Featured Research

from universities, journals, and other organizations

Cholesterol Fighting Drugs May Also Have Protective Effects Against Multiple Sclerosis

Date:
October 8, 2002
Source:
American Academy Of Neurology
Summary:
A group of cholesterol-lowering drugs may also effectively interfere with the progression of multiple sclerosis (MS). These drugs, known as statins, greatly reduce hardening of the arteries (atherosclerosis) and heart disease, mainly by their cholesterol and low-density lipoprotein-lowering properties. A study published in the October 8 issue of Neurology, the journal of he American Academy of Neurology, indicates that statins may also have therapeutic potential for a variety of immunity related disorders such as MS, rheumatoid arthritis, type I diabetes and graft-rejection in organ transplantation.

ST. PAUL, MN – A group of cholesterol-lowering drugs may also effectively interfere with the progression of multiple sclerosis (MS). These drugs, known as statins, greatly reduce hardening of the arteries (atherosclerosis) and heart disease, mainly by their cholesterol and low-density lipoprotein-lowering properties. A study published in the October 8 issue of Neurology, the journal of he American Academy of Neurology, indicates that statins may also have therapeutic potential for a variety of immunity related disorders such as MS, rheumatoid arthritis, type I diabetes and graft-rejection in organ transplantation. Researchers from Austria and Germany investigated the impact of statins on a variety of immune responses in MS, comparing the effects with those induced by interferon-beta, an established disease-modifying therapy in MS. Using blood drawn from 74 MS patients and 25 healthy donors, tests were performed in vitro with lovastatin, simvastatin, mevastatin, and interferon alone, and statins plus interferon. "Our study shows that statins modify several molecules of the immune system involved in the disease progression of MS, independent of their use with interferon," notes study author Juan José Archelos, MD, of Karl-Franzens University, Graz, Austria. "The potent anti-inflammatory effects of statins are remarkable, and even more effective when combined with interferon-beta."

This study indicates that these well-established therapeutic agents may be a useful stand-alone or add-on therapy to interferon-beta, with the added advantage of an oral versus injectible delivery. While study results are encouraging, study authors caution that much more research is necessary to establish the precise mechanisms by which statins induce these anti-inflammatory effects.

The American Academy of Neurology, an association of more than 18,000 neurologists and neuroscience professionals, is dedicated to improving patient care through education and research. For more information about the American Academy of Neurology, visit its website at http://www.aan.com.


Story Source:

The above story is based on materials provided by American Academy Of Neurology. Note: Materials may be edited for content and length.


Cite This Page:

American Academy Of Neurology. "Cholesterol Fighting Drugs May Also Have Protective Effects Against Multiple Sclerosis." ScienceDaily. ScienceDaily, 8 October 2002. <www.sciencedaily.com/releases/2002/10/021008065958.htm>.
American Academy Of Neurology. (2002, October 8). Cholesterol Fighting Drugs May Also Have Protective Effects Against Multiple Sclerosis. ScienceDaily. Retrieved September 16, 2014 from www.sciencedaily.com/releases/2002/10/021008065958.htm
American Academy Of Neurology. "Cholesterol Fighting Drugs May Also Have Protective Effects Against Multiple Sclerosis." ScienceDaily. www.sciencedaily.com/releases/2002/10/021008065958.htm (accessed September 16, 2014).

Share This



More Mind & Brain News

Tuesday, September 16, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

FDA Eyes Skin Shocks Used at Mass. School

FDA Eyes Skin Shocks Used at Mass. School

AP (Sep. 15, 2014) — The FDA is considering whether to ban devices used by the Judge Rotenberg Educational Center in Canton, Massachusetts, the only place in the country known to use electrical skin shocks as aversive conditioning for aggressive patients. (Sept. 15) Video provided by AP
Powered by NewsLook.com
Shocker: Journalists Are Utterly Addicted To Coffee

Shocker: Journalists Are Utterly Addicted To Coffee

Newsy (Sep. 13, 2014) — A U.K. survey found that journalists consumed the most amount of coffee, but that's only the tip of the coffee-related statistics iceberg. Video provided by Newsy
Powered by NewsLook.com
'Magic Mushrooms' Could Help Smokers Quit

'Magic Mushrooms' Could Help Smokers Quit

Newsy (Sep. 11, 2014) — In a small study, researchers found that the majority of long-time smokers quit after taking psilocybin pills and undergoing therapy sessions. Video provided by Newsy
Powered by NewsLook.com
'Fat Shaming' Might Actually Cause Weight Gain

'Fat Shaming' Might Actually Cause Weight Gain

Newsy (Sep. 11, 2014) — A study for University College London suggests obese people who are discriminated against gain more weight than those who are not. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins