zyban is marketed by GlaxoSmithKline Pharmaceuticals.


Story Source:

The above story is based on materials provided by Oregon Health Sciences University. Note: Materials may be edited for content and length.


Cite This Page:

Oregon Health Sciences University. "Relapsed Smokers Can Be Successfully Re-Treated." ScienceDaily. ScienceDaily, 29 March 2001. <www.sciencedaily.com/releases/2001/03/010327080439.htm>.
Oregon Health Sciences University. (2001, March 29). Relapsed Smokers Can Be Successfully Re-Treated. ScienceDaily. Retrieved February 1, 2015 from www.sciencedaily.com/releases/2001/03/010327080439.htm
Oregon Health Sciences University. "Relapsed Smokers Can Be Successfully Re-Treated." ScienceDaily. www.sciencedaily.com/releases/2001/03/010327080439.htm (accessed February 1, 2015).

Share This


More From ScienceDaily



More Mind & Brain News

Sunday, February 1, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

NFL Concussions Down; Still on Parents' Minds

NFL Concussions Down; Still on Parents' Minds

AP (Jan. 30, 2015) The NFL announced this week that the number of game concussions dropped by a quarter over last season. Still, the dangers of the sport still weigh on players, and parents&apos; minds. (Jan. 30) Video provided by AP
Powered by NewsLook.com
Study Shows Newborn Chicks Count From Left to Right Just Like Humans

Study Shows Newborn Chicks Count From Left to Right Just Like Humans

Buzz60 (Jan. 30, 2015) Researchers for the first time identified human&apos;s innate preference for associating low and high numbers with the left and right respectively in another species. Jen Markham (@jenmarkham) explains. Video provided by Buzz60
Powered by NewsLook.com
Best Mood Elevating, Feel Good Shakes & Smoothies

Best Mood Elevating, Feel Good Shakes & Smoothies

Buzz60 (Jan. 30, 2015) You can elevate your mood by having a meal in a glass. Fitness and nutrition expert John Basedow (@JohnBasedow) offers the best &apos;feel good&apos; smoothies and shakes chock full of depression-relieving ingredients...including apples, berries, lemons, cucumbers, papaya, kiwi, spinach, kale, whey protein, matcha, ginger, turmeric and cinnamon. Video provided by Buzz60
Powered by NewsLook.com
Poll Says Firstborn Is Responsible, Youngest Is Funnier

Poll Says Firstborn Is Responsible, Youngest Is Funnier

Newsy (Jan. 30, 2015) According to a poll out of the U.K., eldest siblings feel more responsible and successful than their younger siblings. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins