Featured Research

from universities, journals, and other organizations

New Radiation Technique Benefits Patients With Nasal-Passage Cancer

Date:
May 17, 2001
Source:
Washington University School Of Medicine
Summary:
Patients with advanced cancer of the nasal passages who receive a combination of chemotherapy and a cutting-edge radiation technique called intensity modulated radiation therapy (IMRT) live longer than patients who receive conventional radiation, according to a preliminary study at Washington University School of Medicine in St. Louis.

St. Louis, May 14, 2001 — Patients with advanced cancer of the nasal passages who receive a combination of chemotherapy and a cutting-edge radiation technique called intensity modulated radiation therapy (IMRT) live longer than patients who receive conventional radiation, according to a preliminary study at Washington University School of Medicine in St. Louis.

Related Articles


"We found that cancer patients who were treated here with chemotherapy and IMRT were better off than the national standard," said K.S. Clifford Chao, M.D., assistant professor of radiology.

Chao and his colleagues present their results May 14 at the annual meeting of the American Society of Clinical Oncology in San Francisco.

The researchers studied 125 patients with tumors of the nasopharynx, or nasal passages. The patients were treated at Washington University’s Mallinckrodt Institute of Radiology between 1971 and 1999. One hundred and three received conventional radiation therapy alone. Twenty-two patients received radiation with chemotherapy. Of the latter, 13 received conventional radiation and nine were treated with the newer IMRT technique.

Chao and colleagues compared their results with findings from several medical centers nationwide that participated in research called the Intergroup Study. The larger study compared conventional radiation with radiation plus chemotherapy. It did not include any patients receiving IMRT. Three-year cancer-free survival for radiation therapy alone was 51 percent for MIR patients compared with 24 percent in the nationwide study. For those who received chemotherapy with radiation, the survival rate was 90 percent for MIR patients and 69 percent for patients nationally. For the 9 patients who received IMRT and chemotherapy, the rate was 100 percent.

As an emerging technique, IMRT precisely targets tumor cells while sparing surrounding normal tissue. This means nerves to the eyes and brain are less likely to receive unintended radiation during treatment of nasopharyngeal cancer.

"In general, the tumor gets a higher concentration of radiation with IMRT," said Chao, who also is a staff physician at Barnes-Jewish Hospital.

Chao previously showed that IMRT minimizes damage to salivary glands, sparing patients the long-term discomfort of dry mouth. Patients receiving conventional radiation for head and neck cancers often suffer from this side effect, which causes constant thirst and inability to speak or eat normally. The new study concurs with these findings. One year after radiation treatment, patients who had received IMRT had dryness of the mouth significantly less often than did patients who had received conventional radiation therapy.

Chao CK, Cegniz M, Perez CA, Arquette M. Superior functional outcome with IMRT in locally advanced nasopharyngeal carcinoma. Poster presentation at American Society for Clinical Oncology annual meeting, San Francisco, May 12-15, 2001.

Funding from the National Cancer Institute supported this research.

The full-time and volunteer faculty of Washington University School of Medicine are the physicians and surgeons of Barnes-Jewish and St. Louis Children's hospitals. The School of Medicine is one of the leading medical research, teaching and patient-care institutions in the nation. Through its affiliations with Barnes-Jewish and St. Louis Children's hospitals, the School of Medicine is linked to BJC HealthCare.


Story Source:

The above story is based on materials provided by Washington University School Of Medicine. Note: Materials may be edited for content and length.


Cite This Page:

Washington University School Of Medicine. "New Radiation Technique Benefits Patients With Nasal-Passage Cancer." ScienceDaily. ScienceDaily, 17 May 2001. <www.sciencedaily.com/releases/2001/05/010515075923.htm>.
Washington University School Of Medicine. (2001, May 17). New Radiation Technique Benefits Patients With Nasal-Passage Cancer. ScienceDaily. Retrieved November 26, 2014 from www.sciencedaily.com/releases/2001/05/010515075923.htm
Washington University School Of Medicine. "New Radiation Technique Benefits Patients With Nasal-Passage Cancer." ScienceDaily. www.sciencedaily.com/releases/2001/05/010515075923.htm (accessed November 26, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Wednesday, November 26, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

From Popcorn To Vending Snacks: FDA Ups Calorie Count Rules

From Popcorn To Vending Snacks: FDA Ups Calorie Count Rules

Newsy (Nov. 25, 2014) — The US FDA is announcing new calorie rules on Tuesday that will require everywhere from theaters to vending machines to include calorie counts. Video provided by Newsy
Powered by NewsLook.com
Daily Serving Of Yogurt Could Reduce Risk Of Type 2 Diabetes

Daily Serving Of Yogurt Could Reduce Risk Of Type 2 Diabetes

Newsy (Nov. 25, 2014) — Need another reason to eat yogurt every day? Researchers now say it could reduce a person's risk of developing type 2 diabetes. Video provided by Newsy
Powered by NewsLook.com
Madagascar Working to Contain Plague Outbreak

Madagascar Working to Contain Plague Outbreak

AFP (Nov. 24, 2014) — Madagascar said Monday it is trying to contain an outbreak of plague -- similar to the Black Death that swept Medieval Europe -- that has killed 40 people and is spreading to the capital Antananarivo. Duration: 00:42 Video provided by AFP
Powered by NewsLook.com
Are Female Bosses More Likely To Be Depressed?

Are Female Bosses More Likely To Be Depressed?

Newsy (Nov. 24, 2014) — A new study links greater authority with increased depressive symptoms among women in the workplace. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins