Featured Research

from universities, journals, and other organizations

Aspirin Inhibits Ovarian Cancer Growth, Lab Study Finds

Date:
November 7, 2002
Source:
University Of South Florida Health Sciences Center
Summary:
Aspirin may reduce ovarian cancer growth, a laboratory study by the USF College of Medicine has shown. The study, published in the October issue of the journal Obstetrics and Gynecology, demonstrated that aspirin inhibited ovarian tumor cell growth by as much as 68 percent. The higher the dosage of aspirin added to the culture of ovarian cancer cells, the more growth inhibition was observed.

Tampa, FL (Nov. 5, 2002) -- Aspirin may reduce ovarian cancer growth, a laboratory study by the USF College of Medicine has shown.

The study, published in the October issue of the journal Obstetrics and Gynecology, demonstrated that aspirin inhibited ovarian tumor cell growth by as much as 68 percent. The higher the dosage of aspirin added to the culture of ovarian cancer cells, the more growth inhibition was observed.

The researchers also found that combining aspirin with a monoclonal antibody specific for the HER-2/neu protein created even greater suppression of growth than treating the tumor cells with aspirin alone. This combination decreased ovarian cancer cell growth by 84 percent.

HER-2/neu is a receptor protein on the tumor cell surface that binds to a substance that stimulates growth. The protein is elevated in a third of ovarian cancers.

Jeanne Becker, PhD, an associate professor in the Department of Obstetrics and Gynecology, was senior author for the study, along with co-author Janet Drake, MD, formerly a gynecologic oncology fellow at USF. Last year, Dr. Becker's laboratory demonstrated that aspirin inhibits the growth of endometrial cancer by promoting programmed cell death, or apoptosis.

USF continues its preclinical studies to determine how aspirin inhibits tumor cell growth. Dr. Becker said much more research must be done, including patient studies, before women are urged to begin taking aspirin to stave off ovarian cancer.

Because there are few early symptoms, ovarian cancer is often diagnosed in advanced stages and kills more women than any other gynecological cancer. The American Cancer Society estimates that in 2002 nearly 14,000 women will die of ovarian cancer, and 23,300 new cases will be diagnosed.


Story Source:

The above story is based on materials provided by University Of South Florida Health Sciences Center. Note: Materials may be edited for content and length.


Cite This Page:

University Of South Florida Health Sciences Center. "Aspirin Inhibits Ovarian Cancer Growth, Lab Study Finds." ScienceDaily. ScienceDaily, 7 November 2002. <www.sciencedaily.com/releases/2002/11/021107074244.htm>.
University Of South Florida Health Sciences Center. (2002, November 7). Aspirin Inhibits Ovarian Cancer Growth, Lab Study Finds. ScienceDaily. Retrieved July 28, 2014 from www.sciencedaily.com/releases/2002/11/021107074244.htm
University Of South Florida Health Sciences Center. "Aspirin Inhibits Ovarian Cancer Growth, Lab Study Finds." ScienceDaily. www.sciencedaily.com/releases/2002/11/021107074244.htm (accessed July 28, 2014).

Share This




More Health & Medicine News

Monday, July 28, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Deadly Ebola Virus Threatens West Africa

Deadly Ebola Virus Threatens West Africa

AP (July 28, 2014) West African nations and international health organizations are working to contain the largest Ebola outbreak in history. It's one of the deadliest diseases known to man, but the CDC says it's unlikely to spread in the U.S. (July 28) Video provided by AP
Powered by NewsLook.com
$15B Deal on Vets' Health Care Reached

$15B Deal on Vets' Health Care Reached

AP (July 28, 2014) A bipartisan deal to improve veterans health care would authorize at least $15 billion in emergency spending to fix a veterans program scandalized by long patient wait times and falsified records. (July 28) Video provided by AP
Powered by NewsLook.com
Two Americans Contract Ebola in Liberia

Two Americans Contract Ebola in Liberia

Reuters - US Online Video (July 28, 2014) Two American aid workers in Liberia test positive for Ebola while working to combat the deadliest outbreak of the virus ever. Linda So reports. Video provided by Reuters
Powered by NewsLook.com
Traditional African Dishes Teach Healthy Eating

Traditional African Dishes Teach Healthy Eating

AP (July 28, 2014) Classes are being offered nationwide to encourage African Americans to learn about cooking fresh foods based on traditional African cuisine. The program is trying to combat obesity, heart disease and other ailments often linked to diet. (July 28) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins