Featured Research

from universities, journals, and other organizations

Molecular Imaging: Diagnosing Diseases Before Symptoms Strike

Date:
October 31, 2002
Source:
Washington University In St. Louis
Summary:
Researchers at Washington University School of Medicine in St. Louis are developing methods to track molecular events in the body to diagnose disease long before symptoms appear and to predict the effectiveness of drug therapies. The research is under way at the School of Medicine's new Molecular Imaging Center at the Mallinckrodt Institute of Radiology.

Researchers at Washington University School of Medicine in St. Louis are developing methods to track molecular events in the body to diagnose disease long before symptoms appear and to predict the effectiveness of drug therapies. The research is under way at the School of Medicine's new Molecular Imaging Center at the Mallinckrodt Institute of Radiology. The Center is funded by a five-year $9.4 million grant from the National Cancer Institute.

Related Articles


"Molecular imaging combines the latest in imaging technology with the power of molecular biology," says David Piwnica-Worms, M.D., Ph.D., professor of radiology and of molecular biology and pharmacology and director of the new center.

"We believe that molecular imaging will one day enable us to diagnose specific molecular events of cancer, neurologic disease or inflammation earlier in the course of disease, and that this will help doctors identify the most effective therapy for individual patients."

Piwnica-Worms described molecular imaging and research being done at the Center during the 40th annual New Horizons in Science Briefing, sponsored by the Council for the Advancement of Science Writing, held Oct. 27-30 at Washington University in St. Louis.

Investigators at the Center are using molecular imaging to study protein-protein interactions, immune cells attacking a tumor, and the course of a viral infection and its response to antiviral therapy. Other researchers are developing a means to noninvasively predict the effectiveness of particular chemotherapy drugs in patients with advanced lung cancer. The investigators are studying lung tumors for ways to image the activity of a protein that pumps certain anticancer drugs out of tumor cells, rendering the drugs ineffective for those individuals.

Positron emission tomography (PET) is one example of molecular imaging technology already in use clinically. PET scans are used, for instance, to detect the spread of certain cancers. Patients are given a form of sugar -- glucose -- that contains a weak radioactive label. The labeled sugar is taken up more rapidly by tumor cells than by normal cells because the tumor cells are growing at a faster rate. PET-scan imaging reveals this higher level of uptake, thereby providing a non-surgical means of detecting an otherwise hidden tumor.

Researchers at Washington University's Molecular Imaging Center are developing new applications for existing technologies, such as PET, and exploring new methods of molecular imaging using near-infrared fluorescence and bioluminescence probes.


Story Source:

The above story is based on materials provided by Washington University In St. Louis. Note: Materials may be edited for content and length.


Cite This Page:

Washington University In St. Louis. "Molecular Imaging: Diagnosing Diseases Before Symptoms Strike." ScienceDaily. ScienceDaily, 31 October 2002. <www.sciencedaily.com/releases/2002/10/021031074529.htm>.
Washington University In St. Louis. (2002, October 31). Molecular Imaging: Diagnosing Diseases Before Symptoms Strike. ScienceDaily. Retrieved December 22, 2014 from www.sciencedaily.com/releases/2002/10/021031074529.htm
Washington University In St. Louis. "Molecular Imaging: Diagnosing Diseases Before Symptoms Strike." ScienceDaily. www.sciencedaily.com/releases/2002/10/021031074529.htm (accessed December 22, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Monday, December 22, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Christmas Kissing Good for Health

Christmas Kissing Good for Health

Reuters - Innovations Video Online (Dec. 22, 2014) Scientists in Amsterdam say couples transfer tens of millions of microbes when they kiss, encouraging healthy exposure to bacteria. Suzannah Butcher reports. Video provided by Reuters
Powered by NewsLook.com
Brain-Dwelling Tapeworm Reveals Genetic Secrets

Brain-Dwelling Tapeworm Reveals Genetic Secrets

Reuters - Innovations Video Online (Dec. 22, 2014) Cambridge scientists have unravelled the genetic code of a rare tapeworm that lived inside a patient's brain for at least four year. Researchers hope it will present new opportunities to diagnose and treat this invasive parasite. Matthew Stock reports. Video provided by Reuters
Powered by NewsLook.com
Touch-Free Smart Phone Empowers Mobility-Impaired

Touch-Free Smart Phone Empowers Mobility-Impaired

Reuters - Innovations Video Online (Dec. 21, 2014) A touch-free phone developed in Israel enables the mobility-impaired to operate smart phones with just a movement of the head. Suzannah Butcher reports. Video provided by Reuters
Powered by NewsLook.com
Earthworms Provide Cancer-Fighting Bacteria

Earthworms Provide Cancer-Fighting Bacteria

Reuters - Innovations Video Online (Dec. 21, 2014) Polish scientists isolate bacteria from earthworm intestines which they say may be used in antibiotics and cancer treatments. Suzannah Butcher reports. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins