Featured Research

from universities, journals, and other organizations

Researcher Issues Caution On Live Virus Vaccines

Date:
June 18, 2004
Source:
New York Medical College
Summary:
A New York Medical College microbiologist warns that live virus vaccines to prevent infectious diseases like West Nile virus and yellow fever could have dire consequences.

VALHALLA, N.Y., June 18, 2004 -- A New York Medical College microbiologist warns that live virus vaccines to prevent infectious diseases like West Nile virus and yellow fever could have dire consequences. Should one of the vaccine flaviviruses recombine with a wild-type virus, a new microbe with potentially undesirable properties could result, according to Stephen J. Seligman, M.D., research professor of microbiology and immunology.

Related Articles


His paper, "Live flavivirus vaccines: reasons for caution" appears as a rapid review article in the June 19, 2004, issue of the journal Lancet. Co-author is Ernest A. Gould, Ph.D., of CEH-Oxford in the UK.

Flaviviruses, which can recombine within species and may recombine between species, also include dengue, Japanese encephalitis and tick-borne encephalitis. They cause substantial sickness and death each year. Although live-virus vaccines offer great promise in terms of cost and efficacy, their use should be approved by an international authority due to safety concerns, the authors write.

The article lists five main lessons learned from other live virus vaccines:

* reversion of vaccine strains to increased virulence;

* development of disease in individuals with compromised immune systems;

* birth defects, particularly if the vaccine is given in the first trimester;

* spread of vaccine strains to unvaccinated persons and;

* the discovery of new, previously undetermined complications.


Story Source:

The above story is based on materials provided by New York Medical College. Note: Materials may be edited for content and length.


Cite This Page:

New York Medical College. "Researcher Issues Caution On Live Virus Vaccines." ScienceDaily. ScienceDaily, 18 June 2004. <www.sciencedaily.com/releases/2004/06/040618063335.htm>.
New York Medical College. (2004, June 18). Researcher Issues Caution On Live Virus Vaccines. ScienceDaily. Retrieved January 25, 2015 from www.sciencedaily.com/releases/2004/06/040618063335.htm
New York Medical College. "Researcher Issues Caution On Live Virus Vaccines." ScienceDaily. www.sciencedaily.com/releases/2004/06/040618063335.htm (accessed January 25, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Sunday, January 25, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Disneyland Measles Outbreak Spreads To 5 States

Disneyland Measles Outbreak Spreads To 5 States

Newsy (Jan. 24, 2015) Much of the Disneyland measles outbreak is being blamed on the anti-vaccination movement. The CDC encourages just about everyone get immunized. Video provided by Newsy
Powered by NewsLook.com
Growing Measles Outbreak Worries Calif. Parents

Growing Measles Outbreak Worries Calif. Parents

AP (Jan. 23, 2015) Public health officials are rushing to contain a measles outbreak that has sickened 70 people across 6 states and Mexico. The AP&apos;s Raquel Maria Dillon has more. (Jan. 23) Video provided by AP
Powered by NewsLook.com
Smart Wristband to Shock Away Bad Habits

Smart Wristband to Shock Away Bad Habits

Reuters - Innovations Video Online (Jan. 23, 2015) A Boston start-up is developing a wristband they say will help users break bad habits by jolting them with an electric shock. Ben Gruber reports. Video provided by Reuters
Powered by NewsLook.com
This Is What It's Like To Date A Med Student

This Is What It's Like To Date A Med Student

BuzzFeed (Jan. 23, 2015) Dating is now speed-dating... or studying. Video provided by BuzzFeed
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins