Featured Research

from universities, journals, and other organizations

Bacteria-Killing Vs. Bacteria-Inhibiting Drugs In Treating Infections

Date:
October 22, 2004
Source:
Infectious Diseases Society Of America
Summary:
When treating an infection, physicians may face a choice between using a bactericidal (bacteria-killing) drug, a bacteriostatic (bacteria-inhibiting) drug or a combination of the two. The solution is not always obvious, particularly since a drug that is bactericidal for one strain of bacteria may only inhibit the growth of another strain, according to an article in the November 1 issue of Clinical Infectious Diseases.

When treating an infection, physicians may face a choice between using a bactericidal (bacteria-killing) drug, a bacteriostatic (bacteria-inhibiting) drug or a combination of the two. The solution is not always obvious, particularly since a drug that is bactericidal for one strain of bacteria may only inhibit the growth of another strain, according to an article in the November 1 issue of Clinical Infectious Diseases, now available online.

Although it might seem logical that bactericidal drugs would be preferable to bacteriostatic drugs, the type of infection is important in determining which kind of drug to use. Endocarditis seems to be best treated by bactericidal drugs. Meningitis is another candidate for bactericidal drugs. Strikingly, a bacteriostatic drug can antagonize the action of a bactericidal one in the treatment of meningitis. In treating urinary tract infections and preventing staphylococcal wound infections, studies have shown that bacteriostatic drugs work as well as bactericidal drugs.

In central nervous system infections, a rapidly bactericidal drug can release bacterial products that stimulate inflammation. For this reason, it is recommended that corticosteroids be given at the same time as a bactericidal antibiotic for bacterial meningitis. Certain bacteriostatic drugs may be preferable in cases of streptococcal and clostridial gangrene, because they inhibit the production of the toxins that cause much of the morbidity.

Some infectious disease physicians wrongly believe that bacteria-killing drugs are automatically preferable to those that inhibit bacterial growth, according to Dr. Robert Finberg, of the University of Massachusetts, lead author of the study. "The misperception that it's always better to use a bactericidal drug is incorrect," said Dr. Finberg.

"It's probably important to use bactericidal drugs in treating endocarditis and meningitis," Dr. Finberg added, "but in many situations, cidal drugs are not preferable over static drugs."

###

Founded in 1979, Clinical Infectious Diseases publishes clinical articles twice monthly in a variety of areas of infectious disease, and is one of the most highly regarded journals in this specialty. It is published under the auspices of the Infectious Diseases Society of America (IDSA). Based in Alexandria, Virginia, IDSA is a professional society representing more than 7,700 physicians and scientists who specialize in infectious diseases. For more information, visit http://www.idsociety.org.


Story Source:

The above story is based on materials provided by Infectious Diseases Society Of America. Note: Materials may be edited for content and length.


Cite This Page:

Infectious Diseases Society Of America. "Bacteria-Killing Vs. Bacteria-Inhibiting Drugs In Treating Infections." ScienceDaily. ScienceDaily, 22 October 2004. <www.sciencedaily.com/releases/2004/10/041021083250.htm>.
Infectious Diseases Society Of America. (2004, October 22). Bacteria-Killing Vs. Bacteria-Inhibiting Drugs In Treating Infections. ScienceDaily. Retrieved July 31, 2014 from www.sciencedaily.com/releases/2004/10/041021083250.htm
Infectious Diseases Society Of America. "Bacteria-Killing Vs. Bacteria-Inhibiting Drugs In Treating Infections." ScienceDaily. www.sciencedaily.com/releases/2004/10/041021083250.htm (accessed July 31, 2014).

Share This




More Health & Medicine News

Thursday, July 31, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Dangerous Bacteria Kills One in Florida

Dangerous Bacteria Kills One in Florida

AP (July 31, 2014) Sarasota County, Florida health officials have issued a warning against eating raw oysters and exposing open wounds to coastal and inland waters after a dangerous bacteria killed one person and made another sick. (July 31) Video provided by AP
Powered by NewsLook.com
Health Insurers' Profits Slide

Health Insurers' Profits Slide

Reuters - Business Video Online (July 30, 2014) Obamacare-related costs were said to be behind the profit plunge at Wellpoint and Humana, but Wellpoint sees the new exchanges boosting its earnings for the full year. Fred Katayama reports. Video provided by Reuters
Powered by NewsLook.com
Peace Corps Pulls Workers From W. Africa Over Ebola Fears

Peace Corps Pulls Workers From W. Africa Over Ebola Fears

Newsy (July 30, 2014) The Peace Corps is one of several U.S.-based organizations to pull workers out of West Africa because of the Ebola outbreak. Video provided by Newsy
Powered by NewsLook.com
Weather Kills 2K A Year, But Storms Aren't The Main Offender

Weather Kills 2K A Year, But Storms Aren't The Main Offender

Newsy (July 30, 2014) Health officials say 2,000 deaths occur each year in the U.S. due to weather, but it's excessive heat and cold that claim the most lives. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

    Environment News

    Technology News



      Save/Print:
      Share:

      Free Subscriptions


      Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

      Get Social & Mobile


      Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

      Have Feedback?


      Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
      Mobile: iPhone Android Web
      Follow: Facebook Twitter Google+
      Subscribe: RSS Feeds Email Newsletters
      Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins