Featured Research

from universities, journals, and other organizations

Molecular Imaging: Diagnosing Diseases Before Symptoms Strike

Date:
October 31, 2002
Source:
Washington University In St. Louis
Summary:
Researchers at Washington University School of Medicine in St. Louis are developing methods to track molecular events in the body to diagnose disease long before symptoms appear and to predict the effectiveness of drug therapies. The research is under way at the School of Medicine's new Molecular Imaging Center at the Mallinckrodt Institute of Radiology.

Researchers at Washington University School of Medicine in St. Louis are developing methods to track molecular events in the body to diagnose disease long before symptoms appear and to predict the effectiveness of drug therapies. The research is under way at the School of Medicine's new Molecular Imaging Center at the Mallinckrodt Institute of Radiology. The Center is funded by a five-year $9.4 million grant from the National Cancer Institute.

"Molecular imaging combines the latest in imaging technology with the power of molecular biology," says David Piwnica-Worms, M.D., Ph.D., professor of radiology and of molecular biology and pharmacology and director of the new center.

"We believe that molecular imaging will one day enable us to diagnose specific molecular events of cancer, neurologic disease or inflammation earlier in the course of disease, and that this will help doctors identify the most effective therapy for individual patients."

Piwnica-Worms described molecular imaging and research being done at the Center during the 40th annual New Horizons in Science Briefing, sponsored by the Council for the Advancement of Science Writing, held Oct. 27-30 at Washington University in St. Louis.

Investigators at the Center are using molecular imaging to study protein-protein interactions, immune cells attacking a tumor, and the course of a viral infection and its response to antiviral therapy. Other researchers are developing a means to noninvasively predict the effectiveness of particular chemotherapy drugs in patients with advanced lung cancer. The investigators are studying lung tumors for ways to image the activity of a protein that pumps certain anticancer drugs out of tumor cells, rendering the drugs ineffective for those individuals.

Positron emission tomography (PET) is one example of molecular imaging technology already in use clinically. PET scans are used, for instance, to detect the spread of certain cancers. Patients are given a form of sugar -- glucose -- that contains a weak radioactive label. The labeled sugar is taken up more rapidly by tumor cells than by normal cells because the tumor cells are growing at a faster rate. PET-scan imaging reveals this higher level of uptake, thereby providing a non-surgical means of detecting an otherwise hidden tumor.

Researchers at Washington University's Molecular Imaging Center are developing new applications for existing technologies, such as PET, and exploring new methods of molecular imaging using near-infrared fluorescence and bioluminescence probes.


Story Source:

The above story is based on materials provided by Washington University In St. Louis. Note: Materials may be edited for content and length.


Cite This Page:

Washington University In St. Louis. "Molecular Imaging: Diagnosing Diseases Before Symptoms Strike." ScienceDaily. ScienceDaily, 31 October 2002. <www.sciencedaily.com/releases/2002/10/021031074529.htm>.
Washington University In St. Louis. (2002, October 31). Molecular Imaging: Diagnosing Diseases Before Symptoms Strike. ScienceDaily. Retrieved July 24, 2014 from www.sciencedaily.com/releases/2002/10/021031074529.htm
Washington University In St. Louis. "Molecular Imaging: Diagnosing Diseases Before Symptoms Strike." ScienceDaily. www.sciencedaily.com/releases/2002/10/021031074529.htm (accessed July 24, 2014).

Share This




More Health & Medicine News

Thursday, July 24, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

New Painkiller Designed To Discourage Abuse: Will It Work?

New Painkiller Designed To Discourage Abuse: Will It Work?

Newsy (July 24, 2014) The FDA approved Targiniq ER on Wednesday, a painkiller designed to keep users from abusing it. Like any new medication, however, it has doubters. Video provided by Newsy
Powered by NewsLook.com
Doctor At Forefront Of Fighting Ebola Outbreak Gets Ebola

Doctor At Forefront Of Fighting Ebola Outbreak Gets Ebola

Newsy (July 24, 2014) Sheik Umar Khan has treated many of the people infected in the Ebola outbreak, and now he's become one of them. Video provided by Newsy
Powered by NewsLook.com
Condemned Man's US Execution Takes Nearly Two Hours

Condemned Man's US Execution Takes Nearly Two Hours

AFP (July 24, 2014) America's death penalty debate raged Thursday after it took nearly two hours for Arizona to execute a prisoner who lost a Supreme Court battle challenging the experimental lethal drug cocktail. Duration: 00:55 Video provided by AFP
Powered by NewsLook.com
Can Watching TV Make You Feel Like A Failure?

Can Watching TV Make You Feel Like A Failure?

Newsy (July 24, 2014) A study by German researchers claims watching TV while you're stressed out can make you feel guilty and like a failure. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

    Health News

      Environment News

        Technology News



          Save/Print:
          Share:

          Free Subscriptions


          Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

          Get Social & Mobile


          Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

          Have Feedback?


          Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
          Mobile: iPhone Android Web
          Follow: Facebook Twitter Google+
          Subscribe: RSS Feeds Email Newsletters
          Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins