PHILADELPHIA - In a new study, when a strain of mice prone to atherosclerosis - cardiovascular disease - were specially bred to lack a gene called CD44, scientists saw reductions of up to 70 percent in the type of damage to blood-vessel walls associated with heart attacks and stroke. The reduction in disease is one of the greatest effects linked to a single gene yet reported in atherosclerosis. The significance of the observation is further underscored by the fact that CD44 represents a promising target for potential therapies.
The above story is based on materials provided by Wistar Institute. Note: Materials may be edited for content and length.
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