Featured Research

from universities, journals, and other organizations

Deciphering How Arteries Contribute To Hypertension

Date:
June 11, 2003
Source:
National Institute Of Standards And Technology
Summary:
National Insitute of Standards and Technology (NIST) scientists are taking their knowledge of mechanical tensile strength tests in metals and composites and applying it to medical research problems. Doctors long have known that babies born with congenital heart defects at higher altitudes have an increased risk of developing complications, such as pulmonary hypertension. Could there be some way to trick the arterial walls so that they wouldn't stiffen under increased blood pressure?

National Insitute of Standards and Technology (NIST) scientists are taking their knowledge of mechanical tensile strength tests in metals and composites and applying it to medical research problems. Doctors long have known that babies born with congenital heart defects at higher altitudes have an increased risk of developing complications, such as pulmonary hypertension. Could there be some way to trick the arterial walls so that they wouldn't stiffen under increased blood pressure?

Working with the Children's Hospital and University of Colorado Health Sciences Center in Denver, NIST researchers have used rat arteries--both normal and hypertensive--supplied by the university center and placed them in a mechanical stress tester. The tester holds a small disc-shaped sample of the arterial tissue that is slowly stretched by pumping a special liquid against the back of the disc. The pressure of the liquid causes a bubble to form on the front of the disc. The shape of the resulting bubble helps the researchers determine details about the tissues' elasticity, strength, stiffness and other properties.

" Hypertensive tissue should be stiffer, so we will get less inflation with the same amount of pressure," says NIST researcher Elizabeth Drexler. "What we want to know is what it is in the artery that causes it to stiffen. Is it more collagen? Is it the smooth muscle cells? Perhaps we could give the muscle cell a signal not to produce more collagen." So far they have studied 20 rat arteries and plan to study 20 more, along with some calf arteries. A preliminary report that verifies their test method appears in the May/June issue of the NIST Journal of Research.


Story Source:

The above story is based on materials provided by National Institute Of Standards And Technology. Note: Materials may be edited for content and length.


Cite This Page:

National Institute Of Standards And Technology. "Deciphering How Arteries Contribute To Hypertension." ScienceDaily. ScienceDaily, 11 June 2003. <www.sciencedaily.com/releases/2003/06/030611080734.htm>.
National Institute Of Standards And Technology. (2003, June 11). Deciphering How Arteries Contribute To Hypertension. ScienceDaily. Retrieved September 19, 2014 from www.sciencedaily.com/releases/2003/06/030611080734.htm
National Institute Of Standards And Technology. "Deciphering How Arteries Contribute To Hypertension." ScienceDaily. www.sciencedaily.com/releases/2003/06/030611080734.htm (accessed September 19, 2014).

Share This



More Matter & Energy News

Friday, September 19, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Virtual Reality Headsets Unveiled at Tokyo Game Show

Virtual Reality Headsets Unveiled at Tokyo Game Show

AFP (Sep. 18, 2014) Several companies unveiled virtual reality headsets at the Tokyo Game Show, Asia's largest digital entertainment exhibition. Duration: 00:48 Video provided by AFP
Powered by NewsLook.com
Apple's iOS8 Includes New 'Killswitch' To Curb Theft

Apple's iOS8 Includes New 'Killswitch' To Curb Theft

Newsy (Sep. 18, 2014) Apple's new operating system, iOS 8, comes with Apple's killswitch feature already activated, unlike all the models before it. Video provided by Newsy
Powered by NewsLook.com
Stocks Hit All-Time High as Fed Holds Steady

Stocks Hit All-Time High as Fed Holds Steady

AP (Sep. 17, 2014) The Federal Reserve signaled Wednesday that it plans to keep a key interest rate at a record low because a broad range of U.S. economic measures remain subpar. Stocks hit an all-time high on the news. (Sept. 17) Video provided by AP
Powered by NewsLook.com
Space Race Pits Bezos Vs Musk

Space Race Pits Bezos Vs Musk

Reuters - Business Video Online (Sep. 16, 2014) Amazon CEO Jeff Bezos' startup will team up with Boeing and Lockheed to develop rocket engines as Elon Musk races to have his rockets certified. Fred Katayama reports. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins