Featured Research

from universities, journals, and other organizations

Researchers Begin Promising New Trial To Fight Colorectal Cancer

Date:
March 12, 2004
Source:
New York University Medical Center And School Of Medicine
Summary:
New York University School of Medicine investigators are leading a national study, called TREE-2, which will evaluate the safety and efficacy of three regimens of Eloxatin plus fluoropymidine, plus Avastin as first-line treatment of patients with advanced colorectal cancer.

NEW YORK, March 10, 2004 – New York University School of Medicine investigators are leading a national study, called TREE-2, which will evaluate the safety and efficacy of three regimens of Eloxatin™ plus fluoropymidine, plus Avastin™ as first-line treatment of patients with advanced colorectal cancer. Two hundred and ten patients will be enrolled at 80 sites in the United States.

Related Articles


This new study is based on promising data presented at the 2003 American Society of Clinical Oncology (ASCO) meeting demonstrating an incremental survival benefit when Avastin™ was added to a standard first-line colon cancer treatment regimen called IFL (Irinotecan, 5-FU, Leucovorin). At the same meeting, it was reported that patients treated with Eloxatin, used in combination with the fluoropymidine 5-FU (FOLFOX), survived longer than those treated with IFL in a head-to-head comparison study. Eloxatin? is manufactured by Sanofy-Synthelabo and Genentech manufactures Avastin?.

"The findings from this study have the potential to affect the standard of care for metastatic colorectal cancer," said Howard Hochster, M.D, lead investigator of the TREE 2 study. "We are making focused efforts to find the most effective therapeutic option currently available for treatment of colorectal cancer. This study will combine an effective anti-angiogenesis antibody with the best possible chemotherapy. We are also looking at ways of making the oxaliplatin-based chemotherapy regimens more user friendly for the patient."

It is hoped that this new drug regimen will ultimately improve the treatment and survival rate of patients with colorectal cancer, the second leading cause of cancer deaths in the United States. Approximately 150,000 new cases are diagnosed each year and in 2003 nearly 60,000 deaths were attributed to the disease.


Story Source:

The above story is based on materials provided by New York University Medical Center And School Of Medicine. Note: Materials may be edited for content and length.


Cite This Page:

New York University Medical Center And School Of Medicine. "Researchers Begin Promising New Trial To Fight Colorectal Cancer." ScienceDaily. ScienceDaily, 12 March 2004. <www.sciencedaily.com/releases/2004/03/040311071225.htm>.
New York University Medical Center And School Of Medicine. (2004, March 12). Researchers Begin Promising New Trial To Fight Colorectal Cancer. ScienceDaily. Retrieved March 2, 2015 from www.sciencedaily.com/releases/2004/03/040311071225.htm
New York University Medical Center And School Of Medicine. "Researchers Begin Promising New Trial To Fight Colorectal Cancer." ScienceDaily. www.sciencedaily.com/releases/2004/03/040311071225.htm (accessed March 2, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Monday, March 2, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Rehab Robot Helps Restore Damaged Muscles and Nerves

Rehab Robot Helps Restore Damaged Muscles and Nerves

Reuters - Innovations Video Online (Mar. 1, 2015) A rehabilitation robot prototype to help restore deteriorated nerves and muscles using electromyography and computer games. Ben Gruber reports. Video provided by Reuters
Powered by NewsLook.com
How Facebook Use Can Lead To Depression

How Facebook Use Can Lead To Depression

Newsy (Mar. 1, 2015) Margaret Duffy of the University of Missouri talks about her study on the social network and the envy and depression that Facebook use can cause. Video provided by Newsy
Powered by NewsLook.com
Could a $34 Smartphone Device Improve HIV Diagnosis in Africa?

Could a $34 Smartphone Device Improve HIV Diagnosis in Africa?

Reuters - Innovations Video Online (Feb. 27, 2015) A dongle that plugs into a Smartphone mimics a lab-based blood test for HIV and syphilis and can detect the diseases in 15 minutes, say researchers. Tara Cleary reports. Video provided by Reuters
Powered by NewsLook.com
Doctor Says Head Transplants Possible Within Two Years

Doctor Says Head Transplants Possible Within Two Years

Buzz60 (Feb. 27, 2015) An Italian doctor is saying he could stick someone&apos;s head onto someone else&apos;s body. Patrick Jones (@Patrick_E_Jones) reports. Video provided by Buzz60
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins