Featured Research

from universities, journals, and other organizations

Landmark Smallpox Vaccine Study Underway

Date:
November 7, 2001
Source:
University Of Rochester Medical Center
Summary:
Volunteers are lining up this week to be vaccinated against smallpox, a once routine occurrence now considered extraordinary yet necessary because of recent events.

Volunteers are lining up this week to be vaccinated against smallpox, a once routine occurrence now considered extraordinary yet necessary because of recent events.

Related Articles


A total of 684 healthy individuals will participate in the study in an effort to increase the number of available doses from existing stocks of smallpox vaccine. Taking part are Saint Louis University, Baylor College of Medicine, the University of Maryland, and the University of Rochester Medical Center. The research study is part of an effort by the U.S. government to extend the supply of the vaccine in case the deadly virus is released as part of a bioterrorism attack. The nation has about 15 million doses on hand; millions more are being made by pharmaceutical firms but are not yet available.

The vaccine contains no smallpox virus, and doctors stress that there is no risk of developing smallpox from the vaccine. Indeed, prior to 1972, getting the vaccine was regarded as a harmless rite of passage: Schoolchildren received the vaccine, then went back to the classroom the same day and compared scabs later in the week. The dime-sized scar that nearly all U.S. citizens older than 32 carry on their upper arms or elsewhere on the body is proof that they received the vaccine as a child. The vaccine is the same one used as part of a worldwide immunization program that eradicated smallpox everywhere but in research laboratories by 1979, an effort led by Rochester alumnus D.A. Henderson.

Study participants are receiving the traditional smallpox vaccine or a diluted form of the vaccine, either one-fifth or one-tenth the traditional dose. Vaccine expert John Treanor, M.D., associate professor of medicine at the University of Rochester and the leader of the Rochester portion of the study, says the clearest sign of successful vaccination will be the development of a dime-sized blister where the injection is given. The blister will scab over and heal within a few weeks, leaving a well recognized scar.

After the initial immunization, patients will be seen every three or four days for at least two weeks as nurses check the condition of the blister or scab and change the bandage. The study will last about two months.

The research teams conducting the study are funded by the National Institutes of Health to develop and test new vaccines for a variety of illnesses, including flu, pneumonia, rotavirus, and whooping cough. The current study focusing on the effectiveness of a diluted form of smallpox vaccine is very similar to a study carried out by the researchers last year on a flu vaccine.


Story Source:

The above story is based on materials provided by University Of Rochester Medical Center. Note: Materials may be edited for content and length.


Cite This Page:

University Of Rochester Medical Center. "Landmark Smallpox Vaccine Study Underway." ScienceDaily. ScienceDaily, 7 November 2001. <www.sciencedaily.com/releases/2001/11/011106084054.htm>.
University Of Rochester Medical Center. (2001, November 7). Landmark Smallpox Vaccine Study Underway. ScienceDaily. Retrieved March 27, 2015 from www.sciencedaily.com/releases/2001/11/011106084054.htm
University Of Rochester Medical Center. "Landmark Smallpox Vaccine Study Underway." ScienceDaily. www.sciencedaily.com/releases/2001/11/011106084054.htm (accessed March 27, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Friday, March 27, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

These Popular Antibiotics Can Cause Permanent Nerve Damage

These Popular Antibiotics Can Cause Permanent Nerve Damage

Newsy (Mar. 27, 2015) — A popular class of antibiotic can leave patients in severe pain and even result in permanent nerve damage. Video provided by Newsy
Powered by NewsLook.com
House Ready to Pass Medicare Doc Bill

House Ready to Pass Medicare Doc Bill

AP (Mar. 26, 2015) — In rare bipartisan harmony, congressional leaders pushed a $214 billion bill permanently blocking physician Medicare cuts toward House passage Thursday, moving lawmakers closer to resolving a problem that has plagued them for years. (March 26) Video provided by AP
Powered by NewsLook.com
What's Different About This Latest Ebola Vaccine

What's Different About This Latest Ebola Vaccine

Newsy (Mar. 26, 2015) — A whole virus Ebola vaccine has been shown to protect monkeys exposed to the virus. Here&apos;s what&apos;s different about this vaccine. Video provided by Newsy
Powered by NewsLook.com
HIV Outbreak Prompts Public Health Emergency In Indiana

HIV Outbreak Prompts Public Health Emergency In Indiana

Newsy (Mar. 26, 2015) — Indiana Gov. Mike Pence says he will bring additional state resources to help stop the epidemic. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins