Featured Research

from universities, journals, and other organizations

Speed Of PSA Rise Helps Predict Survival For Prostate Cancer Patients

Date:
October 1, 2005
Source:
American Society for Therapeutic Radiology and Oncology
Summary:
The clinical outcome for prostate cancer patients who have been treated with hormone therapy and radiation therapy can usually be determined by how rapidly their prostate specific antigen level rises following treatment, according to a report published in the October 1, 2005 issue of the International Journal of Radiation Oncology*Biology*Physics, the official journal of ASTRO.

The clinical outcome for prostate cancer patients who have been treatedwith hormone therapy and radiation therapy can usually be determined byhow rapidly their prostate specific antigen level rises followingtreatment, according to a report published in the October 1, 2005 issueof the International Journal of Radiation Oncology*Biology*Physics, theofficial journal of ASTRO.

Doctors at M.D. Anderson Cancer Center in Houston studied 621 menwith prostate cancer treated with hormone and radiation therapy between1989 and 2003 to determine whether clinical failure after theirtreatment correlated with the speed at which their post treatment PSAlevel rose. Clinical failure was defined as cancer recurring in theprostate or spreading to other parts of the body.

Researchers found that measuring how quickly the PSA leveldoubled was a good indicator of subsequent poor clinical outcomes,including cancer developing in other parts of the body or death relatedto prostate cancer.

Patients whose PSA level doubled within eight months aftertreatment failure were more likely to have the cancer return or spreadto other parts of the body than patients whose PSA did not double ineight months or less. The estimated five-year rate of clinical failurefor patients with a PSA doubling time of more than eight months wasonly 9.4 percent while 60.4 percent of patients whose PSA doubling timewas less than or equal to eight months could expect some type ofclinical failure.

"The PSA doubling time is an important indicator of how well apatient will recover from prostate cancer," said Andrew K. Lee, M.D.,lead author of the study and a radiation oncologist at M.D. AndersonCancer Center in Houston. "Although clinical outcomes may be positivelyaffected if the patient receives hormone therapy with radiationtherapy, a quickly rising PSA level unfortunately still portends poorresults for these patients."

###

For more information on radiation therapy for prostate cancer, please visit http://www.rtanswers.org.

ASTRO is the largest radiation oncology society in the world,with more than 8,000 members who specialize in treating patients withradiation therapies. As a leading organization in radiation oncology,biology and physics, the Society is dedicated to the advancement of thepractice of radiation oncology by promoting excellence in patient care,providing opportunities for educational and professional development,promoting research and disseminating research results and representingradiation oncology in a rapidly evolving socioeconomic healthcareenvironment.


Story Source:

The above story is based on materials provided by American Society for Therapeutic Radiology and Oncology. Note: Materials may be edited for content and length.


Cite This Page:

American Society for Therapeutic Radiology and Oncology. "Speed Of PSA Rise Helps Predict Survival For Prostate Cancer Patients." ScienceDaily. ScienceDaily, 1 October 2005. <www.sciencedaily.com/releases/2005/10/051001101436.htm>.
American Society for Therapeutic Radiology and Oncology. (2005, October 1). Speed Of PSA Rise Helps Predict Survival For Prostate Cancer Patients. ScienceDaily. Retrieved September 23, 2014 from www.sciencedaily.com/releases/2005/10/051001101436.htm
American Society for Therapeutic Radiology and Oncology. "Speed Of PSA Rise Helps Predict Survival For Prostate Cancer Patients." ScienceDaily. www.sciencedaily.com/releases/2005/10/051001101436.htm (accessed September 23, 2014).

Share This



More Health & Medicine News

Tuesday, September 23, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Ebola Costs Keep Mounting

Ebola Costs Keep Mounting

Reuters - Business Video Online (Sep. 23, 2014) The WHO has warned up to 20,000 people could be infected with Ebola over the next few weeks. As Sonia Legg reports, the implications for the West African countries suffering from the disease are huge. Video provided by Reuters
Powered by NewsLook.com
Liberia Pleads for Help to Fight Ebola

Liberia Pleads for Help to Fight Ebola

AP (Sep. 22, 2014) Liberia's finance minister is urging the international community to quickly follow through on pledges of cash to battle Ebola. Bodies are piling up in the capital Monrovia as the nation awaits more help. (Sept. 22) Video provided by AP
Powered by NewsLook.com
Ebola Doctor Says Border Controls Critical

Ebola Doctor Says Border Controls Critical

AP (Sep. 22, 2014) A Florida doctor who helped fight the expanding Ebola outbreak in West Africa says the disease can be stopped, but only if nations quickly step up their response and make border control a priority. (Sept. 22) Video provided by AP
Powered by NewsLook.com
Global Ebola Aid Increasing But Critics Say It's Late

Global Ebola Aid Increasing But Critics Say It's Late

Newsy (Sep. 21, 2014) More than 100 tons of medical supplies were sent to West Africa on Saturday, but aid workers say the global response is still sluggish. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins