Featured Research

from universities, journals, and other organizations

First Detailed Picture Of Migraine Attack

Date:
August 23, 2005
Source:
Swedish Research Council
Summary:
Every eighth adult Swede suffers from migraine. Using a new method, researchers at Göteborg have managed for the first time ever to provide a detailed picture of an untreated attack. This will be of great significance for the development of new forms of treatment. The findings are reported in a dissertation at the Sahgrenska Academy.

Every eighth adult Swede suffers from migraine. Using a newmethod, researchers at Göteborg have managed for the first time ever toprovide a detailed picture of an untreated attack. This will be ofgreat significance for the development of new forms of treatment. Thefindings are reported in a dissertation at the Sahgrenska Academy.

Inthe first nation-wide study of migraine in Sweden, it is shown that onemillion individuals, more than 13 percent of the adult population,suffer from migraine. In total they experience some ten million attackseach year. The condition is characterized by an intensive pulsingheadache, hypersensitivity to light and sound, and severe nausea andvomiting. Migraine is roughly twice as common among Swedish women asSwedish men. About 200,000 Swedes have migraine without being awarethat their symptoms are classified as such. A majority of thoseaffected report negative impact on the highest ranking factors in life,such as family life and the ability to perform their work and enjoymeaningful leisure time.

Only every fourth individual withmigraine is seeing a doctor, which is a lower figure than for the restof the western world. The study shows moreover that every thirdindividual who has seen a doctor regards the information about varioustreatment options as poor or extremely poor.

"Many people hadgone to their doctor previously but stopped. This is remarkableconsidering the fact that most people want to try another migrainetreatment than their current one," says Mattias Linde, a medicalspecialist in neurology and author of the dissertation.

In hisdissertation Mattias Linde has managed to use a new method to capturedetailed pictures of migraine attacks. A number of patients who couldstand to refrain from any treatment for 72 hours were asked to assessthe intensity of the various migraine symptoms on a hundred-degreescale. In this way he was able for the first time to produce a highlyexact picture of how a migraine attack develops hour by hour.

"Thisis a breakthrough that provides research with a new and unique pictureof the great complexity and wealth of variation that characterizes thisenigmatic condition. The pain tends to follow a slowly undulatingrhythm between medium and insufferable intensity," says Mattias Linde.

Thefindings show that acute drugs often provide good but short-livedrelief, whereupon the complaints return to their original pattern aftera couple of hours. The conclusion is that the various symptoms aredriven by a common factor in the brain, and that modern treatments forattacks fail to block off this unknown area.

The overwhelminglydominant thinking among migraine researchers internationally, and notleast in the U.S., is that a condition for effective treatment is thatit must be ingested early in the course of an attack before the painmounts. This has now been refuted by Mattias Linde, who has comparedearly and late injection treatment in the same patients. Nostatistically significant difference was shown, and a majority of thepatients felt that the treatment was equally effective whenadministered late, during high levels of pain.

"It's reassuringnow to be able to encourage patients to take their treatment, either asa nasal spray or as a suppository, even if they didn't do so at anearly stage," says Mattias Linde.

Many patients experience sideeffects of modern treatments for attacks in the form of unpleasant andsometime painful sensations. For example, it can be painful to comeinto contact with water, which often leads to a concern that patientswill avoid taking their medicine. The dissertation shows that this is abenign and short-lived phenomenon resulting from a lowering of the painthreshold in the nervous system.


Story Source:

The above story is based on materials provided by Swedish Research Council. Note: Materials may be edited for content and length.


Cite This Page:

Swedish Research Council. "First Detailed Picture Of Migraine Attack." ScienceDaily. ScienceDaily, 23 August 2005. <www.sciencedaily.com/releases/2005/08/050821232046.htm>.
Swedish Research Council. (2005, August 23). First Detailed Picture Of Migraine Attack. ScienceDaily. Retrieved July 25, 2014 from www.sciencedaily.com/releases/2005/08/050821232046.htm
Swedish Research Council. "First Detailed Picture Of Migraine Attack." ScienceDaily. www.sciencedaily.com/releases/2005/08/050821232046.htm (accessed July 25, 2014).

Share This




More Mind & Brain News

Friday, July 25, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Beatings and Addiction: Pakistan Drug 'clinic' Tortures Patients

Beatings and Addiction: Pakistan Drug 'clinic' Tortures Patients

AFP (July 24, 2014) — A so-called drugs rehab 'clinic' is closed down in Pakistan after police find scores of ‘patients’ chained up alleging serial abuse. Duration 03:05 Video provided by AFP
Powered by NewsLook.com
New Painkiller Designed To Discourage Abuse: Will It Work?

New Painkiller Designed To Discourage Abuse: Will It Work?

Newsy (July 24, 2014) — The FDA approved Targiniq ER on Wednesday, a painkiller designed to keep users from abusing it. Like any new medication, however, it has doubters. Video provided by Newsy
Powered by NewsLook.com
Can Watching TV Make You Feel Like A Failure?

Can Watching TV Make You Feel Like A Failure?

Newsy (July 24, 2014) — A study by German researchers claims watching TV while you're stressed out can make you feel guilty and like a failure. Video provided by Newsy
Powered by NewsLook.com
China's Ageing Millions Look Forward to Bleak Future

China's Ageing Millions Look Forward to Bleak Future

AFP (July 24, 2014) — China's elderly population is expanding so quickly that children struggle to look after them, pushing them to do something unexpected in Chinese society- move their parents into a nursing home. Duration: 02:07 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

    Health News

      Environment News

        Technology News



          Save/Print:
          Share:  

          Free Subscriptions


          Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

          Get Social & Mobile


          Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

          Have Feedback?


          Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
          Mobile iPhone Android Web
          Follow Facebook Twitter Google+
          Subscribe RSS Feeds Email Newsletters
          Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins