Featured Research

from universities, journals, and other organizations

Receptor Found That Guides Nerve Cells To Their Final Connecting Sites

Date:
March 20, 2003
Source:
Salk Institute
Summary:
A Salk Institute research team has discovered a receptor-protein interaction that guides nerve cells along specific pathways.

La Jolla, Calif. -- In the developing brain, nerve cells make connections with one another by extending processes, often over long distances.

The growing tips of these nerve cell processes are guided to their ultimate connection sites by molecular cues in the environment.

A Salk Institute research team has discovered a receptor-protein interaction that guides nerve cells along specific pathways.

John Thomas, professor of molecular neurobiology, working on the fruit fly Drosophila, found that a protein called Wnt5, a member of a large family of signaling molecules, binds to a receptor called Derailed present on the surface of growing nerve cells.

This binding guides the tips of these nerve cells to their final destination by preventing them from entering the wrong pathway.

This mechanism appears especially important for nerve cells that extend processes across the midline to make connections on the opposite side of the nervous system, a prominent class of nerve cells also found in vertebrates.

This research could have implications for understanding birth defects as well as the regeneration of nerve cells. The study is published in the March 17 edition of Nature.


Story Source:

The above story is based on materials provided by Salk Institute. Note: Materials may be edited for content and length.


Cite This Page:

Salk Institute. "Receptor Found That Guides Nerve Cells To Their Final Connecting Sites." ScienceDaily. ScienceDaily, 20 March 2003. <www.sciencedaily.com/releases/2003/03/030320073551.htm>.
Salk Institute. (2003, March 20). Receptor Found That Guides Nerve Cells To Their Final Connecting Sites. ScienceDaily. Retrieved September 17, 2014 from www.sciencedaily.com/releases/2003/03/030320073551.htm
Salk Institute. "Receptor Found That Guides Nerve Cells To Their Final Connecting Sites." ScienceDaily. www.sciencedaily.com/releases/2003/03/030320073551.htm (accessed September 17, 2014).

Share This



More Health & Medicine News

Wednesday, September 17, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

President To Send 3,000 Military Personnel To Fight Ebola

President To Send 3,000 Military Personnel To Fight Ebola

Newsy (Sep. 16, 2014) President Obama is expected to send 3,000 troops to West Africa as part of the effort to contain Ebola's spread. Video provided by Newsy
Powered by NewsLook.com
Man Floats for 31 Hours in Gulf Waters

Man Floats for 31 Hours in Gulf Waters

AP (Sep. 16, 2014) A Texas man is lucky to be alive after he and three others floated for more than a day in the Gulf of Mexico when their boat sank during a fishing trip. (Sept. 16) Video provided by AP
Powered by NewsLook.com
Ivorians Abandon Monkey Pets in Fear Over Ebola Virus

Ivorians Abandon Monkey Pets in Fear Over Ebola Virus

AFP (Sep. 16, 2014) Since the arrival of Ebola in Ivory Coast, Ivorians have been abandoning their pets, particularly monkeys, in the fear that they may transmit the virus. Duration: 00:47 Video provided by AFP
Powered by NewsLook.com
Study Links Male-Pattern Baldness To Prostate Cancer

Study Links Male-Pattern Baldness To Prostate Cancer

Newsy (Sep. 16, 2014) New findings suggest men with a certain type of baldness at age 45 are 39 percent more likely to develop aggressive prostate cancer. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

    Environment News

      Technology News



      Save/Print:
      Share:

      Free Subscriptions


      Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

      Get Social & Mobile


      Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

      Have Feedback?


      Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
      Mobile: iPhone Android Web
      Follow: Facebook Twitter Google+
      Subscribe: RSS Feeds Email Newsletters
      Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins