Featured Research

from universities, journals, and other organizations

Yale Scientists Visualize Molecular Detail Of RNA Splicing Complex

Date:
June 3, 2004
Source:
Yale University
Summary:
Scientists in the department of molecular biophysics and biochemistry at Yale revealed the crystal structure of the first described enzymatic RNA - what it looks like and how it reacts - in the journal Nature.

New Haven, Conn. – Scientists in the department of molecular biophysics and biochemistry at Yale revealed the crystal structure of the first described enzymatic RNA - what it looks like and how it reacts - in the journal Nature.

Related Articles


Scott Strobel, professor and principal investigator of the study and his research team at Yale, used X-ray crystallography to image the self-splicing group-I intron and the associations it makes as it reacts. The image shows an interaction with metal ions and the alignment of the RNA molecule segments.

"The structure reveals how RNA, which is chemically very different from protein, is able to use metal ions to achieve a very similar reaction mechanism," said Scott Strobel, "This argues for an evolutionarily ancient mechanism."

Over twenty years ago scientists discovered that RNA, and not just protein, could act like an enzyme. The Nobel Prize in Chemistry in 1989 was awarded to Thomas Cech at the University of Colorado and Sidney Altman at Yale at for this revolutionary discovery.

"This is the first RNA splicing complex to be visualized in molecular detail," said Strobel. "Now we can finally see what it looks like and how it reacts."


Story Source:

The above story is based on materials provided by Yale University. Note: Materials may be edited for content and length.


Cite This Page:

Yale University. "Yale Scientists Visualize Molecular Detail Of RNA Splicing Complex." ScienceDaily. ScienceDaily, 3 June 2004. <www.sciencedaily.com/releases/2004/06/040603070421.htm>.
Yale University. (2004, June 3). Yale Scientists Visualize Molecular Detail Of RNA Splicing Complex. ScienceDaily. Retrieved March 1, 2015 from www.sciencedaily.com/releases/2004/06/040603070421.htm
Yale University. "Yale Scientists Visualize Molecular Detail Of RNA Splicing Complex." ScienceDaily. www.sciencedaily.com/releases/2004/06/040603070421.htm (accessed March 1, 2015).

Share This


More From ScienceDaily



More Matter & Energy News

Sunday, March 1, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Elon Musk's Hyperloop Moves Forward

Elon Musk's Hyperloop Moves Forward

Buzz60 (Feb. 27, 2015) Zipping around at 800-miles an hour is coming closer to reality in California. An entire town is being built around Elon Musk&apos;s Hyperloop concept and it wants you to stop in for a ride when it&apos;s ready. Brett Larson is on board. Video provided by Buzz60
Powered by NewsLook.com
Vibrating Bicycle Senses Traffic

Vibrating Bicycle Senses Traffic

Reuters - Innovations Video Online (Feb. 26, 2015) Dutch scientists have developed a smart bicycle that uses sensors, wireless technology and video to warn riders of traffic dangers. Ben Gruber reports. Video provided by Reuters
Powered by NewsLook.com
In Japan, Robot Dogs Are for Life -- And Death

In Japan, Robot Dogs Are for Life -- And Death

AFP (Feb. 25, 2015) Robot dogs are the perfect pet for some in Japan who go to repairmen-turned-vets when their pooch breaks down - while a full Buddhist funeral ceremony awaits those who don&apos;t make it. Duration: 02:40 Video provided by AFP
Powered by NewsLook.com
London Show Dissects History of Forensic Science

London Show Dissects History of Forensic Science

AFP (Feb. 25, 2015) Forensic science, which has fascinated generations with its unravelling of gruesome crime mysteries, is being put under the microscope in an exhibition of real criminal investigations in London. Duration: 00:53 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Space & Time

Matter & Energy

Computers & Math

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins