Featured Research

from universities, journals, and other organizations

Aspirin May Not Be Strong Enough To Prevent Clots In Some Heart Patients

Date:
November 13, 2003
Source:
Johns Hopkins Medical Institutions
Summary:
While an aspirin a day helps keep a heart attack at bay, it may need reinforcement to totally prevent blood clots among patients with chest pain, a Johns Hopkins study shows.

While an aspirin a day helps keep a heart attack at bay, it may need reinforcement to totally prevent blood clots among patients with chest pain, a Johns Hopkins study shows.

Related Articles


Researchers took blood samples from 33 patients hospitalized for chest pain at Johns Hopkins Bayview Medical Center. Eighteen patients had acute coronary syndrome, or heart-disease-related chest pain, and 15 had non-cardiac chest pain. All took aspirin at 81 to 325 milligrams per day.

The Hopkins team treated the samples with very low doses of ADP and epinephrine – medications that allow platelets, tiny disk-shaped structures within the blood, to clump together. They found that despite treatment with aspirin, platelets clotted together 5 percent to 10 percent more among the patients with heart disease than those without.

The work is to be presented Nov. 10 at the American Heart Association's 76th Scientific Sessions in Orlando, Fla.

"Even though these patients were receiving aspirin therapy, they still had very active platelets," says Marlene S. Williams, M.D., lead author of the study and assistant professor of medicine. The more the platelets clump together, the higher the chance of a clot forming, leading to a heart attack, she says.

Patients already taking daily aspirin should continue, Williams says. Her further studies will investigate the addition of other anti-clotting agents to aspirin therapy, and the study of abnormal genes that might affect platelet function.

###

The study was funded by the National Institutes of Health. Coauthors were David E. Bush, M.D., and Thomas Kickler, M.D.

Abstract #1756: Williams, M.S., "Platelet Hyperreactivity Is Present in Acute Coronary Syndromes Despite Treatment with Aspirin."

Related links:

Johns Hopkins' Division of Cardiologyhttp://www.hopkinsmedicine.org/cardiology/

American Heart Association - 76th Scientific Sessionshttp://www.scientificsessions.org/


Story Source:

The above story is based on materials provided by Johns Hopkins Medical Institutions. Note: Materials may be edited for content and length.


Cite This Page:

Johns Hopkins Medical Institutions. "Aspirin May Not Be Strong Enough To Prevent Clots In Some Heart Patients." ScienceDaily. ScienceDaily, 13 November 2003. <www.sciencedaily.com/releases/2003/11/031113070022.htm>.
Johns Hopkins Medical Institutions. (2003, November 13). Aspirin May Not Be Strong Enough To Prevent Clots In Some Heart Patients. ScienceDaily. Retrieved November 28, 2014 from www.sciencedaily.com/releases/2003/11/031113070022.htm
Johns Hopkins Medical Institutions. "Aspirin May Not Be Strong Enough To Prevent Clots In Some Heart Patients." ScienceDaily. www.sciencedaily.com/releases/2003/11/031113070022.htm (accessed November 28, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Friday, November 28, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Ebola Leaves Orphans Alone in Sierra Leone

Ebola Leaves Orphans Alone in Sierra Leone

AFP (Nov. 27, 2014) — The Ebola epidemic sweeping Sierra Leone is having a profound effect on the country's children, many of whom have been left without any family members to support them. Duration: 01:02 Video provided by AFP
Powered by NewsLook.com
Experimental Ebola Vaccine Shows Promise In Human Trial

Experimental Ebola Vaccine Shows Promise In Human Trial

Newsy (Nov. 27, 2014) — A recent test of a prototype Ebola vaccine generated an immune response to the disease in subjects. Video provided by Newsy
Powered by NewsLook.com
Pet Dogs to Be Used in Anti-Ageing Trial

Pet Dogs to Be Used in Anti-Ageing Trial

Reuters - Innovations Video Online (Nov. 26, 2014) — Researchers in the United States are preparing to discover whether a drug commonly used in human organ transplants can extend the lifespan and health quality of pet dogs. Video provided by Reuters
Powered by NewsLook.com
Today's Prostheses Are More Capable Than Ever

Today's Prostheses Are More Capable Than Ever

Newsy (Nov. 26, 2014) — Advances in prosthetics are making replacement body parts stronger and more lifelike than they’ve ever been. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins