Featured Research

from universities, journals, and other organizations

New Therapeutic Vaccine For HIV/AIDS Eliminates Needles And Excessive Toxicity

Date:
January 17, 2005
Source:
Blackwell Publishing Ltd.
Summary:
DermaVir, a novel treatment for HIV/AIDS, offers a new option which complements and improves present drug therapies. The vaccine, applied topically to the skin, has demonstrated efficacy in boosting immune responses and controlling virus replication in chronically infected monkeys. This treatment possibly offers a new, non-invasive option for HIV-infected patients.

DermaVir, a novel treatment for HIV/AIDS, offers a new option which complements and improves present drug therapies. The vaccine, applied topically to the skin, has demonstrated efficacy in boosting immune responses and controlling virus replication in chronically infected monkeys. This treatment possibly offers a new, non-invasive option for HIV-infected patients.

"The immune system demonstrated an unexpected capacity for recovery after DermaVir vaccinations in these monkeys, some of which had already progressed to AIDS before starting treatment," states lead researcher, Julianna Lisziewicz, Ph.D. Though the immune control is not permanent, data shows that antiviral activity of immune responses induced by DermaVir are significantly longer than that of existing antiviral drugs. It is suggested that DermaVir would only need to be re-administered periodically, about 8 times a year, rather than daily.

Current antiretroviral therapies used to treat HIV combine several medications and are sometimes referred to as "cocktails." Together, these drugs work to prevent the virus from multiplying. DermaVir is different from these treatments in that it induces HIV-specific immune reconstitution rather than targeting the virus, and is applied to the skin, rather than orally or through injection. Combined with antiretroviral drugs, DermaVir has shown to be more effective than when used alone, and does not have overlapping resistance or toxic characteristics that would otherwise compromise its effectiveness. Additionally, DermaVir side effects are minimal (skin irritation); thus patients might be able to avoid the excessive toxicities of anti-HIV cocktails.

According to the Joint United Nations Programme on HIV/AIDS, there are currently about 39.4 million people worldwide who are living with HIV/AIDS. Of that number, 4.9 million were newly infected with HIV just this year. Globally, just under half of all people living with HIV are female. The numbers are steadily increasing for women and girls particularly in Eastern Europe, Asia andLatin America.


Story Source:

The above story is based on materials provided by Blackwell Publishing Ltd.. Note: Materials may be edited for content and length.


Cite This Page:

Blackwell Publishing Ltd.. "New Therapeutic Vaccine For HIV/AIDS Eliminates Needles And Excessive Toxicity." ScienceDaily. ScienceDaily, 17 January 2005. <www.sciencedaily.com/releases/2005/01/050110120359.htm>.
Blackwell Publishing Ltd.. (2005, January 17). New Therapeutic Vaccine For HIV/AIDS Eliminates Needles And Excessive Toxicity. ScienceDaily. Retrieved August 1, 2014 from www.sciencedaily.com/releases/2005/01/050110120359.htm
Blackwell Publishing Ltd.. "New Therapeutic Vaccine For HIV/AIDS Eliminates Needles And Excessive Toxicity." ScienceDaily. www.sciencedaily.com/releases/2005/01/050110120359.htm (accessed August 1, 2014).

Share This




More Health & Medicine News

Friday, August 1, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Texas Quintuplets Head Home

Texas Quintuplets Head Home

Reuters - US Online Video (Aug. 1, 2014) After four months in the hospital, the first quintuplets to be born at Baylor University Medical Center head home. Linda So reports. Video provided by Reuters
Powered by NewsLook.com
Ebola Patient Coming to U.S. for Treatment

Ebola Patient Coming to U.S. for Treatment

Reuters - US Online Video (Aug. 1, 2014) A U.S. aid worker infected with Ebola while working in West Africa will be treated in a high security ward at Emory University in Atlanta. Linda So reports. Video provided by Reuters
Powered by NewsLook.com
Ebola Vaccine Might Be Coming, But Where's It Been?

Ebola Vaccine Might Be Coming, But Where's It Been?

Newsy (Aug. 1, 2014) Health officials are working to fast-track a vaccine — the West-African Ebola outbreak has killed more than 700. But why didn't we already have one? Video provided by Newsy
Powered by NewsLook.com
Study Links Certain Birth Control Pills To Breast Cancer

Study Links Certain Birth Control Pills To Breast Cancer

Newsy (Aug. 1, 2014) Previous studies have made the link between birth control and breast cancer, but the latest makes the link to high-estrogen oral contraceptives. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins