Featured Research

from universities, journals, and other organizations

Magnetic Resonance Imaging Helps Detect Breast Cancer But Does Not Eliminate Need For Biopsy

Date:
December 15, 2004
Source:
Johns Hopkins Medical Institutions
Summary:
A multicenter study of 821 patients referred for breast biopsy based on prior examinations that suggested cancer finds that while magnetic resonance imaging (MRI) distinguishes between benign and malignant breast tumors better than mammography, biopsies are still needed to confirm the diagnosis.

A multicenter study of 821 patients referred for breast biopsy based on prior examinations that suggested cancer finds that while magnetic resonance imaging (MRI) distinguishes between benign and malignant breast tumors better than mammography, biopsies are still needed to confirm the diagnosis.

Related Articles


The study, called the International Breast MR Consortium, was carried out in 14 university hospitals in the United States and Europe, including Johns Hopkins, from June 1998 through October 2001. All patients underwent MRI exams prior to breast biopsy.

David Bluemke, M.D., Ph.D., associate professor of radiology at the Johns Hopkins University School of Medicine, led the Hopkins team that examined 200 of the 821 patients enrolled in the study and reviewed data from all study participants. MRI correctly detected cancer in 356 of 404 cancer cases, resulting in a sensitivity of 88.1%. It correctly identified as negative for cancer 281 of 417 cases without cancer, producing a specificity rate of 67.7%, compared to 52.8% for mammography.

While MRI was good at finding cancer, it was less effective in ruling out malignancies, Bluemke says. "People who have an abnormal mammogram need to have biopsies of suspicious lesions," he says. "While MRI aids in determining the extent of the cancer, it is not a substitute for breast biopsy. Importantly, however, the MRI was not adversely affected by factors such as breast density, tumor type or menopausal status, which frequently complicates mammographic interpretations."

Bluemky believes MRI will be most beneficial for patients with difficult to interpret mammograms.

###

The study, funded by the National Cancer Institute, is published in the December 8 issue of the Journal of the American Medical Association.


Story Source:

The above story is based on materials provided by Johns Hopkins Medical Institutions. Note: Materials may be edited for content and length.


Cite This Page:

Johns Hopkins Medical Institutions. "Magnetic Resonance Imaging Helps Detect Breast Cancer But Does Not Eliminate Need For Biopsy." ScienceDaily. ScienceDaily, 15 December 2004. <www.sciencedaily.com/releases/2004/12/041208083612.htm>.
Johns Hopkins Medical Institutions. (2004, December 15). Magnetic Resonance Imaging Helps Detect Breast Cancer But Does Not Eliminate Need For Biopsy. ScienceDaily. Retrieved March 30, 2015 from www.sciencedaily.com/releases/2004/12/041208083612.htm
Johns Hopkins Medical Institutions. "Magnetic Resonance Imaging Helps Detect Breast Cancer But Does Not Eliminate Need For Biopsy." ScienceDaily. www.sciencedaily.com/releases/2004/12/041208083612.htm (accessed March 30, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Monday, March 30, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

S. Leone in New Anti-Ebola Lockdown

S. Leone in New Anti-Ebola Lockdown

AFP (Mar. 28, 2015) Sierra Leone imposed a three-day nationwide lockdown Friday for the second time in six months in a bid to prevent a resurgence of the deadly Ebola virus. Duration: 01:17 Video provided by AFP
Powered by NewsLook.com
These Popular Antibiotics Can Cause Permanent Nerve Damage

These Popular Antibiotics Can Cause Permanent Nerve Damage

Newsy (Mar. 27, 2015) A popular class of antibiotic can leave patients in severe pain and even result in permanent nerve damage. Video provided by Newsy
Powered by NewsLook.com
WH Plan to Fight Antibiotic-Resistant Germs

WH Plan to Fight Antibiotic-Resistant Germs

AP (Mar. 27, 2015) The White House on Friday announced a five-year plan to fight the threat posed by antibiotic-resistant bacteria amid fears that once-treatable germs could become deadly. (March 27) Video provided by AP
Powered by NewsLook.com
House Ready to Pass Medicare Doc Bill

House Ready to Pass Medicare Doc Bill

AP (Mar. 26, 2015) In rare bipartisan harmony, congressional leaders pushed a $214 billion bill permanently blocking physician Medicare cuts toward House passage Thursday, moving lawmakers closer to resolving a problem that has plagued them for years. (March 26) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins